1.Diagnosis and treatment of renal peripelvic cysts
Guanghui LI ; Xingyi CHEN ; Guangming QIU
Chinese Journal of Urology 2001;0(04):-
ObjectiveTo study the diagnosis and treatment of peripelvic cysts.MethodsA view of the diagnosis and treatment of 14 cases and an evaluation of the different means of diagnosis and treatment were carried out.Results12 cases were followed up for 6~48 months post-operatively.11 cases were well recovered,with no reoccurrence or complication,and in 2 the high blood pressure dropped to normal whereas repeated urinary infection has been noted postoperatively in 1.ConclusionsB supersonic exam,KUB+IVU,CT exam are the most effective means to the diagnosis of this disease,CT exam being the first choice.Open renal cystectomy is indicated.
2.A study on factors influencing the prostate-specific antigen
Guanghui LI ; Guangming QIU ; Jiasun LU ; At ET
Chinese Journal of Urology 2001;0(06):-
Objective To study the factors that might influence the PSA-value. Methods Serum samples were collected from 165 cases of benign prostate hyperplasia (BPH),43 cases of prostate cancer (PCa) and 41 cases of chronic prostatitis (CP),both before and after digital rectal examination (DRE),cystoscope examination,indwelling catheterization and finasteride intake. Results In the BPH group,T-PSA elevated from (2.28?2.07)ng/ml to (4.77?5.23)ng/ml, P
3.Analysis reading trends of medical students
Weihua HE ; Zhicai CHEN ; Guangming QIU ; Qing YE ; Peng LIU ; Jieyun HUANG
Chinese Journal of Medical Education Research 2005;0(06):-
This paper analysed our library’s lending records from 2006 to 2007 and studied the reading trends and significance of medicial students.Some idea and advice were put forward in this paper.
4.Quantitative CT assessment for hepatic steatosis
Pengji GAO ; Tihong QIU ; Xisheng LENG ; Guangming LI ; Lei HUANG ; Dong WANG ; Jie GAO ; Zhao LI ; Jiye ZHU
Chinese Journal of General Surgery 2012;27(3):220-222
Objective To evaluate the role of CT in quantitative assessment for hepatic steatosis.Methods We retrospectively assessed 215 liver grafts used in orthotopic liver transplantation (LT) from January 2006 to December 2009.Pathology and CT data were reviewed.The correlation between liver steatosis level and CT value of the liver were analyzed.The ratio of liver-spleen,liver-descending aorta,liver-inferior vena cava were calculated. Results There were 52 steatosis grafts diagnosed by pathologist and the steatosis level was from 2.78% to 56.8%.The CT value of the liver,the ratio of liver-spleen,liverdescending aorta,liver-inferior vena cava was 41.3 ± 7.5 HU,0.89 ± 0.16,1.02 ± 0.16,1.04 ± 0.15,respectively.There were significant linear negative correlation between the steatosis level and the CT value,the ratio of liver-spleen,liver-descending aorta and liver-inferior vena cava. The correlation index was -0.881,-0.817,-0.951 and -0.948,respectively. Conclusions The CT value of the liver,the ratio of liver-spleen,liver-descending aorta and liver-inferior vena cava could be used to quantitatively evaluate liver steatosis.The ratio of liver-descending aorta was the most sensitive index.
5.Identification of Age-associated Proteins and Functional Alterations in Human Retinal Pigment Epithelium
Jin XIUXIU ; Liu JINGYANG ; Wang WEIPING ; Li JIANGFENG ; Liu GUANGMING ; Qiu RUIQI ; Yang MINGZHU ; Liu MENG ; Yang LIN ; Du XIAOFENG ; Lei BO
Genomics, Proteomics & Bioinformatics 2022;20(4):633-647
Retinal pigment epithelium(RPE)has essential functions,such as nourishing and sup-porting the neural retina,and is of vital importance in the pathogenesis of age-related retinal degen-eration.However,the exact molecular changes of RPE during aging remain poorly understood.Here,we isolated human primary RPE(hRPE)cells from 18 eye donors distributed over a wide age range(10-67 years old).A quantitative proteomic analysis was performed to analyze changes in their intracellular and secreted proteins.Age-group related subtypes and age-associated proteins were revealed and potential age-associated mechanisms were validated in ARPE-19 and hRPE cells.The results of proteomic data analysis and verifications suggest that RNF123-and RNF149-related protein ubiquitination plays an important role in protecting hRPE cells from oxidative damage dur-ing aging.In older hRPE cells,apoptotic signaling-related pathways were up-regulated,and endo-plasmic reticulum organization was down-regulated both in the intracellular and secreted proteomes.Our work paints a detailed molecular picture of hRPE cells during the aging process and provides new insights into the molecular characteristics of RPE during aging and under other related clinical retinal conditions.