1.Contrast Media-Related Complications and Their Management in Cerebrovascular Intervention
Gelin XU ; Wusheng ZHU ; Xinfeng LIU
International Journal of Cerebrovascular Diseases 2006;0(09):-
Endovascular intervention is an effective method in the treatment of cerebrovascular stenosis. With the advancement of techniques and improvement of equipment, the application area of this treatment is expanding and the number of patients treated is increasing. Accordingly, the use of contrast media is improving continuously in endovascular intervention. An increasing number of contrast media-related complications have also been reported. This paper briefly reviews the contrast media-related complications and their management in endovascular intervention.
2.Interventional Endovascular Treatment of Intracranial Stenosis
Xinying FAN ; Gelin XU ; Xinfeng LIU
International Journal of Cerebrovascular Diseases 2006;0(09):-
Intracranial stentosis is one of the important causes of ischemic stroke. In recently years, with the continuously development of endovascular intervention, angioplasty and stenting have become effective treatment options for intracranial stenosis. However, the indications, technical points, complications and prognosis of this treatment remain to be investigated and explored.
3.Endovascular Intervention of Vertebrobasilar Artery Stenosis
Yuping MA ; Gelin XU ; Xinfeng LIU
International Journal of Cerebrovascular Diseases 2006;0(09):-
Approximately one-quarter of ischemic stroke occurred in vertebrobasilar artery system. Atherosclerotic vertebrobasilar artery stenosis is one of the major causes of posterior circulation stroke. In addition to the conventional medical and surgical treatment, endovascular intervention has received more and more attention, and it has become the most promising therapeutic approach.
4.Progress in Research on Endovascular Treatment of Carotid Stenosis
Xinfeng LIU ; Gelin XU ; Minmin MA
International Journal of Cerebrovascular Diseases 2006;0(09):-
Endovascular treatment is becoming a novel technique in the treatment of carotid stenosis. Since this technique is in its infancy, there are many controversies on this technique and theory now. This paper briefly reviews the most recent advances in endovascular treatment of carotid stenosis.
5.Advances in the Treatment of Cerebral Venous Thrombosis
Wusheng ZHU ; Gelin XU ; Xinfeng LIU
International Journal of Cerebrovascular Diseases 2006;0(09):-
Cerebral venous thrombosis is a rare cerebral venous occlusive disease. Its clinical manifestations are variable, and this may lead to misdiagnosis or mistreatment. Prompt treatment is essential to improve its prognosis. This article reviews the recent treatment methods, especially the interventional endovascular treatment.
6.The Study Category and Method of Cerebrovascular Intervention
Wenxin ZHAO ; Gelin XU ; Xinfeng LIU
International Journal of Cerebrovascular Diseases 2006;0(09):-
Cerebrovascular Intervention is to study the subject of diagnosing and treating cerebrovascular disease with interventional endovascular techniques monitored and guided by neuroimaging. With the continuous development of computer, imaging and angiography techniques, their study method and category are being innovated and expanded continuously in recent years. This article reviews the novel techniques of imaging diagnosis, intra-arterial thrombolysis, angioplasty and endovascular embolization in cerebrovascular diseases, and also evaluates their clinical applications.
7.A study of relationship between Oxfordshire Community Stroke Project classification and middle cerebral arterial lesions among patients with acute ischemic stroke.
Huajun ZHANG ; Wusheng ZHU ; Gelin XU
Chinese Journal of Practical Internal Medicine 2006;0(24):-
Objective To study the relationship between Oxfordshire Community Stroke Project(OCSP)classification and middle cerebral artery(MCA)lesions detected by digital subtraction angiography among patients with acute MCA territorial infarction.Methods One hundred and fifty-four patients with acute MCA territorial infarction,who were obtained from Jinling Hospital during May 2002 to December 2005,were classified into total anterior circulation infarction(TACI),partial anterior circulation infarction(PACI)and lacunar infarction(LACI).Results Compared with LACI subtype,prevalence of MCA main stem occlusion in patients with TACI subtype was higher(P
8.Ivy sign of moyamoya disease
Xianjun HUANG ; Zhiming ZHOU ; Gelin XU
International Journal of Cerebrovascular Diseases 2016;24(2):131-133
Moyamoya disease is an uncommon cerebral disease, but its morbidity is relatively high in East Asian populations. Ivy sign refers to the dot or linear high signal phenomenon in MRI T1 enhanced sequence in patients with moyamoya disease. It mainly distributes in the pial surface of cerebral cortex or within subarachnoid space. It has important significance for diagnosing moyamoya disease and assessing the staging and prognosis of moyamoya disease. This article briefly reviews this imaging finding and its significance.
9.Advances in the genetics of moyamoya disease
Xiaomeng WANG ; Xianjun HUANG ; Gelin XU
International Journal of Cerebrovascular Diseases 2012;20(7):508-512
Moyamoya disease is a rare cerebrovascular disease.Its incidence is higher in the East Asia.The pathogenesis of MMD remains unclear at present,but the epidemiological research both at home and abroad suggests that the genetic factors play an important role in the onset of MMD.This article briefly reviews the recent progress in research on MMD related genes.
10.Clopidogrel resistance and genetic polymorphism
Wenshan SUN ; Yongkun LI ; Gelin XU
International Journal of Cerebrovascular Diseases 2011;19(11):841-844
Clopidogrel is an antiplatelet drug widely used in clinical practice now.It has been used as the secondary prevention medication for myocardial infarction,ischemic stroke,and peripheral vascular disease.However,the anti-platelet aggregation effect of clopidogrel has significant individual differences.A large part of patients have clopidogrel resistance phenomenon.The mechanism of clopidogrel resistance is not fully understood.The genetic polymorphism is an important cause of clopidogrel resistance,including ABCB1,CYP2C19,CYP3A4,CYP3A5,P2Y12,and ITGB3.