Objective In order to study the effects of three drainage methods after operation of breast cancer. Methods We demonstrated the drainage reliability of the negative pressure bottles by measuring their negative pressures.We reviewed the incidence of flap dropsy of 103 patients with breast cancer operated from 1988 to 2001.Results Negative pressure of the bottle made by ourselves is 83.33 kPa at the room temperature and 74.12 kPa after 200ml fluid being drained. The incidence of skin flap dropsy of the negative pressure bottle is significantly lower than those in another two groups.Conclusion The negative pressure bottle is reliable, convenient and applicable in all levels of hospital.

0 05 by ? 2 test). The rats in intravenous groups (10 6,10 7) and in intratumoral group had significant prolonged survival (compared with control group, P