Objective To compare the efficiency of seretide plus montelukast and seretide only on patients with severe persistent asthma. Methods Fifty patients with severe persistent asthma were randomly divided into two groups treated with seretide plus montelukast or seretide only for 12 weeks. The pulmonary function and clinical symptom before and after treatment were observed in two groups. Results The forced expiratory volume in 1 second (FEV1) after treatment improved significantly in the both groups (P

Objective To investigate the bacteria distribution and drug resistance of lower respairory tract infection of re‐spairtory wards .Methods Sputum from patients with low respiratory tract infection was collected ,K‐B methods and minimun in‐hibitory concentration were used to make distribution and antibiotic resisitance .Results Five hundred and twenty‐nine strains were isolated ,of which gram negative organisms accounted for 416(78 .8% ) ,and gram positive organisms accounted for 88(16 .6% ) ,and fungi accounted for 25(4 .7% ) .In whtich ,the pseudomoas aeruginosa(25 .0% )and acinetobacter baumannii(13 .0% )accounted for the first and second one .Pseudomoas aeruginosa showed varying degrees of resistance to most commomly used antibacterials ,but there were still some alternatives .Acinetobacter baumannii had higher resistance to most commomly used antibacterial ,except for cefoperazone sulbactam .Cefoperazone sulbactam showed high susceptibility to most gram negative organisms and gram positive or‐ganisms .Conclusion In the respiratory wards ,gram negative organisms were predominant in low respiratory tract infection .Pseud‐omoas aeruginosa and acinetobacter baumannii play a main role .The later is resistant to most commonly used antibacterials and the former showes high resisitance except for a few antibacterials .

Objective To understand the demographic characteristics of HIV infected injecting drug users (IDUs) with access to antiretroviral therapy (ART) and to identify the factors influencing their access to methadone maintenance treatment (MMT).Methods Outpatients infected with HIV through injecting drug use were selected from the ART clinics in 2 counties in Yunnan province.They were divided into 2 groups,MMT group and non MMT group.Descriptive epidemiologic analysis was conducted on their demographic characteristics,disease history and high risk behaviors and logistic regression analysis was done to identify the factors associated with the access to MMT.Results Among 635 IDUs (536 males,99 females) surveyed,247 received MMT (38.9％),388 received no MMT(61.1％).The median age was 40.33 years and the median diagnosed HIV infection time was 6.08 years.Multivariate logistic regression indicated that being female (OR=2.40,95％CI:1.00-5.74),educational level of junior high school (OR =3.28,95％CI:1.75-6.14),educational level of senior high school or above (OR =7.10,95 ％CI:1.90-26.62),more than 6 years of diagnosed HIV infection history (OR=3.84,95％CI:2.11-6.98) and HCV positive (OR=6.21,95％CI:3.06-12.58) were the positive factors influencing IDUs' access to MMT.However,being married (OR=0.38,95％CI:0.20-0.72) or being employed (OR=0.01,95％CI:0.00-0.02) were the negative factors influencing IDUs' access to MMT.Conclusion The proportion of HIV infected IDUs who received MMT in ART clinics was still very low in the two counties,targeted intervention measures should be taken to increase the MMT coverage,especially among those who are married or employed.