Objective To explore the clinical treatment effects of high risk lying-in women with postpartum hemorrhage by using B-Lynch suture combined misoprostol.Methods 82 high risk lying-in women with postpar-tum hemorrhage underwent cesarean delivery,were randomly divided into the observation group A ( n=42) and the controlled group B(n=40).B-Lynch suture combined misoprostol were used for preventive treatment in group A, and misoprostol were used in group B.Amount of bleeding,the effects and complications of lying-in women in group A and group B were observed and comparerd.Results There were significant differences in amount of bleeding of intraoperative period (t=-27.758,P<0.01),2 hours (t=-22.717,P<0.01) and 24 hours (t=-48.162,P<0.01) after delivery in group A and group B (P<0.01),respectively.The total effective rate of group A was superior to that of group B(χ2 =6.797,P<0.01).The complication incidence in group A was significantly lower than that in group B (χ2 =28.616,P<0.01).Conclusion The treatment effects of B-Lynch suture combined misoprostol for high risk lying-in women are superior.It can reduce significantly the intraoperative and postoporative amount of bleeding,and decrease complication incidence.The method is easy to master and ought to be promoted in the clinic.

This paper reports the efficacy of allosteric snake neurotoxin in the treatment of 114 cases of motor neuron disease. The drug was given intramuscularly once a day with a dose of 2 ml (500 ?g/ml) in 68 cases of amyotrophic lateral sclerosis, 40 cases of progressive muscular atrophy and 6 cases of primary lateral sclerosis. Eighty-three cases were followed up from 3 to 28 months. The recent therapeutic effects observed were as follows : there was some improvement in 20 cases (24.1%), stability of disease in 26 cases (31.3%) and no effect in 37 cases (44.6%).The clinical effectiveness of modified neurotoxin is evaluated and the possible mechanism of its therapeutic action is also discussed.

Objective To observe the treatment effect of transplanted autogenous bone marrow stroma cells (BMS-C) absorbed in the type-Ⅰ collagen matrix in bone repair. Methods Thirty-two adult white New Zealand rabbits were randomly divided into Group Ⅰ and Group Ⅱ. The bone marrow was extracted from tubercle and greater trochanter of femur for culture. Then, the cells were amplified, implanted into type-Ⅰ collagen matrix and further cultured for two weeks. Two weeks later, the cells were implanted into the 1.5 cm radius defect. In the Group Ⅰ, management A (BMS-C+type-Ⅰ collagen) was given to the defect of one radius and management B (control) to the defect of the contralateral radius. In the Group Ⅱ, the defect of one radius was given management A and the defect of the contralateral radius management C (type-Ⅰ collagen).The rabbits were killed 8 and 12 weeks after implantation, the effect of three managements was compared. Results Twelve weeks after implantation, in the management A, all specimens had complete bony union; and in the management B, the specimens were filled with fibrous tissues; in the management C, a little scar formed. Conclusions BMS-C absorbed in the type-Ⅰ collagen can effectively repair bone defect.

Objective To investigate the clinical effect of laparoscopic operation and laparotomy in the treat-ment of uterine fibroids.Methods A retrospective analysis of uterine fibroids and requests to retain the clinical data of 380 cases of uterine of patients,according to treatment methods,they were divided into laparoscopic myomectomy group (group A)and cesarean section uterine fibroids removed surgery group (B group),there were 190 cases,two groups of patients,surgery,clinical effect were analyzed.Results In group A,operation time,postoperative exhaust time,postoperative ambulation time,postoperative VAS score,duration of hospitalization,injection of analgesics appli-cation proportion were (96 ±35)min,(24 ±8.5)h,(12 ±4)h,(2.0 ±1.5),(4.0 ±1.2)d,17.8%,patients in the group B respectively (98 ±28)min,(40 ±12)h,(20 ±8)h,(6.0 ±1.3),(8 ±2)d,84.6% there was a significant differences between the two groups (t=-2.558,33.96,45.810,50.571,34.120,χ2 =169.89,all P<0.05);group A and group B,the amount of bleeding were (186 ±78)mL and (175 ±85)mL,with no significant difference between the two groups (t=1.911,P>0.05);group A,the complication rate was 7.34%,lower than the 12.6%in the group B,there was significant difference between the two groups (χ2 =3.923,P<0.05).Conclusion Laparoscopic myo-mectomy in treatment of uterine fibroids,good effect,less trauma,quicker recovery,shorter hospitalization time of patients,should be further popularized in clinic.

Objective To explore the clinic value of blood loss during and after cesarean section in women with scarred uterus. Methods From July 2007 to December 2008, thirty-six women with scarred uterus received weighing methods to evaluate the actual blood loss during and after cesarean section in Yuhuangding hospital, while 98 cases without pregnant complications were chosen as control. Results In women with scarred uterus, the blood loss during operation Was (372.4 ± 180.0) ml, and the total amount after 2 hours and 24 hours were (444.7± 228.2) ml and (527.4 ±251.6) ml respectively, which were higher than corresponding values in control group (P < 0. 05). The incidence of postpartum hemorrhage in scarred uterus was 47.2%, higher than that in control group (P < 0. 05). There were no significant differences between two groups in the tests of hemoglobin and coagulation functions (P > 0. 05). Conclusions Scarred uterus may be one of the important reasons which lead to postpartum hemorrhage. The clinical treatment of pregnant women with scarred uterus should focus on the prevention of blood loss during the cesarean section.

Objective To analysis effect of midazolam combined with etomidate on liver function, malondialdehyde(MDA) , superoxide dismutase (SOD) levels after laparoscopic cholecystectomy.Methods 80 patients who were undergoing laparoscopic cholecystectomy were collected,all patients were randomly divided into control group and experimental group, 40 cases in each group,who were given the appropriate anesthesia induction drugs before surgery.After operation,the serum levels of MDA, SOD, glutathione peroxidase(GSH-Px) and the liver function were detected in all patients. Results After operation, compared with control group, the serum alanine aminotransferase(ALT) , aspartate aminotransferase (AST) and total bilirubin (TBIL)levels were lower in the experimental group (P<0.05);the serum MDA level was lower in the experimental group (P<0.05);the serum SOD and GSH-PX levels were higher in the experimental group (P<0.05) .Conclusion Midazolam combined with etomidate can reduce oxidative stress reaction in patients after laparoscopic cholecystectomy, which is conducive to the recovery of liver function.

Surgical site infection (SSI)following spinal surgery is the most common complications, which is devastating for both the patient and the surgeon.There is strong evidence in the literature that opti-mizing specific preoperative,intraoperative,and postoperative variables can significantly lower the risk of developing an SSI.Evidence-based approach will allow surgeons to minimize the risk of SSI and,therefore, significantly improve patient care.Here,we review the current evidence.

Objective To evaluate the effectiveness of "screen and target population intervention policy" for stroke intervention in Nanhui county of Shanghai city.Methods A cross sectional survey on stroke was carried out in January 1999,and 696558 population in Nanhui county of Shanghai city were investigated in the study. Surveillance data on incidence and mortality rate of stoke from January 1996 to December 1998 in the county were retrospectively checked and reinvestigated.The CVHI of 35 years old and over in this population which have one and more of risk factors were measured,their CVHI total score

A large-scale population survey has been made to clarify the degree of harm and feature of distribution of cerebrovascular disease (CVD) in China. The sample investigated was 5814851 from about a billion people in 29 provinces, municipal cities and autonomous regions except Taiwan in China. The incidence, prevalence and mortality rates have been standardized by the direct method using the world standard population. It has been found that the incidence rate of CVD in China was 109.95 per 100 000 people in 1986 and its 95%CI (confidence interval) was 107. 25 ~ 112. 65 per 100000. The age-standardized incidence rate was 115.87/100000. The point prevalence rate of CVD in China was 245.49 per 100000 people on December 31, 1986 and its 95%CI was 241.57-249.61 per 100000, with an age-standardized prevalence rate of 259.86 per 100000. The mortality rate of CVD was 76.78 per 100000 in 1986 and its 95%CI 74.52~79.04 per 100000, with an age-standardized mortality rate of 80.94 per 100000. It has also been found that there was a tendency for the rates to increase gradually from south to north and to decrease progressively from east to west. The models of linear regression have been established between latitude and rates as well as between longitude and rates, respectively. The incidence, prevalence and mortality rates of CVD differ significantly in various topographic areas. They were much higher in cities than in rural areas, and much higher in men than in women. The incidence, prevalence and mortality rates increased with the age, and their relationships were fitted with logistic curve, respectively.

Point prevalence rate of complete stroke on December 31, 1986 in China was investigated using a retrospecive section study for 5 814 851 people of 29 provinces and cities (excluding Taiwan province), and 14275 stroke cases were found. Point prevalence rate was 245.49 per 100000 people with 95% CI (confidence interval) 241.57-249.61 per 100000 people. The rate standardized by the constituent ratio of population between city and rural area of China in 1986 was 247.66 per 100000 people. The rate age-standardized by the population of China in 1982 accounted for 191.92 per 100000 and the rate agestandardized by the world standard population was 259.86 per 100000 people.It has also been found that there was a tendency for the prevalence rates to increase gradually from south to north and to decrease progressively from east to west. The linear regression models have been fitted between the point prevalence rates and latitude or longitude respectively. The results were Y= 12.3819?-1107.38 (tb = 4.65 df = 5 P = 0.0056) for longitudes and Y = 12.6279?-146.6266 (tb = 11.7517 df = 4 P = 0.0003) for latitudes. There was a difference statistically among various topographic areas. The prevalence rate was much higher in urban areas than rural areas and much higher in men than in women. The prevalence rate increased with age and their relationships have been fitted well with the logistic curve.