Objective To evaluate the effectiveness of anus misoprostol for cervial dilation for menopausal women in hysteroscopy.Methods 86 menopausal women before hysteroscopy were divided into two groups.The misoprostol group(46 cases) were handled with misoprostal through anus.The control group(40 cases) were injected with lidocaine through cervix.Results Compared with the control group,the effective cervial dilatation rate of misoprostol groupwas significantly higher,and the incidence of abortion syndrome was lower.Conclusion Anus misoprostol can significantly facilitate cervial dilation in menopausal women before hysteroscopy.