5.Ideas on Chinese traditional osteopathy, biomechanics mechanism of manipulation and mathematics-physics expressions
Zhao Na Mu La ; Gen-quan LI ; He-ping SU ; Chang-ming BAO ; Ji Ri Ga La ; Chao-lu WANG
Chinese Journal of Tissue Engineering Research 2005;9(14):244-247
BACKGROUND: Chinese traditional osteopathy is long in history, unique in manipulation and miraculous in therapeutic effect. But people understand it more m perception rather than in theory, more in application rather than in development. There is little research truly on the bioseience.OBJECTIVE: To probe into the macro-idea of Chinese traditional osteopathy, micro-mechanisms on characters and mathematics-physics models, aiming to provide new principles and approaches of treatment for the daily increased bone trauma, fracture and sport injury.SETTING: Physics and machine-electron college of a university, and its affiliated hospital.METHODS: Based on the natural concept of "integration between heaven and human being" and new concept of holistic medicine in Chinese traditional osteopathy, the macro-idea and characters of reduction and union of fracture are generalized from the characters of natural therapy and the biomechanical mechanisms and characters of reduction and union of fracture are summarized from the micro-reaction of bone repair and union so as to discover biomechanical mechanisms and characters of reduction and union of fracture and further to set up biomechanical models and mathematics-physics expressions during the treatment.RESULTS: Chinese traditional osteopathy envelopes macro-idea of "initiative reduction-functional union" in fracture and micro-mechanism on "stress adaptability-functional adaptability" of bone repair and union.CONCLUSION: Chinese traditional osteopathy compiles with the natural,green and non-traumatic therapy in bio-natural law of bone repair and union and supports the theme of "high thought and high skill".
6.Weekly Cyclophosphamide Pulse Therapy Combined with Corticosteroids in the Treatment of Pemphigus
Guo-Quan JIA ; Zhi-Qiang CHEN ; He-Lian LI ; Pan-Gen CUI ; Wen-Yan XU
Acta Academiae Medicinae Sinicae 2001;23(2):173-175
Objective To investigate the better regimen of combined cyclophosphamide pulse therapy with corticosteroids in the treatment of Pemphigus. Methods Intravenous cyclophosphamide was given weekly in a dosage of 600 mg to those Pemphigus patients whose conditions couldn't be improved by corticosteroids (oral prednisone 1.2~1.5 mg/kg/d) alone. Results Ten patients with Pemphigus received weekly cyclophosphomide therapy in addition to corticosteroid. Patients conditions improved quickly, without side effects. Conclusions Cyclophosphamide weekly pulse therapy combined with corticosteroids is a good regimen in the treatment of Pemphigus.
7.Analysis on genetic stability in different development stages of Dendrobium huoshanense by RAPD.
Shi-Quan LIU ; Xiao-Jun LI ; Qing-Bo YU ; Hong XIE ; Gen-Yu ZHOU
China Journal of Chinese Materia Medica 2007;32(10):902-905
OBJECTIVETo research the hereditary stability of Dendrobium huoshanense which were subcultured 7-8 times in the same tissue culture system.
METHODUsing three primers of arbitrary decamer oligonucleotide sequences from 20 primers for DNA amplification, random amplified polymorphic DNA (RAPD) were performed.
RESULTThe genetic similarity coefficient was varied from 85.4% to 98.4%. The variation of protocorm, germination and monoleaf were rather more notable than that of bileaf and inflorescence.
CONCLUSIONThe variation of the same pod is quite small. It is feasible to set up the rapid propagation system of D. huoshanense
Analysis of Variance ; DNA Primers ; DNA, Plant ; analysis ; genetics ; Dendrobium ; genetics ; growth & development ; Genetic Variation ; Germination ; genetics ; Plants, Medicinal ; genetics ; growth & development ; Random Amplified Polymorphic DNA Technique ; Time Factors ; Tissue Culture Techniques
8.Clinical effect of erythromycin and azithromycin in the treatment of pediatric mycoplasma pneumonia
Jia-Hui CHEN ; Gen-Quan YIN ; Jia-Lu YU ; Li DENG
The Chinese Journal of Clinical Pharmacology 2015;(8):587-589
Objective To evaluate the clinical efficacy of erythromycin and azithromycin sequential therapy with single azithromycin treatment on pediatric mycoplasma pneumonia .Methods One hundred and fourteen cases of pediatric mycoplasma pneumonia were randomly divided into two groups, with 57 cases in each group.Patients in the treatment group were treated with erythromycin combined with azithromycin , and those in the control group were treated with azithromycin , and the treatment lasted for 3 weeks.The data of clinical efficacy , clinical symptoms and hospitaliza-tion time of two groups were compared after treatment . Results The total effective rate of the treatment group was 96.49%, significantly higher than that of control group ( 77.19%) ( P<0.01 ) . The time points that fever , cough and lung rales disappeared and hospi-talization time of the treatment group were significantly lower than those of control group ( P<0.01 ).The rate of adverse reactions in the treatment group was 7.02% and 3.51% in control group but without statistical difference ( P>0.05).Conclusion Erythromycin combined with azithro-mycin treatment for pediatric mycoplasma pneumonia is notably effective .
9.Necessity of No.13 lymph node dissection in advanced gastric carcinoma.
Gen PENG ; Zhi-gang JIE ; Zheng-rong LI ; Yi LIU ; Xiao-ping XIE ; Sheng-quan CHEN ; Wei LI ; Yi CAO
Chinese Journal of Gastrointestinal Surgery 2012;15(2):145-148
OBJECTIVETo investigate the feasibility and necessity of No.13 lymph node dissection for advanced gastric carcinoma.
METHODSClinical data of 144 cases who were diagnosed as TNMII-III stage gastric carcinoma were collected from January 2007 to December 2009 in the Department of General Surgery at the First Affiliated Hospital of Nanchang University. Seventy-two cases who received D2 radical gastrectomy plus No.13 lymph node dissection were selected as the study group, and they were matched 1:1 to 72 cases who received D2 Radical gastrectomy (the control group) for TNMII-III stage gastric carcinoma. The differences in the intraoperative and postoperative parameters and survival time were compared, and the factors associated with No.13 lymph node metastasis were analyzed.
RESULTSThere were no significant differences between the two groups in operative time [(2.8 ± 0.4) h vs. (2.7 ± 0.4) h], blood loss [(191.9 ± 81.5) ml vs. (186.0 ± 81.7) ml], the incidence of postoperative complications (18.1% vs. 15.3%), length of hospital stay [(12.3 ± 4.2) d vs. (11.9 ± 3.2) d] and 3-year survival rate (63% vs. 57%) (all P>0.05). In the study group, there were 15 patients (20.8%) with positive No.13 lymph nodes, and the 3-year survival rate was 13%, significantly lower compared to those with negative No.13 lymph node (73%, n=57) (P<0.05). Multivariate analysis showed that N stage (P<0.01) and histological type (P<0.05) were independently associated with No.13 lymph node metastasis.
CONCLUSIONNo.13 lymph node dissection for TNMII-III stage gastric cancer is feasible and necessary.
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Lymph Node Excision ; methods ; Lymphatic Metastasis ; Male ; Middle Aged ; Stomach Neoplasms ; surgery
10.The preliminary study of metallic stent implantation in combination with three-dimensional conformal radiation therapy in the treatment of hepatocellular carcinoma patients with portal vein tumor thrombus.
Cheng-gang WANG ; Xiao-lin WANG ; Gao-quan GONG ; Gang CHEN ; Zhao-chong ZENG ; Wei-li QIU ; Gen-lai LIN ; Yi CHEN ; Guo-ping LI
Chinese Journal of Hepatology 2009;17(6):417-421
OBJECTIVETo study the clinical efficiency of metallic stent implantation in combination with three-dimensional conformal radiation therapy in the treatment of hepatocellular carcinoma (HCC) patients with portal vein tumor thrombus.
METHODS22 cases of HCC patients with portal vein tumor thrombus were devided into 2 groups: 10 patients (group A) recieved stent implantation in combination with conformal radiation therapy, 12 patients (group B) recieved stent implantation and transcatheter arterial chemoembolization. The adverse reactions, and liver function before and after treatment were compared between the two groups. The stent patency rate at 4, 6 and 12 months and the survival rate at 3, 6 and 12 months were followed up. Comparison of liver function was analyzed by Wilcoxon signed rank test. Comparison of stent patency rate curves and survival curves was analyzed by Log rank test.
RESULTSThe portal vein catheterization was successful in all the patients. The stents were successfully implanted by transhepatic portal vein approach, and portal vein stenosis was re-opened. There was no abdominal hemorrhage in all the patients, but there were symptoms of abdominalgia, fever, nausea, vomiting and flatulence of varying degrees after interventional operation, and these symptoms were relieved by symptomatic treatment in one week. All patients in group A completed the treatment. I-II degree gastrointestinal tract reactions occurred in 3 cases, I-II degree myelosuppression occurred in 2 cases, and they were all completely relieved after treatment. The stent patency rate at 4, 6 and 12 months was 90%, 70%, 30% in group A; and 50%, 25% , 16.7% in group B (P < 0.05). The survival rate at 3, 6 and 12 months was 100%, 80% , 30% in group A and 91.7%, 41.7%, 16.7% in group B (P < 0.05).
CONCLUSIONStent implantation combined with three-dimensional conformal radiation therapy is a good treatment for hepatocellular carcinoma with portal vein tumor thrombus and causes less damage to liver.
Adult ; Aged ; Carcinoma, Hepatocellular ; complications ; diagnostic imaging ; therapy ; Combined Modality Therapy ; Female ; Follow-Up Studies ; Humans ; Liver Neoplasms ; complications ; diagnostic imaging ; therapy ; Male ; Metals ; Middle Aged ; Neoplasm Invasiveness ; Portal Vein ; pathology ; Radiography ; Radiotherapy, Conformal ; Radiotherapy, Intensity-Modulated ; Retrospective Studies ; Stents ; Survival Rate ; Treatment Outcome ; Venous Thrombosis ; diagnostic imaging ; etiology ; therapy