The trace elements of Halibios were analysed and the effects of 5 kinds of Halibios on antiirritability, radical scavenging, memeory MAO-B activity, hemorheologic changes in animal were studied. The results showed that Halibios Acaudina molpadioides, Hippocampus Kuda ,Cavernularia habereri,Octopus valgaris ,and Octopus ocellatus contain abundant trace elements,most of them have effects on antiirritability, radical scavenging, rising memory and depressing MAO-B activity in animmal.