1.Studies on the Preparation of Machixian Oral Liquid
Jing ZHOU ; Guijie TIAN ; Jingweil FU
Chinese Traditional and Herbal Drugs 1994;0(05):-
Machixian Oral liquid was made from Portulaca oleracea L. Pharmacologic studies proved that it can obviously inhibit blood platelet aggregation and showed hypolipemia activity.A comprehensive investigation of the preparation was studied and a practical quality control was dcvised to ensure its therapeutic efrect.
3.Effects of 9- cis- retinoic acid on transcription of cyclin D1, cdk4 in lung adenocarcinoma cells
Guijie REN ; Zhifang LIU ; Lei DING ; Guoqiang HU ; Xiaoyan HU ; Keli TIAN ; Xueyan YU
Chinese Journal of Pathophysiology 1986;0(03):-
AIM:To investigate the mechanism of 9-cis-RA inhibiting the growth of lung adenocarcinoma cells, and we detect the expressional changes of cyclinD1 and cdk4 in lung adenocarcinoma cells PG, A_(549), SPC-A_1 before and after being treated with 9-cis-retinoic acid(9-cis-RA). METHODS: RT-PCR was used to analyse the transcriptional changes of cyclinD1 and cdk4 in PG, A_(549) and SPC-A_1. RESULTS:9-cis-RA decreased the transcription of cyclinD1 in PG and A_(549)(P