1.Distribution and risk factors of thyroid cancer in China
Fen DONG ; Biao ZHANG ; Guangliang SHAN
China Oncology 2016;(1):47-52
Incidence of thyroid cancer has continuously increased in the last three decades globally. A similar trend of thyroid cancer incidence appeared in China. New cases and deaths of thyroid cancer in China accounted for 15.6% and 13.8% of the global new cases and deaths in 2012. The incidence in East China was the highest while that in Middle China was the lowest. Thyroid cancer was more common in urban areas than in rural counterparts. The incidence was substantially higher in female patients than male. Thyroid cancer occurred most commonly in middle age. Radiation exposure, iodine suffciency or deifciency, sex hormone and genetic mutations were risk factors for thyroid cancer. To prevent it, potassium iodide should be taken to prevent radiation fallout in nuclear accidents, unnecessary exposure to radiation from medical imaging is reduced, iodine surveillance system is improved and appropriate standards for iodized salt are established.
2.A Study on the awareness of HIV/AIDS and risk behaviors among migrant workers at construction sties in Beijing
Qian ZUO ; Huanbo XIAO ; Guangliang SHAN
Chinese Journal of AIDS & STD 2007;0(05):-
Objective To investigate the awareness of HIV/AIDS and risk behaviors among migrant workers at construction sites in Beijing. Methods The methods of cluster sampling was employed,a questionnaire survey was administered among 1000 migrant workers from two construction sites and a face-to-face interview with the informed consent was conducted in a limited scope.Results There was considerable disparity in the awareness of the routes of AIDS transmission;66.8% of the migrant workers were aware that the condom could reduce the risk of infection,but 51% of them had never used it.Only 2.3% of the migrant workers had sexual intercourse with female sex workers.Conclusion Although the migrant workers under survey have some basic knowledge on HIV/AIDS,their essential understanding was mostly vague,and financial condition have restricted to a great extent their risk behaviors.
3.Influencing factors of iron deficiency in 3 to 6 months-old infants in Dongcheng District of Beijing
Jing NAI ; Ning BEI ; Weiwei ZHANG ; Guangliang SHAN
Chinese Journal of Health Management 2013;(2):121-125
Objective To explore the prevalence of anemia,iron deficiency and iron deficient anemia (IDA),and to identify their risk factors in 3 to 6 months infants in Dongcheng District of Beijing.Methods All the 845 infants aged 3 to 6 months who received bacille calmette guerin (BCG) vaccine during December 2010 and October 2011 in Hepingli Hospital of Beijing were invited to complete the investigation.Data (months,gender,birth weight,birth height,etc) were collected through a questionnaire survey.Infants were tested for hemoglobin (Hb),mean corpuscular volume (MCV),mean corpuscular hemoglobin (MCH),mean corpuscular hemoglobin concentration (MCHC),serum ferritin (SF) and zinc protoporphyrin (ZPP) and mothers underwent measurement for Hb,SF and serum iron (SI).Descriptive epidemiology and non-conditional logistic regression model were used to analyze the prevalence of nutritional anemia.Results The prevalence of anemia,iron deficiency and IDA was 12.06%,7.38% and 2.11%,respectively.Non-conditional logistic regression analysis showed that the associated factor of anemia in infants was month age (vs.3-4 months age group,4-5 months age group:odds ratio (OR) =0.496,95% confidence interval (CI) 0.272-0.905 ; 5-6 months age group:OR =0.494,95% CI 0.234-1.043).The factors associated with iron deficiency were month age (vs.3-4 months age group,4-5 months age group:OR =0.539,95% CI 0.266-1.088 ; 5-6 months age group:OR =0.334,95% CI 0.125-0.891) and time of first breast-feeding (vs.the first day,the second day:OR =2.359,95% CI 1.191-4.675; the third day:OR =1.154,95% CI 0.450-2.963).Conclusions Our data show that iron nutrition in 3 to 6 months-old infants in Dongcheng District of Beijing was in good situation.The influencing factors of iron nutrition in infants may be month age and the time of first breast feeding.
4.Ultrasound-guided percutaneous ablation treatment for current hepatoblastoma: initial single-center experience
Pengliang LI ; Jia LUO ; Xiaoer ZHANG ; Baoxian LIU ; Luyao ZHOU ; Guangliang HUANG ; Quanyuan SHAN ; Xiaoyan XIE
Journal of Chinese Physician 2017;19(6):813-816
Objective To summarize the first experience with ultrasound-guided percutaneous ab lation treatment (PAT) for recurrent hepatoblastoma (HB) after liver resection in children.Methods From August 2013 to April 2015,PAT was used to treat 6 children with a total of 9 recurrent HB,including 5 patients with 8 tumors in the liver and 1 patient with 1 tumor in the lung.The mean size of ablated tumors was (1.5 ± 0.8) cm,and the tumor size range was 0.7 cm to 3.1 cm.Results Four patients were performed percutaneous radiofrequency ablation (RFA) for recurrent HB;and 2 patients were performed percutaneous ethanol injection (PEI).Ablation success was achieved in all patients (6/6,100%).The complete ablation rate after the first ablation session was 88.9% (8/9) on a tumor-by-tumor basis.Only 1 patient developed a fever with temperature > 39 ℃;it was resolved by conservative therapy.During the follow-up period of 5-30 months,3 patients died to tumor progression.The 1-and 2-year overall survival rates after ablation were 83.3% and 41.7%,respectively.Conclusions PAT is a safe and promising therapy for children with recurrent HB after liver resection,and further investigation in large-scale randomized clinical trials is required to determine its role in the treatment of this disease.
5.Core competency of doctors at tertiary public hospitals in regions of different income levels in China: a cross-sectional survey
Zitang HE ; Yue LI ; Yaoda HU ; Guojie ZHANG ; Li LI ; Jialin SUN ; Linzhi LUO ; Zhenlong WU ; Guangliang SHAN ; Shuyang ZHANG
Chinese Journal of Hospital Administration 2023;39(6):442-448
Objective:To explore the core competency of doctors in tertiary public hospitals in regions of different income levels in China, and provide reference for promoting such competency and related policy formulation.Methods:Using multi-stage stratified cluster sampling method, 195 tertiary public hospitals in 16 provinces of China were selected from November 2021 to March 2022. 200 doctors were sampled from each hospital. A self-designed questionnaire was used to investigate the status of doctors′ core competencies, as well as the status of their postgraduate medical education and continuing medical education. According to the per capita gross regional product of each province in China Statistical Yearbook 2022, each province was divided into high, middle and low income regions, and the questionnaire data were descriptively analyzed, while χ2 test was used to compare the differences between groups. Results:A total of 32 673 valid questionnaires were collected. There were 12 135 doctors (37.14%) in China who had received comprehensive education and training of core competency in all dimensions. Among the dimensions of self-rated core competency of the surveyed doctors, there were 10 019 doctors (30.66%) with insufficient teaching ability and 438 (1.34%) with insufficient professional quality, and there was no significant difference between regions ( P>0.05). There were 2 385 (27.08%), 2 528 (27.55%) and 3 646 (24.82%) doctors in high-, middle- and low-income regions with insufficient lifelong learning ability, respectively. The proportion of doctors in middle- and high-income regions was higher than that in low-income ones ( P<0.05). There were 1 317 (15.57%), 1 290 (14.06%) and 2 719 (18.51%) doctors with insufficient knowledge and skills in high-, middle- and low-income areas, respectively. The proportion of doctors in low-income regions was higher than that in middle- and high-income regions ( P<0.05). The proportion of doctors who did not receive any kind of postgraduate medical education or continuing medical education in low-income regions was 7.33% (1 077 people), higher than that in high-income and middle- income ones ( P<0.05); 50.44% (4 442 people) of surveyed doctors in high-income regions believed that for standardized training of resident physicians (hereinafter referred to as residential training), the clinical teachers were " overworked to take this job", which was higher than that in middle- and low-income regions ( P<0.001); In middle-income regions, 46.16% (4 235 people) and 43.46% (3 987 people) believed that the salary residents and specialized physicians in standardized training (hereinafter referred to as specialized training) was too low, while 42.47% (3 897 people) and 30.44% (2 793 people) believed that the clinical practice opportunities of students were limited, both of which were higher than those in high-income and low-income regions ( P<0.001); 34.91% (5 128 people) of surveyed doctors in low-income regions believed that the investment was insufficient for training bases of residential training, 27.81% (4 085 people) of those held that training bases for specialized training were unevenly distributed, and 33.19% (4 876 people) of those held that continuing medical education was plagued by " insufficient promotion coverage, and insufficient opportunities for primary doctors", all of which being higher than those in high- and middle-income regions ( P<0.001). Conclusions:There is an obvious need to improve the core competence of doctors in the teaching ability dimension of tertiary public hospitals in China, especially in middle- and high-income regions for lifelong learning, and in low-income regions for knowledge and skills; There are differences between postgraduate medical education and continuing medical education systems in regions of different income levels in China. It is necessary to improve the competency oriented postgraduate medical education and continuing medical education systems.
6.Quality metrics and outcomes among critically ill patients in China: results of the national clinical quality control indicators for critical care medicine survey 2015-2019
Xi RUI ; Fen DONG ; Xudong MA ; Longxiang SU ; Guangliang SHAN ; Yanhong GUO ; Yun LONG ; Dawei LIU ; Xiang ZHOU
Chinese Medical Journal 2022;135(9):1064-1075
Background::It is crucial to improve the quality of care provided to ICU patient, therefore a national survey of the medical quality of intensive care units (ICUs) was conducted to analyze adherence to quality metrics and outcomes among critically ill patients in China from 2015 to 2019.Methods::This was an ICU-level study based on a 15-indicator online survey conducted in China. Considering that ICU care quality may vary between secondary and tertiary hospitals, direct standardization was adopted to compare the rates of ICU quality indicators among provinces/regions. Multivariate analysis was performed to identify potential factors for in-hospital mortality and factors related to ventilator-associated pneumonia (VAP), catheter-related bloodstream infections (CRBSIs), and catheter-associated urinary tract infections (CAUTIs).Results::From the survey, the proportions of structural indicators were 1.83% for the number of ICU inpatients relative to the total number of inpatients, 1.44% for ICU bed occupancy relative to the total inpatient bed occupancy, and 51.08% for inpatients with Acute Physiology and Chronic Health Evaluation II scores ≥15. The proportions of procedural indicators were 74.37% and 76.60% for 3-hour and 6-hour surviving sepsis campaign bundle compliance, respectively, 62.93% for microbiology detection, 58.24% for deep vein thrombosis prophylaxis, 1.49% for unplanned endotracheal extubations, 1.99% for extubated inpatients reintubated within 48 hours, 6.38% for unplanned transfer to the ICU, and 1.20% for 48-hour ICU readmission. The proportions of outcome indicators were 1.28‰ for VAP, 3.06‰ for CRBSI, 3.65‰ for CAUTI, and 10.19% for in-hospital mortality. Although the indicators varied greatly across provinces and regions, the treatment level of ICUs in China has been stable and improved based on various quality control indicators in the past 5 years. The overall mortality rate has dropped from 10.19% to approximately 8%.Conclusions::The quality indicators of medical care in China’s ICUs are heterogeneous, which is reflected in geographic disparities and grades of hospitals. This study is of great significance for improving the homogeneity of ICUs in China.
7.Principles and practice on cohort study of general population in Beijing, Tianjin and Hebei province
Chinese Journal of Epidemiology 2021;42(8):1493-1497
Cohort study has emerged as an essential tool for gaining knowledge about risk factors and prevention of diseases. The studies related to cohort population have been progressing more than 60 years in our country, while different types and numbers in cohort studies have increased dramatically with the key programs special for the cohort study were approved firstly by the Ministry of Science and Technology of China since 2016. With typical study design, cohort study is currently needed to use the latest multidisciplinary resources and methods in order to be more systematic and accurate on association analysis and causal inference of diseases. For the cohort study of general population in Beijing, Tianjin and Hebei province, the core principles and concepts of study design, progress and the key issues targeting implementation were introduced. In addition, opportunities, bottlenecks and solutions facing us were also explored.
8.Trends of overweight and obesity in Yi people between 1996 and 2007: an Yi migrant study.
GuangLiang SHAN ; DaYing WEI ; ChunXiu WANG ; JianHua ZHANG ; Bin WANG ; MingJu MA ; Li PAN ; Tao YU ; Fang XUE ; ZhengLai WU
Biomedical and Environmental Sciences 2011;24(5):467-474
OBJECTIVETo evaluate trends of overweight and obesity prevalence between 1996 and 2007 in Yi farmers and Yi migrants.
METHODSAn Yi migrant study was conducted in Liangshan Yi Autonomous Prefecture, Sichuan Province, China from 1996 to 2007. Data were collected with identical methods, including standardized questionnaire and body measurements.
RESULTSAge- and sex-specific body mass index (BMI) significantly increased from 20.02 in 1996 to 22.36 in 2007, among Yi farmers, which was significantly different from those among Yi migrants (23.67 in 2007 and 20.90 in 1996) (P<0.05). Prevalence of obesity rose from 1.21 % in 1996 to 4.55 % in 2007 (OR=1.15, P<0.001) in Yi migrants, while that in Yi farmers from none in 1996 to 0.12 % in 2007 (P>0.05). Prevalence of overweight rose significantly to 26.24 % in 2007 from 17.24 % in 1996 (OR=1.06, P<0.001) in Yi migrants, while that in Yi farmers from 1.29 % in 1996 to 4.45 % in 2007 (OR=1.14, P>0.001). Yi migrants appeared to have a 5.52-fold higher risk on developing overweight and obesity than Yi farmers have.
CONCLUSIONThe Yi migrants had a steeper increase of overweight with year and consequently caused more obesity. Change in lifestyle may contribute most likely to higher prevalence of overweight and obesity in Yi migrants.
Adult ; Agriculture ; statistics & numerical data ; trends ; Body Mass Index ; China ; epidemiology ; Female ; Humans ; Male ; Middle Aged ; Obesity ; epidemiology ; Overweight ; epidemiology ; Prevalence ; Rural Population ; statistics & numerical data ; Transients and Migrants ; statistics & numerical data ; Urban Population ; statistics & numerical data ; Young Adult
9.Association between socioeconomic status and overweight/obesity in Yi people, Sichuan province
Ye WANG ; Li PAN ; Shaoping WAN ; Huowuli YI ; Fang YANG ; Huijing HE ; Zheng LI ; Jia ZHANG ; Zhengping YONG ; Guangliang SHAN
Chinese Journal of Epidemiology 2020;41(3):315-319
Objective:To explore the association between socioeconomic status (SES) and overweight/obesity in Yi people in Sichuan province.Methods:A cross-sectional study was conducted in Liangshan Yi Autonomous Prefecture in 2015. Stratified cluster sampling method was used to enroll Yi farmers and rural-to-urban Yi migrants aged 20-80 years. SES was measured by education level, personal annual income, and compound SES index. Unconditional logistic regression models were used to determine the association between SES and overweight/obesity (BMI≥24.0 kg/m 2). Results:1 894 Yi farmers and 1 162 rural-to urban migrants were included in the analysis. After adjustment for age, smoking, drinking and physical activity, compared with illiteracy, OR for farmer males with higher education level (primary or junior school, senior high school or higher) were 1.71 (95 %CI: 1.13-2.58) and 4.15 (95 %CI: 2.10-8.22). Compared with lower income group (<5 000 CNY/y), the higher income group had increased risk ( OR=1.66, 95 %CI: 1.12-2.44). For farmer males with medium and high SES level, the risk of overweight/obesity were 1.65 (95 %CI: 1.02-2.67) and 3.26 (95 %CI: 1.97-5.42) compared with low level of SES. For farmer females, the risk increased with the higher income, with OR as 1.49 (95 %CI: 1.10-2.02). Compared with low SES level, farmer females with medium level of SES was associated with 1.47 (95 %CI: 1.11-1.95) times higher risk of overweight/obesity. In Yi migrants, the association between SES and overweight/obesity was not found. Conclusion:Socioeconomic status was positively associated with overweight/obesity only in Yi farmers.
10.Application and Inspiration of Information System used in National Health and Nutrition Examination Survey of America
Ji TU ; Huijing HE ; Yaoda HU ; Li PAN ; Guangliang SHAN
Chinese Journal of Epidemiology 2022;43(7):1127-1133
The National Health and Nutrition Examination Survey (NHANES) of America has been running for more than 60 years and has achieved many significant achievements with international influence. The application of modern information technologies in NHANES provides a supplementary tool for the project's high quality and refined implementation. This paper introduces the information system of NHANES from seven aspects: project management, survey participant interview, physical examination, laboratory examination, field follow-up, data sharing, and social services. The construction and application prospects of the China National Health Survey Information System, suitable for China's native conditions, are also discussed in this article.