Objective To approach therapeutic effect of captopril combined with amiodarone in treating acute myocardial infarction complicating atrial fibrillatio. Methods Select acute myocardial infarction complicating atrial fibrillatio 62 patients, divide into two groups, therapy bundle offer captopril combine amiodarone, control bundle offer propafenone, compare rate of atrial fibrillatio turn over with 24 houres, control rate of atrial fibrillatio attack (reduce atrial fibrillatio attacking over 60%), tetain sinus rhythn, backward heart failure incidence rate, repeated infarct rate, hospitalization death rate, death rate one year later, stroke incidence rate within one year. Results Captopril combined with amiodarone in treating acute myocardial infarction complicating atrial fibrillatio, it can turn over atrial fibrillatio utility, control atrial fibrillatio attack (reduce atrial fibrillatio attacking over 60%), reduce repeated infarct rate (6.3% vs 16.7%), death rate (9.4% vs 16.7%), backward heart failure incidence rate (9.4% vs 30.0%), stroke incidence rate (3.1% vs 13.3%)(all P<0.01). Conclusions The therapeutic effect is certain about captopril combine amiodarone in treating acute myocardial infarction complicating atrial fibrillatio. And this method is safety. The patient profit from it in many ways. It deserves generalization and application.

With the rapid development of antibody genetic engineering, bispecific antibody technology has been advanced. They are capable of binding two or more different epitopes simultaneously, thus offering specific advantages over natural monoclonal antibodies in immunotherapy. Bispecific antibodies have been successfully used in cancer therapy (e.g. melanoma, Hodgkin's lymphoma, liver cancer, and stomach cancer) and inflammation therapy (e.g. rheumatoid arthritis, psoriasis and Crohn's disease), but are still in their early stage for viral immunotherapy. In this study, we reviewed the research progress of bispecific antibodies for immunotherapy of virus infections, especially those with good effects in vivo and in vitro, to provide references for the research and development of bispecific antibodies for antivirus treatment.
Antibodies, Bispecific ; therapeutic use ; Antibodies, Monoclonal ; Epitopes ; Humans ; Immunotherapy ; Virus Diseases