1.Expanding Power Supply System in Mobile Field Hospital
Jun WANG ; Xiaodong ZHENG ; Qingchao YANG ; Guangan SONG
Chinese Medical Equipment Journal 2004;0(09):-
Objective To analyze and solve problems in spreading out the power supply system in mobile field hospital during the earthquake relief.Methods According to the layout of the mobile field hospital and the need of electrical power,the sketch map of electric circuit was drawn out and spread with load as less as possible.Results Current supply and its safety in mobile field hospital are guaranteed.Conclusion This kind of power supply system meets the requirement of the mobile field hospital in emergent rescue tasks.
2.The Effect of "Xingnao Kaiqiao" Acupuncture on the Expression of Peroxiredoxin VI in the Ischemin Cortex of Rats
Huiyan SHI ; Guangan WANG ; Jingrong WEN ; Xiaofeng ZHAO ; Shu WANG ; Xuemin SHI ;
Journal of Medical Research 2009;38(8):22-24
Objective To investigate and observe the expression of Peroxiredoxin Ⅵ in iechemia cortex of rats and the intervention effect of Xingnao Kaiqiao Acupuncture(XKA) therapy. Methods Through western blotting,we detected the expression of Peroxiredoxin Ⅵ in xingnao kaiqiao group , comparison group, model group and sham operation group in middle cerebral artery occlusion (MCAO)model of rats. Results At 6h, the expression of Peroxiredoxin Ⅵ in xingnao kaiqiao group , comparison group and sham operation group was increased than that in moddle group,of which Xingnao Kaiqiao group increased obviously(P < 0.05). At 24h, as compared with modlegroup, the expression of Peroxiredoxin Ⅵ in xingnao kaiqiao group and comparison group increased significantly (P < 0.05). Conclusion Xingnao Kaiqiao Acupuncture therapy could raise the expression of Peroxiredoxin Ⅵ in focal cerebral ischemia of rats, and the effect is better that of traditional acupuncture therapy in the earlier period.It is benefit to elevating the ability of antioxygen of focal cerebral ischemia of rats.
3.Ancient Literature Analysis and Modern Clinical Application of Famous Classical Prescription Zhishi Xiebai Guizhi Tang
Xiaozhang TANG ; Hongxia LIU ; Renwen CHEN ; Xiaodong WANG ; Dasheng LIN
Chinese Journal of Experimental Traditional Medical Formulae 2023;29(8):174-185
Zhishi Xiebai Guizhi Tang, derived from Synopsis of the Golden Chamber (《金匮要略》, Han dynasty, ZHANG Zhongjing), is a famous classical prescription commonly used for chest impediment. By means of bibliometrics, the authors collected 63 ancient Chinese medical books related to Zhishi Xiebai Guizhi Tang and screened 36 effective books for statistical analysis of the historical origin, composition, main indications, dosage, processing, decocting method and other aspects of the prescription. The findings revealed that Zhishi Xiebai Guizhi Tang was composed of five medicinal herbs, namely, Aurantii Fructus Immaturus, Allii Macrostemonis Bulbus, Cinnamomi Ramulus, Magnoliae Officinalis Cortex, and Trichosanthis Fructus, with the function of activating Yang, dissipating mass, dispelling phlegm and lowering Qi. The prescription was mainly used to treat chest impediment, chest fullness, chest pain, wheezing, coughing and shortness of breath caused by suppressed Yang Qi, stagnant heart Qi, stagnant phlegm and stasis, and phlegm evil blocking heart, chest or lungs. Additionally, it was found that there were 70 modern literature recording the clinical applications of Zhishi Xiebai Guizhi Tang, and the main system diseases treated were circulatory system (51, 72.85%), endocrine system (4, 5.7%), respiratory system (9, 12.85%) and digestive system (6, 8.57%), of which circulatory system is dominated by coronary heart disease (chest impediment in traditional Chinese medicine). The involved medical syndrome types mainly included internal obstruction of phlegm heat and turbidity, obstruction of phlegm turbidity and stasis, congealing cold, phlegm, stasis and Qi stagnation, chest Yang depression and combined phlegm and stasis. Ancient medical records and modern clinical application are the keys to ensure the safety and effectiveness of famous classical prescriptions and compound preparations. Therefore, this paper sorted and mined ancient medical books of Zhishi Xiebai Guizhi Tang and statistically analyzed its modern clinical application, aiming to provide a literature reference for the research and development of new drugs and clinical application of the prescription.
4.The impact of impulsivity on digital addiction tendencies and related factors in Wilson disease patients
Jieru KE ; Yajie CHENG ; Gongqiang WANG ; Ping JIN ; Xinfeng MA ; Kang LIN ; Guangan TONG ; Qunrong YE ; Yongzhu HAN
Chinese Journal of Nervous and Mental Diseases 2024;50(7):423-429
Objective To explore the influence of impulsivity on digital addiction tendencies in patients with Wilson disease(WD)and its related factors.Methods A total of 66 patients with WD were included in the study which were divided into neurological WD group(42 cases)and hepatic WD group(24 cases)according to clinical manifestations.Sixty-six WD patients were included as the study subjects,including 24 cases of hepatic WD and 42 cases of neurological WD.The Chinese version of the Barratt impulsiveness scale(BIS-11-C)was used to assess patients'impulsiveness.Mobile phone addiction index(MPAI)evaluates the degree of dependence on mobile phone use.Cranial MRI was used to examine the location and cumulative frequency of the diseased brain region.Results Among the 66 WD patients,45 cases(68.2% )had the tendency of digital addiction,including 35 cases(53.0% )in the neurological WD group and 10 cases(15.2% )in the hepatic WD group.There was a statistically significant difference in the proportion of the two types of WD patients(P=0.001).The scores of BIS-11-C and MPAI scales in neurological WD group were higher than those in hepatic WD group(P<0.05).The out-of-control score in the MPAI scale is positively correlated with the attention impulsivity score(r=0.499,P=0.001),motor impulsivity score(r=0.553,P=0.001),unplanned impulsivity score(r=0.535,P=0.001),and impulse control score(r=0.653,P=0.001)in the BIS-11-C scale.Linear regression analysis showed a correlation between attention impulsivity score and frontal lobe lesions(B=-1.634,P=0.018).There was a correlation between loss of control score and frontal lobe lesions(B=-3.609,P=0.023).The withdrawal score was associated with the thalamus lesions(B=-5.047,P=0.007)and frontal lobe lesions(B=-2.204,P=0.024).Avoidance score was associated with parietal lobe lesions(B=-1.867,P=0.032).The low efficacy score was associated with the putamen lesions(B=-1.789,P=0.016)and frontal lobe lesions(B=-1.592,P=0.044).Conclusion Neurological WD patients have higher tendency of digital addiction than hepatic WD patients and the tendency of digital addiction is related to impulsivity.The digital addiction tendency of WD patients may be related to impulse control disorders caused by lesions in multiple brain regions such as the putamen,thalamus,and frontal lobe.
5.Two-stage retrograde hybrid repair in the surgical treatment of acute aortic dissection complicated with distal malperfusion syndrome
Peng YANG ; Yi XIE ; Yu LIU ; Yu ZHANG ; Qianlei LANG ; Wenfan LI ; Chenhao WANG ; Zhenghua XIAO ; Jia HU
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2024;31(04):585-593
Objective To evaluate the clinical efficacy of two-stage retrograde hybrid repair for acute aortic dissection involving the aortic arch complicated with distal malperfusion syndrome. Methods From May 2019 to December 2022, the patients presented with acute aortic dissection involving the aortic arch complicated with distal malperfusion syndrome treated in the Department of Cardiovascular Surgery of West China Hospital, Sichuan University were enrolled. After preoperative evaluation, all patients underwent priority emergency interventional surgery to improve distal malperfusion, and then underwent two-stage hybrid surgery to repair proximal aortic lesions. The perioperative clinical and imaging data were retrospectively analyzed. Results Five patients were collected, including 4 males and 1 female, with a median age of 58 years. The main manifestations were lower limb ischemia and renal insufficiency in 3 patients, and poor intestinal perfusion in 2 patients. All patients were given priority to interventional surgery to implant graft stents or bare stents and necessary branch artery intervention, and then successfully performed two-stage hybrid surgery, including type Ⅰhybrid surgery for 2 patients, type Ⅱ hybrid surgery for 1 patient and type Ⅲ hybrid surgery for the other 2 patients, with a success rate of 100.0%. All patients were discharged successfully, and the function of the organs with poor perfusion returned to normal. Only 1 patient recovered to grade 4 muscle strength of the diseased lower limbs upon discharge. No adverse events such as amputation, exploratory laparotomy and intestinal resection or long-term hemodialysis occurred. Conclusion The application of two-stage retrograde hybrid repair in the surgical treatment of acute aortic dissection involving the aortic arch complicated with distal malperfusion syndrome is safe and effective, and is helpful to improve the perioperative survival rate, and clinical outcomes of such patients.