Present research intended to investigate the mediating role of affectivity in the association between Emotional Intelligence (EI) and life satisfaction. Sample of the study was consisted of N=300 medical students. The ability emotional intelligence scale, positive and negative affectivity schedule, and satisfaction with life scale were used to operationalize the constructs of current study. Results of the present study inveterate the proposed hypotheses as life satisfaction had significant positive relationship with positive affect whereas it was significantly and negatively co-related with negative affect. Meditational analysis revealed that EI had significant indirect effect on satisfaction with life through negative and positive affectivity. This study contributed to the literature of association between emotional intelligence and subjective wellbeing in which both component of subjected wellbeing i.e., cognitive component and affective component were studied.