1.Comparison of the image manifestation and sensitivity of X ray, CT and MRI in pulmonary cancer of mediastinal type
Chinese Journal of Primary Medicine and Pharmacy 2013;20(13):1977-1979
Objective To explore the image manifestation and sensitivity of X ray,CT and MRI in pulmonary cancer of mediastinal type.Methods The clinical data of 31 patients with pulmonary cancer of mediastinal type were retrospectively analyzed.All 31 patients underwent X ray and plaiu CT scan,and 7 cases of them also underwent enhanced CT scan.21 patients underwent plain MRI and 3 of them also underwent enhanced MRI scan.The image manifestation and sensitivity of X ray,CT and MRI were analyzed.Results In 31 cases,there were 18 cases of central type lung cancer and 13 cases of peripheral lung cancer which confirmed by operation.The common manifestation of X ray in central type and peripheral lung cancer showed that mediastinal became wider and the trachea was pushed.In CT manifestation,the margin of tumor was irregular.Tumors demonstrated sublobe,sentus and lymphadenectasis of mediastinal lymph node.Some patients accompanied by obstructive pneumonia and atelectasis.MRI could accurately display tumor invading in the chest wall,pleura and thoracic goiter beside CT image manifestation.The clinical diagnostic sensitivity of X ray,MRI and CT were 88%,100% and 100% respectively.The sensitivity of CT and MRI were significantly higher than that X ray (x2 =12.251,P < 0.05).Conclusion The pulmonary cancer of mediastinal type is easily misdiagnosed.The clinical diagnosis accuracy can enhance by clinical symptoms combined with image manifestation of X ray,CT and MRI.
2.The effects of a changed second stage of labor duration on the maternal and neonatal outcomes
Chongqing Medicine 2016;45(27):3796-3798
Objective To investigate the influence of the different second stage of labor duration on the maternal and neo‐natal outcomes .Methods Data were retrospectively analyzed from 201 nulliparous women delivering a singleton infant in cephalic presentation without labor analgesia hospitalized in our hospital between January 2012 and May 2015 ,whose second stage pro‐gressed beyond 2 hours .They were divided into observation group and control group according to different second stage of labor du‐ration ,and cases with a second stage of labor duration of three hours were in the observation group (163 cases) ,and those within two hours were in the control group (38 cases) .Results Whether the limit of the second stage of labor duration of 2 hours ,or 3 hours ,the risk of postpartum hemorrhage ,postpartum fever ,urinary retention and neonatal asphyxia ,admission to the neonatology department in two groups were not significantly different(P>0 .05) .However ,there was significance difference in the rate of soft birth canal laceration(72 cases in the observation group) ,poor wound healing (0 case in the observation group and 3 cases in the control group ,P<0 .05) .Conclusion a second stage of labor duration of 3 hours could reduce the rate of cesarean section ,and with no increase in severe adverse maternal and neonatal outcomes .
3.Preoperative magnetic resonance imaging evaluation of knee cartilage injury
Guanghong LIU ; Bing ZHANG ; Hui ZHANG
Chinese Journal of Orthopaedic Trauma 2015;17(8):699-703
Objective To explore clinical value of magnetic resonance imaging (MRI) in preoperative risk assessment and choice of operation scheme for knee cartilage injury.Methods A retrospective study was conducted of the 69 cases of knee cartilage injury which had been confirmed by surgery between January 2013 and June 2014.They were 29 males and 40 females,aged from 15 to 76 years (average,46.9 years).All cases underwent preoperative 1.5 T MRI by a special diagnostic instrument for limbs.The injury was assessed after MRI according to the Outerbridge criteria to evaluate surgical risks and choose an appropriate operation scheme (drilling,micro-fracture or autoallergic cartilage grafting).The intraoperative observations were compared with the preoperative images.Results MRI found in the 69 patients 345 cartilage surfaces,of which 208 were abnormal.Of the abnormal ones,75 (21.7%) were grade Ⅰ which presented with intact or slightly eminent contour and dots or patches of low or high signals in the cartilage;39 (11.3%) were grade Ⅱ which presented with thinned cartilage,defects < 50% of the full thickness,or (and) indented or wavy cartilage surface,dots or patches of low or high signals in the cartilage,and dropsy signals in cavity;43 (12.5%) were grade Ⅲ which obviously thinned cartilage,defects > 50% of the full thickness,and massive dropsy signals in cavity;51 (14.8%) were grade Ⅳ which presented with full thickness defects of cartilage,subchondral bone exposure beneath the defcts,and abnormal adjacent tissues.The preoperative findings were in agreement with what were observed during surgery in terms of number and extent of cartilage injury.Conclusion Because MRI can exactly display knee cartilage injury in terms of location,degree,and size,it provides solid evidence for preoperative risk assessment and choice of operation scheme for knee cartilage injury.
4.Analysis of lumbar bone mineral density of 575 individuals by QCT examination
Wenqing CHEN ; Ningjiang SHEN ; Guanghong LIU
Orthopedic Journal of China 2006;0(06):-
[Objective]To analyze the relation of age and sex with the incidence of physical examinees with osteoporosis and low bone mass of vertebras.[Method]Quantitative CT(QCT) was used to examine and analyze the lumbar bone mineral density in 575 physical examinees.The data was analyzed by statistical software SAS 9.0.[Result]Bone mineral density(BMD)decreased with age after 50 years old.The occurrence rates of osteoporosis were 56.34% for females at 50-59 years,87.80% at 60-69 years,97.22% at 70-79 years and 100% at 80-89 years,25.44% for males at 50-59 years,50.64% at 60-69 years,66.66% at 70-79 years,and 90.91% at 80-89 years.[Conclusion]The incidence of osteoporosis is positively related with the age.The occurrence rate of osteoporosis increases with increasing age.It is obviously higher in females than in males.
5.MRI Study the Acute Disseminated Encephalomyelitis(ADE) Using FastFluid-attenuated Inversion Recovery Pulse Sequence
Changqing LI ; Guanghong LIU ; Jianjun LI
Journal of Practical Radiology 2001;0(08):-
Objective To evaluate the clinical application of fast fluid-attenuated inversion recovery(FLAIR) pulse sequence in MRI study of ADE.Methods Thirty cases with ADE were studied with fast FLAIR sequence and T 2 weighted spinecho sequence.The results were compared in terms of image quality.Results We found the fast-FLAIR could suppress CSF signal effectively,and more lesions were displayed on FLAIR images than on turbo SE T 2-weighted images.The extent of the lesions and the contrast between lesions and normal brain tissue were demonstrated better with fast-FLAIR sequence.Conclusion The lesions in ADE are demonstrated on fast-FLAIR sequence better than on turbo SE T 2 weighted sequence and FAST-flair could be a complementing modality to display lesions in ADE.
6.Targeted monitor and comprehensive intervention of multidrug-resistant organism infection in a general hospital
Yuling LIU ; Guanghong SHI ; Zhen TIAN
Chinese Journal of Infection Control 2015;(6):383-385,398
Objective To evaluate the occurrence of multidrug-resistant organism (MDRO)infection in a general hospital,and take effective comprehensive intervention measures,so as to reduce MDRO infection.Methods Targeted monitoring on MDROs was performed from October 2012 to December 2013,comprehensive intervention measures were conducted,the occurrence of MDRO infection before and after intervention was compared.Results A total of 62 384 pa-tients were investigated,17.91%(n=11 176)were sent specimens for pathogen culture,606 times of culture for patients’ specimens were detected MDROs,292(0.47%)cases were MDRO healthcare-associated infection(HAI),314 were com-munity-acquired infection or colonization.MDRO infection case rate decreased from 0.65%(75/11 603)before intervention to 0.26%(36/13 875)after intervention (χ2 =21.08,P <0.05).Conclusion Comprehensive intervention measures can effectively reduce the occurrence of MDRO HAI.
7.Diagnosis of osteoporosis by vertebral bone mineral density measurement with quantitative computed tomography
Ningjiang SHEN ; Yibo LI ; Wenqing CHEN ; Guanghong LIU
Orthopedic Journal of China 2008;16(11):826-828
[Objective] To evaluate the clinical value of diagnosing osteoporosis with vertebra bone mineral density(BMD) by measurement with quantitative computed tomography (QCT) . [ Method] BMD in of lumbar vertebrae (L<,1~4>)were measured by QCT in 53 healthy middleaged persons or elderly persons (group A) and 68 osteoporosis patients ( groupB) . [Result] BMD in group A declined obviously as age increasing with significant differences (P<0. 01) . In group B,all 68 patients showed osteoporosis according to the diagnostic standard of BMD≤x -2. OSD. Sixty patients showed osteoporosis ifthe diagnostic standard was set to BMD ≤ x -2. 5SD. The BMD values of different age group was lower than the bone quantityblock values. [Conclusion] As a method for diagnosing osteoporosis, QCT has advantages of high sensitation, being precise,being reproducible and is easy for applying. It would be more practical and could decrease mis - diagnosing if the diagnosticstandard was BMD≤x-2.OSD.
8.The Changes of Cerebrovascular Dynamic Indexes under the Condition of Atherosclerosis in Rabbits
Jing WANG ; Yinmian SHI ; Xixi LI ; Zhaorong LIU ; Guanghong DING
Academic Journal of Second Military Medical University 1985;0(06):-
In the experiment of atherosclerosis, the change of the cerebrovascular dynamic indexes (CVDI) was observed. In the atherosclerosis group, the values of carotid artery's mean flow (Qmcan), mean velocity (Vmcan), maximal velocity (Vmax), minimal velocity (Vmin) and cerebrovascular compliance for zero pressure (CO) were significantly decreased (P
9.The evaluation of Xpert MTB/RIF for the diagnosis of tuberculous meningitis
Ruixue ZHANG ; Yin LONG ; Guodong FENG ; Hao LIU ; Guanghong BAI ; Xiuli XU ; Xiaodong CHENG ; Xiaoke HAO ; Jiayun LIU
Chinese Journal of Laboratory Medicine 2016;39(6):442-447
Objective To evaluate the diagnostic performance of Xpert MTB/RIF for the diagnosis of tuberculous meningitis (TBM).Methods This was a prospective, single center clinical trial.A total of 116 consecutive patients with suspected meningitis who were admitted to Xijing Hospital from October 2013 to June 2015 were recruited.Mycobacterium tuberculosis ( MTB) and rifampicin ( RIF) resistance mutations in 1 ml cerebrospinal fluid ( CSF) were detected with Xpert MTB/RIF and the remaining sample was tested by Ziehl-Neelsen staining , MGIT960 liquid culture and other laboratory tests .And the enrolled patients were grouped according to the 2010 South African expert consensus .The diagnostic performance of Xpert MTB/RIF was evaluated by comparing against clinical score >5 points and MGIT960 liquid culture as reference standards respectively .The comparison was performed using a χ2 test or Fisher′s exact test for categorical variables and a nonparametric rank sum test for continuous variables .Results Among the enrolled 116 subjects, 23 subjects were diagnosed as definite-TBM by MGIT960 liquid culture, 16 subjects were classified as probable TBM , 27 subjects were classified as possible TBM , and 50 subjects were classified as non-TBM.When clinical score >5 points was used as a reference standard , the sensitivity of Xpert MTB/RIF (39.4%) was comparable with that of MGIT960 liquid culture (34.8%) (χ2 =0.292, P=0.589), and significantly better than that of Ziehl-Neelsen staining (9.9%) (χ2 =16.500, 12.771, P<0.001). No significant differences were found among the specificities of Xpert MTB /RIF, MGIT960 liquid culture and Ziehl-Neelsen staining ( 98.0%, 100.0% vs 98.0%, χ2 =1.014, P=0.602 ) .When tested against MGIT960 liquid culture as a reference standard , the sensitivity of Xpert MTB/RIF was 91.3%. Conclusions Xpert MTB/RIF is a rapid and specific method to detect MTB and RIF resistance in CSF .It exhibits a good rule in value for the diagnosis of TBM and a comparable sensitivity with MGIT 960 liquid culture, thus it can be used as the initial method for the diagnosis of tuberculous meningitis .
10.Research and development on the dynamic system for detecting the force of acupuncture needle during the acupuncture process in the clinical practice of traditional Chinese medicine.
Guanghong DING ; Xueyong SHEN ; Jianhua DAI ; Hui LIU ; Wei YAO ; Xin'an LI
Journal of Biomedical Engineering 2003;20(1):121-124
Manipulations are essential to the acupuncture curative effect. With the technique limited, the researches on acupuncture manipulations can only be carried out with respect to the senses and experience of doctors and patients, thus seriously impeding the modernization and internationalization of acupuncture. Both the modern integration technology of transducer and the biomechanical principles are applied to develop a detection system that can measure the interaction force between the manipulator and the manipulated patient on the needle at each kind of manipulation. Through clinical practice, the force waveforms acting on needle with the manipulations of symmetrical twirling-rotating and symmetrical lifting-inserting were recorded so as to realize the quantitative, objective and real-time detection of the force during the acupuncture process, which provided a new experimentation means and analysis method for the improvement of clinical curative effect and quantitative research of acupuncture and meridians.
Acupuncture
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instrumentation
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Biosensing Techniques
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instrumentation
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Equipment Design
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Humans
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Mechanics
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Medicine, Chinese Traditional
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Needles
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Software
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Software Design