Objective To explore the effect of deep vein thrombosis(DVT)assessment scale on prevention of deep vein thrombosis in malignant tumor patients?Methods Eight hundred malignant tumor patients were divided into intervention group and control group according to admission time,400 cases in each group?The control group received traditional nursing.Methods of treatment and nursing,while the intervention group received pertinent nursing care based on the risk factors for DVT induced for the investigation among the patients using deep vein thrombus assessment scale.Result The incidence of DVT in the intervention group was significantly lower than that of the control group(P<0?05).Conclusions The deep vein thrombosis assessment scale may effectively predict the population at high risk of deep vein thrombosis?The implementation of effective nursing intervention may reduce the incidence of DVT?

Objective To investigate the clinical efficacy of Hiru doid,Sufu and Musk Hemorrhoids Ointment on preventing peripheral chemothera?peutic phlebitis due to continuous infusion of 5?fluorouracil. Methods Totally 90 patients with esophageal squamous cell carcinoma treated with continuous infusion of 5?fluorouracil were recruited and randomly divided into Hirudoid group,Sufu group and Musk Hemorrhoids Ointment group, with 30 cases in each group. Three groups were applied with drugs respectively along the vein punctured while connecting the pump of 5?fluorouracil 3 times a day(each time interval of 6 hours)for 5 consecutive days. The occurrence of chemotherapy phlebitis was observed and recorded. Results Musk Hemorrhoids Ointment and Sufu were more effective than Hirudoid in reducing the incidence of phlebitis and relieving the degree of venous in?jury(P<0.05);however,there were no differences between Musk Hemorrhoids Ointment and Sufu(P>0.05). Musk Hemorrhoids Ointment was the most effective among the three in relieving the pain caused by phlebitis(P<0.05). There were no difference between Sufu and Hirudoid(P>0.05). Conclusion Musk Hemorrhoids Ointment can effectively prevent peripheral chemotherapeutic phlebitis caused by continuous infusion of 5?fluorouracil with affordable expense which is worthy of promotion in clinic use.

Objective To investigate application effect of fatigue factor intervention in breast cancer patients during operation.Methods A total of 60 breast cancer patients were ran-domly divided into observation group and control group.The control group received routine nursing while the observation group was given fatigue factor intervention based on the control group.Sur-gical efficacy,postoperative self-efficacy and life quality of two groups were compared.Results Fatigue degree score in the observation group was lower than that in the control group,postopera-tive complication and hospitalization time less than that in the control group,self-efficacy was higher than that in the control group,there were statistically significant differences(P <0.05). Life quality in the observation group was higher than that in the control group,there was statisti-cally significant difference(P <0.05).Conclusion Fatigue factor intervention is conducive to the postoperative recovery of breast cancer patients and it ensures the operation effect and improves the life quality.

Objective To investigate application effect of fatigue factor intervention in breast cancer patients during operation.Methods A total of 60 breast cancer patients were ran-domly divided into observation group and control group.The control group received routine nursing while the observation group was given fatigue factor intervention based on the control group.Sur-gical efficacy,postoperative self-efficacy and life quality of two groups were compared.Results Fatigue degree score in the observation group was lower than that in the control group,postopera-tive complication and hospitalization time less than that in the control group,self-efficacy was higher than that in the control group,there were statistically significant differences(P <0.05). Life quality in the observation group was higher than that in the control group,there was statisti-cally significant difference(P <0.05).Conclusion Fatigue factor intervention is conducive to the postoperative recovery of breast cancer patients and it ensures the operation effect and improves the life quality.

Objective To explore effects of diet detail nursing on swallowing function and quality of life in patients with mild-to-moderate dysphasia after oral cancer surgery. Methods Totally 66 patients with dysphasia after oral cancer surgery in Department of Head and Neck Surgery of Liaoning Cancer Hospital were selected by convenience sampling and divided into control group and observation group by random number table method,with 33 cases in each group. The two groups were given dysphasia training,and the control group was given regular diet nursing,on which basis the observation group was given diet detail nursing. The dysphasia degree was assessed by water swallow test. The pharyngeal contraction rate was evaluated by swallowing radiography,and the correctness of swallowing methods was evaluated. The quality of life of patients was assessed by University of Washington Quality of Life Scale (UWQOL),and the nutritional status and postoperative complications were observed. Results After intervention,the dysphasia degree in observation group was lighter than that in control group (P＜ 0.05). The pharyngeal contraction rates of swallowing dilute fluid and thick fluid in observation group[(34.47±7.56)% and (36.48±9.46)%] were smaller than those in control group [(38.94±9.27)% and (41.46±10.42)%] (P＜ 0.05). The correct rate of swallowing methods in observation group(84.85%) was significantly higher than that in control group (63.64%) (P＜0.05). The scores of five items of swallowing,chewing,mood,anxiety and self-assessment quality of life in observation group were higher than those in the control group (P＜0.05). The serum albumin level in observation group(38.66±4.85g/L) was higher than that in control group (35.84±5.16 g/L) (P＜ 0.05). The incidence rate of aspiration in observation group(12.12%) was smaller than that in control group (33.33%)(P＜ 0.05). Conclusions Diet detail nursing management for patients with dysphasia after oral cancer surgery can guide patients to master the correct swallowing methods,effectively reduce the pharyngeal contraction rate,improve the swallowing ability, reduce the occurrence of aspiration,and improve their quality of life and nutritional status to a certain extent.

Objective:To explore the application effect of time-sensitive incentive theory in malnourished patients with advanced ovarian cancer.Methods:Using the convenient sampling method, a total of 80 malnourished patients with advanced ovarian cancer who were admitted to Liaoning Cancer Hospital and Institute from January 2018 and December 2019 were selected as research objects. According to the random number table, they were divided into the observation group (42 cases) and the control group (38 cases) . Patients in the control group received routine nursing, while the observation group used nursing intervention under time-sensitive incentive theory. Self-Perceived Burden Scale (SPBS) , Chinese version of Strategies Used by People to Promote Health (C-SUPPH) , Self-rating Anxiety Scale (SAS) , Self-rating Depression Scale (SDS) and Social Support Rating Scale (SSRS) were used to compare intervention effects.Results:After intervention, scores of SPBS, SAS and SDS of the observation group were lower than those of the control group, and scores of C-SUPPH and SSRS were higher than those of the control group, and the differences were statistically significant ( P<0.05) . After intervention, the nutritional indexes of the observation group were better than those of the control group, and the differences were statistically significant ( P<0.05) . Conclusions:Nursing intervention under the guidance of time-sensitive incentive theory can effectively reduce self-perception burden of malnourished patients with advanced ovarian cancer, improve anxiety, depression and other unhealthy emotions and improve the nutritional level, self-efficacy and social support of patients.

This paper expounds the definition, measurement tools, influencing factors and intervention measures of body image in cancer patients, aiming to provide basis for further clinical research and exploration of effective intervention measures.

OBJECTIVEThe synergic and decreasing toxic effects of mineral water and Chinese herbal compound preparation (MWCHCP) on cisplatin were investigated in sarcoma 180 (S180) mice.

METHODThe S180 mice were treated for 5 days with intraperitoneal injection of cisplatin(7.33 mg x kg(-1)) and oral administration of MWCHCP(1 925, 3 850, 7 700 mg x kg(-1)). Then the mice were killed and the tumor growth inhibition rate, organ index, diarrhea index were determined. Observe pathological sections of stomach to study the protective effect of MWCHCP. Reverse transcription-polymerase chain reaction (RT-PCR) was applied to investigate the tumour necrosis factor-alpha (TNF-alpha) expression level of the intestine.

RESULTCombining with cisplatin and MWCHCP caused a tendency of increasing the tumor growth inhibition rate and significant attenution of cisplatin-induced diarrhea, visceral organ injury, gastric mucosal injury and decreased TNF-alpha mRNA level of intestine.

CONCLUSIONThe present findings suggest that MWCHCP increases the inhibition rate of tumor growth of cisplatin and has a beneficial influence on gastrointestinal lesion induced by cisplatin.

Animals ; Antineoplastic Agents ; administration & dosage ; adverse effects ; Cisplatin ; administration & dosage ; adverse effects ; Disease Models, Animal ; Drug Synergism ; Drug Therapy, Combination ; Drug-Related Side Effects and Adverse Reactions ; Drugs, Chinese Herbal ; administration & dosage ; Humans ; Male ; Mice ; Mineral Waters ; administration & dosage ; Sarcoma 180 ; drug therapy ; pathology

Objective To formulate a rational adjuvant therapeutic evidence-based nursing plan for a ovarian cancer chemotherapy patient with puncture piont infection of peripherally inserted central catheter(PICC).And practice in the clinic to solve the nursing problems in clinical nursing work. Methods According to the condition of the patient and using the PICO principle, we put forward clinical problems. We comprehensively searched the National Guideline Clearinghouse (NGC),Cochrane Library,Pub Med, EMbase,Medline,CNKI,VIP and Wanfang Data from 2007 to 2017. Relevant clinical guidelines, evidence summaries, systematic reviews/ Meta-analysis, randomized controlled trials (RCTs), and high quality reviews on nursing puncture piont infection of Peripherally Inserted Central catheter were collected and their authenticity, importance and applicability were evaluated. Results One Meta-analysis, fifteen RCTs, and one review were totally included. According to current evidence as well as the patient′s clinical conditions and preference, a comprehensive and effective adjuvant therapeutic and nursing programme was given to the patient. At the puncture point of PICC infection , PVP iodine was used to hydropathic compress for 15 minutes once a day.After naturally dried, cover with hydrocolloid dressing. After four-day treatment and nursing care, the patient with puncture piont infection had already recovered. Conclusion Evidence-based medicine approaches could help us develop comprehensive therapeutic plans for ovarian cancer chemotherapy patients with puncture piont infection of PICC, promote effectively the puncture point infection recovery,and ensure the normal safe use of PICC .Thereby alleviate pain, improve health, and increase patients′quality of life.

Objective:This study aims to investigate the inner experiences of cancer patients when confronting financial toxicity through a Meta-analytical approach. The goal is to provide evidence-based insights and theoretical references for clinical healthcare professionals to fully understand the feelings and experiences associated with financial toxicity in cancer patients, thereby laying a foundation for targeted interventional measures.Methods:A computerized search was conducted across databases including CINAHL, PubMed, PsycINFO, Embase, Scopus, Web of Science, CNKI, WanFang, VIP, Sinomed and other databases, collecting qualitative studies related to the inner experience of financial toxicity among cancer patients, up until April 12, 2023. Quality appraisal of the included literature was carried out according to JBI′s standards for qualitative research, and results were synthesized using Meta-aggregation methods.Results:Twenty-three studies were included, from which 82 specific outcomes were extracted. These were categorized into 11 new thematic groups and ultimately synthesized into four integrated findings: the impact of objective costs, subjective burden, and unreasonable expectations; diverse cognitive attitudes and management coping strategies; multiple pressures and challenges on patients and their families; and the articulation of needs and perceptions of beneficial growth.Conclusions:Healthcare professionals should pay attention to the financial toxicity issues that patients face at the initial stage of cancer diagnosis. Timely communication about economic issues between patients and healthcare providers is essential to help patients have a preliminary understanding of the impending financial toxicity at the onset of the disease. A comprehensive intervention that emphasizes different aspects of objective and subjective financial toxicity, coupled with multi-dimensional mitigation strategies, can promote active coping in patients, enhance familial emotional and financial support to overcome challenges together, and prioritize patients′ needs and expectations to guide them towards reinforcing positive experiences and minimizing the impact of financial toxicity.