0.05). 73.96% of eczema were taken place at the age of 1～6 months, 13.02% were at the age of 6 months to 2 years, and 13.61% were at the age of 2～3 years. The incidence of eczema is also relevant to feeding patterns, which is 62.23%, 23.08% and 14.79% respectively by breast-feeding, mixed feeding and artificial feeding. Some other factors that relevant to the onset of eczema also have been found in the study, such as constitution, weather, genetic background, and so on. Conclusion Feeding pattern, genetic background and some other factors were relevant to the onset of eczema.

AIM:To investigate the expression and function of store-operated calcium channels ( SOCC) in human circulating fibrocytes.METHODS:Peripheral blood mononuclear cells ( PBMCs) were isolated and cultured in ser-um-free media.After 7 d, the PBMCs differentiated into fibrocytes.RT-PCR and real-time PCR were performed to deter-mine the mRNA expression of ORAI1-3 and STIM1-2 in the fibrocytes.SOCC inhibitor SKF-96365 was used to elucidate the role of SOCC in the differentiation of fibrocytes.RESULTS:The results of real-time PCR showed that the mRNA ex-pression of ORAI1-3 and STIM1-2 was positive in cultured fibrocytes.SKF-96365 (10μmol/L) significantly inhibited the differentiation of fibrocytes.CONCLUSION:SOCC-related proteins ORAI1-3 and STIM1-2 are abundantly expressed in the fibrocytes, and may play an important role in the differentiation of these cells.