1.Analysis of IgM antibodies detection results of pathogens in 2 846 children with acute respiratory tract infection
Lili JIANG ; Ruifang WANG ; Haiqun ZHOU ; Guangyou WEI
Chongqing Medicine 2017;46(25):3569-3570,3573
Objective To understand the pathogens distribution situation in children with acute respiratory tract infection (ARTI) in Bozhou area.Methods A total of 2 846 children with ARTI in our hospital from April 2015 to March 2016 were enrolled to investigate the pathogens distribution.The indirect immunofluorescence assay was performed to detect adenovirus,influenza virus A,influenza virus B,respiratory syncytial virus,parainfluenza virus,mycoplasma pneumoniae,chlamydophila pneumoniae and legionella pneumophila in peripheral blood samples.Results Of all 2 846 cases,1 161 (40.8%) cases were the pathogen detection positive.Among them,the top 3 viruses of highest detection rates were mycoplasma pneumoniae(470,16.5 %),influenza virus A (252,8.9%) and respiratory syncytial virus (117,4.1%),and 79(2.8%) cases were mixed infection.With age increase,the pathogen detection rate showed the declining trend(x2 =20.724,P=0.000 1).The infections in infants and young children were dominated by respiratory syncytial virus(11.2 %),which in preschool and school children was dominated by mycoplasma pneumoniae(15.2 %-25.4 %).The pathogen detection rate was highest in winter (57.7 %),and lowest in summer (22.5 %).Conclusion The prevalence distribution of ARTI pathogens varies with age and seasons.The infection rate in infants and young children is higher than that in other age groups.Mycoplasma pneumoniae,influenza virus A and respiratory syncytial virus are the main pathogens causing ARTI in children of Bozhou area,winter and summer have ARTI high onset,it is notable to strengthen the prevention of infection.
2.Automated Assessment of Developmental Levels of Epiphysis by Support Vector Machine
Yahui WANG ; Zishen WANG ; Hua WEI ; Lei WAN ; Chongliang YING ; Guangyou ZHU
Journal of Forensic Medicine 2014;(6):422-426
Objective To realize the autom ated assessm ent of the levels of epiphysis of distal radius and ulna by support vector m achine (SVM). Methods The X-ray film s of the leftwrist jointswere taken from 140 teenagers aged from 11 to 19 years old as training sam ples. The levels of epiphysis of distal radius and ulnawere divided into five developm ental levels. Each level contained 28 sam ples. A nother 35 cas-eswere selected as independent verifying sam ples. SVM classification m odels of the five developm ental levels of epiphysis of distal radius and ulnawere established. The internal cross validationwas m ade by leave one out cross validation (LOOCV ),while the external validationwas m ade by histogram of orient-ed gradient (HOG), and then the accuracy (PA ) of testing resultswas calculated, respectively. Results The PA of SVM, LOOCV and HOG of distal radius epiphyseal levelwere 100%, 78.6%, and 82.8%, respec-tively;whereas the PA of SVM, LOOCV and HOGof distal ulna epiphyseal levelwere 100.0%, 80.0%and 88.6%, respectively. Conclusion The SVM -based autom atic m odels of the growth stage of distal ra-dius and ulna appear to have certain feasibility, and m ay provide a foundation for software developm ent of bone age assessm ent by forensic medicine.
3.Posterior short-segment instrumentation without fusion for treatment of thoracolumbar compression fractures
Daode LIU ; Ling ZHOU ; Rui ZHONG ; Chuanen WANG ; Zhibin FU ; Wei DAI ; Guangyou JIANG
Chinese Journal of Trauma 2013;29(8):749-752
Objective To investigate the clinical effect of posterior short-segment pedicle screw reduction and fixation without fusion in treatment of thoracolumbar mono-segmental compression fractures.Methods Thirty cases of thoracolumbar mono-segmental compression fractures admitted from January 2009 to February 2010 were assigned to single posterior pedicle screw fixation (screw group,n =15) and posterior pedicle screw fixation with posterolateral fusion (fusion group,n =15) according to random number table.Clinical results in the two groups were assessed based on Cobb' s angle,anterior vertebral body height ratio (%) and Oswestry disability index (ODI) before operation,after operation,prior to the removal of implant and at the latest follow-up.Results All the cases were followed up for average 24 months.Both operation time and blood loss were less in screw group than in fusion group [(76.58 ±12.67) min vs (116.29 ± 17.45) min,P < 0.01 ; (287.54 ± 30.76) ml vs (480.34 ± 100.54) ml,P <0.01],whereas there were no statistical differences between the two groups in aspects of Cobb' s angle and anterior vertebral body height ratio before and after operation,prior to the removal of implant as well as at the latest follow-up.Moreover,no statistical difference of ODI was noted between the two groups prior to the removal of implant and at the latest follow-up.Conclusion Posterior pedicle screw fixation without bone grafting achieves similar effects with pedicle screw fixation with bone grafting.