We have enhanced the quality and efficiency of nursing through the management of the work by means of standard quantized integration. The measures include formulation in the first place of various quantized standards and detailed assessment rules and then the working out of assessment methods. The adoption of these measures in our hospital has led to the improvement of its managerial expertise, the enhancement of its nursing personnels quality and competition awareness, the stimulation of its staffs enthusiasm, and the strengthening of its nursing work in teaching and research management. As a result, nursing in the hospital has become more scientific and efficient.

Objective:To evaluate the clinicopathologic characteristics and outcomes of HIV-negative plasmablastic lymphoma (PBL) .Methods:Medical records of 15 patients diagnosed with HIV-negative PBL in Changhai Hospital between January 2013 and August 2019 were reviewed, and clinicopathologic characteristics and outcomes were analyzed.Results:Median age was 59 years (range: 17-69) . All patients had extranodal involvement. According to the Cotswolds-modified Ann Arbor staging system, 1 (6.7%) , 2 (13.3%) , 3 (20.0%) , and 9 (60.0%) patients were classified as at Ⅰ,Ⅱ,Ⅲ and Ⅳ, respectively. Plasmablast and immunoblast proliferations were typical manifestations of PBL. Immunohistochemical staining showed tumor cells were diffusely positive for plasma cell markers CD38, CD138, and Mum-1, while negative for B cell markers CD20, CD10, PAX-5, and BCL-6. Median Ki-67 index was 80% (70%-90%) . Epstein-Barr virus-encoded RNA (EBER) expression was detected in 3 patients, and 1 of them was positive. All patients received chemotherapy, 80% combined with bortezomib as the first line, and responses were observed in 8 patients (6 complete and 2 partial responses) . Median progression-free survival (PFS) and overall survival (OS) were 6.8 (95% CI 2.5-11.1) months and 17.9 (95% CI 5.6-30.2) months, the 3-year PFS and OS rates were 21.2% (95% CI 1.4%-56.8%) and 38.5% (95% CI 12.0%-65.0%) , respectively. Conclusion:HIV-negative PBL with high invasiveness is extremely prone to extranodal involvement and most patients were at the advanced stage. Patients receiving an intensive therapy combined with bortezomib and bridged autologous stem cell transplantation may improve long-time survival.

Objective To investigate the sexual function and its impact factors in recipients after liver transplantation (LT). Methods Clinical data of 69 recipients undergoing LT in Liver Transplantation Center, the Third Affiliated Hospital of Sun Yat-sen University from June 2007 to July 2012 were analyzed retrospectively. The informed consents of all recipients were obtained and the ethical committee approval was received. All the recipients were male with age ranging from 30 to 55 years old and a median of 43 years old. The sexual function was normal in all patients before being diseased. The recipients were surveyed using self-designed questionnaire on sexual life quality of liver transplant recipients and direct inquiry. The recipients were divided into sexual dysfunction group (n=23) and intact sexual function group (n=46). The correlation between sexual dysfunction and clinical indexes of the recipients was analyzed. The ratio of two groups was compared by Chi-square test. Results The incidence of sexual dysfunction of liver transplant recipients after operation was 33% (23/69), which was significantly lower than that before operation [88% (61/69) ] (χ2=7.56, P<0.05). The incidence of sexual dysfunction after operation in recipients with chronic severe hepatitis and decompensated liver cirrhosis [49% (17/35)] was significantly higher than those with compensated liver cirrhosis and liver inflammatory granuloma [18% (6/34)] (χ2=4.52, P<0.05). The incidence of sexual dysfunction was significantly higher in recipients who considered that sexual life causing adverse impacts on the liver graft [83% (20/24)], compared with those who considered that sexual life causing no impacts on the liver graft [7% (3/45) (χ2=11.63, P<0.05)]. Conclusions The sexual function of the recipients after LT improved significantly, compared with that before LT. The incidence of sexual function is closely related with the primary diseases and the cognition on sexual life of the recipients.