ObjectiveTo study the feasibility and reasonability of low-dose multi-slice CT(MSCT)with three dimensional rendering of the tendons of foot and ankle. The statistical methods including ANOVA and Kruskal-Wallis H was used. MethodsForty-five consecutive patients with fractures of foot and ankle were enrolled and evenly grouped into A (80 kV, 100 mAs), B(110 k V ,60 mAs) and C (130 kV,60 mAs).The MSCT scanning range was 6 slices of 1.0 mm. The CT value and standard deviation (SD) of the muscle and the CTDIvol were recorded. The image quality of volume rendering of the tendons was blindly evaluated.ResultsThe CT value of muscle in group A (71.6 ± 12.0) HU was significantly higher than group B [(66.8±9.2) HU, P=0.010]and C[(66. 1 ±7. 1) HU, P =0.004]. The SD average values were 11.9, 6. 1 and 7.0 HU for three groups, and there were significant differences among the three groups(F =37. 142, P=0. 0000). Group A had the highest SD value, group C had the lowest SD;CT1DIvol average value were (3.01 ± 0. 08) , (4. 63 ± 0. 11), (7.02 ± 0. 24) mGy respectively, which were significant different among the three groups (H =39. 185, P =0. 000). Group A had the lowest CTDIvol, while group C had the highest CTDIvol. Volume rendering of the tendons was evaluated as 2.3 ± 0. 5、3.7 ± 0. 5、4. 8 ±0. 4, and there were significant differences among the three groups (H = 72. 779, P = 0. 000). Group A had the worst VR images, while group C had the best VR images.All VR images in Group B were good for diagnosis. ConclusionThe protocol of 110 kV, 60 mAs, and 1 mm × 6 with three-dimensional volume rendering would be enough for evaluating the tendons of foot and ankle.

Objective To state and analyze collateral vessels in patients with cirrhosis and portal hypertension with multislice spiral CT (MSCT).Methods 203 cases of cirrhosis and portal hypertension were included in the study and undergone upper abdomen examination with MSCT.Results 612 collateral vessels were demonstrated in this group: lower esophageal varices in 175, paraesophageal varices in 49, including greatly dilated azygos or hemiazygos veins and showing mediastinal pseudotumors in 13, gastric fundic varices in 119, left gastricvarices in 105, gastrorenal shunts in 34, splenorenal shunts in 15, paravertebral varices in 16, reopened umbilical vein in 48, reopenedparaumbilical vein in 22, reopened umbilical vein and paraumbilical vein in 4, abdominal wall varices and caput medusa sigh in 12, portalvein cavernous transformation in 8, greatly dilated right posterior portal vein connecting the inferior vena cava in 4 and left gastric veindirectly connected with the left portal branch in 1. Conclusion MSCT can much more clearly demonstrate the collateral vessels in patients with cirrhosis and portal hypertension. An understanding of the varied appearances of acquired abnormalities of the portal venous system will allow more definitive diagnosis and help avoid false diagnosis of disease, and may play a significant role in making a clinical treatment plan.

Objective:To investigate the correlations of SOX17 gene polymorphisms at the rs1072737, rs9298506 and rs10958409 loci with sporadic intracranial aneurysm (IA) in patients from Anhui province. Methods:A case-control study was performed on 162 patients with sporadic ruptured IA admitted to our hospital from January 2017 to December 2020 and 182 age-matched controls from Inpatient or physical examination center at the same time-period. The genotype and allele frequencies of SOX17 gene at the rs1072737, rs9298506 and rs10958409 loci between the 2 groups were analyzed and compared to determine the influence of different genotypes and alleles in IA. According to gender, the subjects were divided into male and female subgroups; according to rupture of IA, the subjects were divided into ruptured and un-ruptured subgroups; the risk factors and protective factors for IA in these subgroups were verified. Results:There was no significant difference in genotype distributions at rs10958409 locus between the two groups ( P>0.05). The results of multivariate Logistic regression analysis indicated that GG+GT genotype ( OR=0.913, 95%CI: 0.845-0.990, P=0.031) and allele G ( OR=0.805, 95%CI: 0.718-0.932, P=0.029) at rs1072737 locus were independent protective factors for IA, and GG+AG genotype ( OR=1.043, 95%CI: 1.008-1.084, P=0.011) and allele G ( OR=1.003, 95%CI: 1.001-1.007, P=0.023) at rs9298506 locus were independent risk factors for IA. GG+GT genotype and G allele at rs1072737 locus were still risk factors for IA in both males and females ( P<0.05), while GG+AG genotype and G allele at rs9298506 locus were still protective factors for IA in both males and females ( P<0.05). There was no significant difference in in genotype distributions at rs1072737 and rs9298506 loci between ruptured subgroup and un-ruptured subgroup ( P>0.05). Conclusions:In Anhui province, GG+GT genotype (allele G) carriers in SOX17 gene at rs1072737 locus have a relatively low risk of IA, while GG+AG genotype (allele G) carriers in SOX17 gene at rs9298506 locus have a relatively high risk of IA. There is no correlation of SOX17 gene polymorphisms at rs1072737 and RS9298506 loci with rupture of IA.