Objective To observe the effect of rehabilitation in family on children with cerebral palsy(CP).Methods 20 CP children were observed for 2 years and trained at out-patient department,then continually trained at family by parents who received doctor's instructions one hour every month.Results After comprehensive rehabilitation,4 cases of 20 cases were recovery,6 cases increased extremely,6 cases were effective,4 cases were no obvious changes.Conclusion Rehabilitation in family could reduce the load of family treatment expenses,and is convenient and effective for CP children.

Objective To observe the effects of intrathymic islet transplantation or renal subcapsule islet transplantation on the graft survival.Methods C57BL/6 mice were used as recipients and BALB/c as donors The recipients receiving intrathymic or renal subcapsule islet transplantation were divided into simple transplantation groups and the group intraperitoneally receiving rabbit antithymocyte serum(ATS) at the time of islet transplantation.Results The median survival time (MST) of simple intrathymic allografts were 19.5 days,longer than that of allografts implanted beneath the renal capsule.Administration of ATS at the time of islet transplantation delayed rejection of islets transplanted to the renal subcapsute(MST,43.0 days),and intrathymic allografts were superior(MST,93.8 days).Six of 8 intrathymic grafts with administration of ATS survived permanently.especially a state of donor-specific unresponsiveness was induced.Conclusion The thymus may be an immunoprivileged site for islet transplantation and may play an important role during the induction of immune tolerance.

Magnetic nanoparticle will become a kind of mean and colloidal solution if it is coated with surfacant.Magnetic nanoparticle has a wide clinical practice because it can produce heat in alternating magnetic fields,especially in malignant tumors thearapy.Magnetic nanoparticle hyperthermia,nano-delivery and magnetic target drug,and intravascular embolization with magnetic particle will bring new hope for tumor patients.

Objective To probe into urban residents' mental health knowledge awareness in Jingmen city. Methods By means of self-compiled questionnaires, 563 community residents were surveyed about their mental health knowledge and access to it. Results For mental health- care knowledge, community residents scored a total of (42.52±8.79), among which, (15.34±3.25) points for relevant causes,(12.23±4.89) points for corresponding symptoms, and (14.92±4.26) for health behavior. Such aspects would affect a resident's awareness of mental health knowledge as the resident's education background,marriage and chronic diseases. Radio and television (48.3%), newspapers and magazines (41.4%), hospital expert advice (39.8%), and community medical services (36.1% ) were considered the better access to mental health knowledge. Conclusions Residents had considerably inadequate knowledge of mental health. Therefore, a variety of health- care education activities should be carried out to improve residents'mental health knowledge.

Objective To investigate the effects of two weaning modes of mandatory rate ventilation (MRV) and SIMV+PSV on respiratory mechanics in patients with type Ⅱ respiratory failure. Methods A total of 30 patients with type Ⅱ respiratory failure were sem randomly divided into two groups. Patients with type Ⅱ respiratory failure received ventilation in CMV mode or CMV/ACMV modes and then SIMV+PSV. When patients could be weaned, MRV mode was adopted in MRV group, but SIMV+PSV modes were adopted in the control group. After continuous operation in each mode for 60 min and when the tidal volume (VT) and minute ventilation (MV) in MRV mode were the same as those in SIMV+PSV mode, PIP, PP, Pm, PEEPi, blood gas changes, and weaning success in the two groups were observed during ventilation. Results PIP, PP, and Pm in patients in MRV mode were significantly lower than those in SIMV+PSV modes ( P 0.05), but the synchronism in patients in MRV group was better. Conclusion MRV is a more adaptable weaning mode for patients with type Ⅱ respiratory failure.

ObjectiveTo assess the efficacy and the immunological memory of plasma-derived hepatitis B vac- cine 11 years after the initial inoculation. Methods A randomized, double-blind and placebo-controlled trial design was used. Results The immunogenicity and protection rate of the vaccine were good 1 1 years after vaccination, how- ever, from 9 to 11 years after vaccination, the perscn year HBV infection rate showed no noticeable difference be- tween the vaccine group and placebo-controls. Furthermore, the immunological memory remained 11 years after in- oculation, but was significantly lower than that observed in the past 10 years. Conclusion Vaccine protection wanes over the years. More information is needed to define the appropriate time for vaccine booster doses.

14 d).Compared with 1 h CI,TNF-? expressions in whole liver grafts with 8 h and 16 h CI were markedly increased at 90 min after reperfusion(P

Objective To study the effect of valsartan eluting-stent on vascular neointimal formation and angiotensin Ⅱ type 2 receptor (AT2R) expression and to access its feasibility to prevent in-stent restenosis and the mechanism. Methods Both the valsartan eluting-stents and the carrier eluting-stents were made with multi-layers coated methods. Bare stents, carrier eluting-stents and valsartan eluting-stents were implanted into the rabbits' abdominal aortias respectively. Abdominal aorta angiography was performed before and right after the operation and at 3 months after stent inplantation. The mean diameter of aortas in different groups were measured by Quantitative coronary angiography software. All the rabbits were killed 3 months after the procedure and the cross section of the stented vessel were analysed for neointimal formation. The luminal area, neointimal area, inner elastic membrane luminal area and the maximal inner-membrane thickness were compared between the 3 groups. The expressions of AT2R mRNA and the protein were determined by RT-PCR and histomorphometry. Results There were no significant differences in the mean aortic diameters among the 3 groups.The greatest luminal area and the minimal neointimal hyperplasia was found in the valsartan eluting-stents group compared with the other two groups. The mean luminal areas of the bare stents, carrier eluting stents and the valsartan eluting-stents were 4 345 548?1 258 22 ?m2, 4 302 061?167 952 ?m2 and 5 016 269?207 934 ?m2; the mean neointimal areas were 1 119 635?163 503 ?m2, 1 135 636?136 555 ?m2 and 441 577?74 099 ?m2 and the mean maximal inner-membrane thickness were 210?30 ?m, 192?21 ?m and 116?12 ?m respectively.The level of AT2R mRNA expression in the valsartan eluting-stents group was higher than that in the other two groups. The transcription of AT2R protein showed similar trend. Conclusion Valsartan eluting-stents enhanced AT2R mRNA and protein expression and inhibited neointimal hyperplasia which might play an important role in preventing restenosis.

Objective To explore the role of granulocyte macrophage colonystimulating factor(GM-CSF),C reaction protein(CRP)and tumor necrosis factor-?lpha(TNF?)in infant cytomegalovirus hepatitis.Methods Cytomegalovirus DNA of 56 cases of children with cytomegalovirus hepatitis and 51 normal controls in blood were detected using FQ-PCR.The levels of GM-CSF and TNF?in serum were assayed with ELISA,and CRP was measured with immunoturbidmemetry assay.Results The levels of M-CSF,CRP and TNF? in serum of infant cytomegalovirus hepatitis were higher obviously than those in serum of the normal control group.Conclution M-CSF,CRP and TNF? participate in pathological immune response and anti-infective immunity of cytomegalovirus hepatitis.

Objective To analyze the clinical characteristics of children infecting with Epstein -Barr virus. And in purpose to improve the knowledge of children infecting with Epstein -Barr virus.Methods We analyzed retrospectively to 97 cases of children which serodiagnosis of Epstein -Barr virus infectius in the aspects of the onset season,the age,clinical characteristics.And compared with complication group and no complication group in the aspects of the white cell count,neutrophils to white cell count ratio,lymphocyte to white cell count ratio and C -reactive protein.And contrasted the presence of statistical difference.Results The peak months were spring and summer(58 cases);Pre -school age was the peak age of EBV infectious(41 cases),and the rest respectively were toddlers age(33 cases),school age and youth(20 cases)and infant period(3 cases).The most frequently clinical manifestation respectively was pharyngitis,and other such as fever,lymphadenopathy,hepatosplenomegaly.There had no statistical difference in the two groups of complication group and no complication group in the aspects of the white cell count,neutrophils to white cell count ratio,lymphocyte to white cell count ratio and C -reactive protein(P >0.05).Conclusion The infant can suffer from infectious mononucleosis infect with EBV.Infectious mononucleosis have a variety of clinical manifestation,which always have some complications.The diognosis should combinate clini-cal manifestation with laberatory test.