Objective Investigate the effect of recombinant human growth hormone on large area burn with severely inhalation injury. Methods Forty cases of large area burn with severely inhalation injury were divided randomly into two groups, 20 in control group and 20 in rhGH group. The indexes of nutritional status (including MAMC,Hb,total protein,albumin and so far),healing time of burn wound,and the time of mechanical ventilation were recorded and compared between two groups. Results The nutritional status showed no difference between two groups before treatment,and was significantly better in rhGH group after treatment.The healing time of autologous skin pulp grafting and donor site,the time of mechanical ventilation and the length of hospital stay were significantly shorter in rhGH group patients than control group.Conclusion rhGH can enhance the wound healing rate,improve the nutritional status of patients with mechanical ventilation,shorten the time of mechanical ventilation,and decrease the complications of burn.

ObjectiveTo explore the effect of mentality-controlling on local microcirculation of acupuncture at Hegu （LI 4）. MethodsForty healthy subjects were randomly divided into simple acupuncture group and mentality-controlling acupuncture group， with 20 cases in each group. The simple acupuncture group was acupunctured at Hegu （LI 4） on the right hand of the patient. In mentality-controlling acupuncture group， an audio clip was played to guide the participants to control their mentality when needle retention for 5 min after performing acupuncture twirling mani-pulation. The microcirculatory blood perfusion units （MBPU） was captured and compared between groups of participants using laser speckle contrast imaging （LSCI） for 5 mins in each of the four stages， state before acupuncture （R1）， after needle insertion （A1）， after needle twirling （A2） and after needle withdrawal （R2）. The participants' feelings such as relaxation， concentration， drowsiness， energy flow at acupoints were compared between groups， and the adverse reactions were recorded. ResultsThe MBPU values of R1， A1， A2 and R2 stages in mentality-controlling acupuncture group were 67.92±18.40 PU， 168.13±46.03 PU， 144.19±44.40 PU， 159.73±65.21 PU， respectively. The simple acupuncture group were 79.85 （66.80， 99.40）PU， 193.31 （173.15， 224.80）PU， 147.68 （128.12， 198.30）PU， 158.09 （126.05， 207.59）PU respectively. There was a statistically significant difference in MBPU between groups of the four stages （P＜0.01）. Among them， the MBPU in the A1 stage of both groups was significantly larger than that in the R1 stage， the MBPU in the A2 stage significantly smaller than that in the A1 stage， and the MBPU in the R2 stage was significantly larger than that in the R1 stage （P＜0.01）. MBPU in the R2 stage of the mentality-controlling acupuncture group was larger than that in the A2 stage （P＜0.05）. The difference of MBPU between A2 and A1 in mentality-controlling acupuncture group was significantly smaller than that in the simple acupuncture group， and the difference was statistically significant （t = 3.79， P＜0.01）. In mentality-controlling acupuncture group， 18 participants felt relaxed （90%）， 15 concentrated （75%）， 3 felt sleepy （15%）， and 14 felt energy flow at acupoints （70%）； while in the simple acupuncture group， 13 participants felt relaxed and sleepy （65%）， 6 concentrated and 6 felt energy flow at acupoints （30%）. The number of participants with concentration and energy flow at acupoints in mentality-controlling acupuncture group was higher than that in the simple acupuncture group， and the number felt sleepy was lower than that in the simple acupuncture group （P＜0.05）. No needle fainting， needle site infection， local haematoma and any other adverse reactions were found in both groups. ConclusionAcupuncture could affect the changes of local microcirculation， and controlling mentality during acupuncture can slow the rate of MBPU reduction and enhance the post-acupuncture effect with a favourable safety profile.