1.EFFECTS OF GINSENOSIDES AND PANTOCRINE ON THE FUNCTION OF REPRODUCTIVE ENDOCRINE SYSTEM IN MALE RATS
Chinese Pharmacological Bulletin 1986;0(04):-
In vitro experiment, results showed the that the LH secretion of adenohypophysis incubated with Ginsenosides ( G ) and Pantoc-rine ( P ) was significantly increased, similar to the exciting effect of LRH which stimulats LH secretion. By addition of G or P and Indomethacin (an inhibitor of PGs synthesis) at the same time, however, the LH secretion was significantly decreased. It appears that PGs may be involved in the regulation of the exciting effect of G and P on LH secretion. The experiment in vivo also demonstrated that in healthy young male rats injected with P by S.c.,thetestosterone content in plasma had significant increase, that the binding capacity of testicular tissue to 125I-HCG (receptor function) did not change clearly.
4.A New Method for the Extraction of Tea-Polyphenols
Chinese Traditional and Herbal Drugs 1994;0(03):-
A new method for the extraction of tea-polypbenols (TP ) from tea using AlCl3 as precipitating agents was proposed. Compared with tbe traditional extraction method using organic solvents, it is shown that the new method is simple and can be operated easily. The extraction rate of TP by the new method could reach 10.5% and the content of the effective ingredients of TP could reach over 99.5%
6.Effect of preoperative neoadjuvant chemotherapy on cervical carcinoma
Chinese Journal of Primary Medicine and Pharmacy 2010;17(23):3175-3177
Objective To study the value of neoadjuvant chemotherapy in the treatment of cervical carcinoma. MethodsA clinical prospective study was carried out from Jan.1997 to Dec.2003,118 patients with cervical carcinoma were given two cycles of combined chemotherapy before operation(neoadjuvant chemotherapy group,group A).102 patients accepted surgery alone in our hospital from Jan.1997 to Dec.2003 were chosen as the comparison group(group B).Survival rate and complications were observed and analysed. Results5 year survival rate in group A was significantly higher than that in group B(P<0.01),The 5 year survival rate was significantly higher in group A than in group B,despite of different pathological types,with or without radiochemotherapy(P<0.05).The recurrent rate was lower in group A than that in group B,which show significant difference in the 5 year recurrent rate(P<0.05). ConclusionNeoadjuvant chemotherapy is an effective method for the treatment of cervical carcinoma in early stage.Because of satisfactory short-term control rate,excision rate,long-term survival rate and low recurrent and metastatic rate,neoadjuvant chemotherapy is worth popularizing in clinical treatment.
7.Hip stress technical strength training and evaluation:Document comparison and logical analysis
Qi GE ; Tao HONG ; Bingcheng WANG
Chinese Journal of Tissue Engineering Research 2013;(46):8083-8089
BACKGROUND:At the beginning of the 20th century a strength training method in the backward direction appeared:hip stress strength training method. There are many articles focusing on the concept, function, effect and mechanism of this training method. So far, relevant research has formed a unique branch of special strength training research directions.
OBJECTIVE:To conclude the concept, function, effect, features and mechanisms of hip stress technical strength training through the systematic analysis of literature concerning hip stress strength training. METHODS:CNKI (1998/2010) and Wanfang databases were searched by the first author for relevant articles. The keywords were“hip stress, strength training, trajectory control, exercise training, muscle strength, knee, physical fitness, bone”in Chinese and English. The obtained data were summarized using contrast method and logic analysis method.
RESULTS AND CONCLUSION:Total y 90 papers were retrieved, and final y 34 papers were included. The results showed that the hip technical strength training method is the most effective training method currently to cultivate the running, jumping and throwing back pedaling force after hip extension forces. It has a new training idea and special training equipments, which can effectively solve many sports difficulties in strength training and technical training and has the vital significance for the high-level sports training, skil s assessment and sports teaching. Hip stress special technical strength training research has formed a special research branch of special strength trainings, which wil play a more significant research role.
8.Clinical Observation on Comprehensive Treatment of 80 Cases of Chronic Type Ⅲ Prostatitis by Elongated Needle, Microwave and Moritatherapy
Hui LI ; Hong ZHANG ; Jianqiang GE
Journal of Acupuncture and Tuina Science 2005;3(6):8-10
After 160 cases of chronic type Ⅲ prostatitis were divided into the treatment group (n= 80) and control group (n = 80), in the treatment group, first Zhibian (BL 54) was punctured toward Shuidao (ST 28) and then Qihai (CV 6), Guanyuan (CV 4), Shuidao (ST 28)Baihui (GV 20), Fengchi (GB 20), Sishencong (Ex-HN 1), Sanyinjiao (SP 6) and Taichong (LR 3) were punctured, and at the same time, digital computerized microwave apparatus was inserted into the anus for microwave treatment. Afterward, moritatherapy was applied for psychological consultation for the patients. In the control group, compound sinomin and Phenoxybenzamine Hydrochloride Tablets were used orally. The results showed that the therapeutic effects were respectively 92.5% and 68.8% in two groups, with statistic significance (P < 0.01).
9.Mechanism of anti-proliferation effect of ginseng Rh_2(G-Rh_2) on mouse MFC gastric cells
Ge WU ; Hong LI ; Shijie YANG
Chinese Pharmacological Bulletin 1987;0(01):-
Aim To investigate the molecular mechanism of anti-proliferation effect of Ginsenoside Rh2(G-Rh2)on mouse MFC gastric cells.Methods The cell viability was determined by MTT method and the state of cell proliferation was analyzed.The morphologic changes were observed by invert microscope and fluorescence microscope(Hoechst 33258).Early apoptotic rate was detected by Annexin Ⅴ-FITC through flow cytometry.Western blot was used to detect the p-JNK and p-c-jun activity in MFC cells.Immunocytochemistry staining was used to detect caspase-3 positive cells.Results G-Rh2 could inhibit proliferation of MFC cells in a dose-and-time-dependent manner.The morphological changes of apoptosis were observed in MFC cells after G-Rh2 treatment.The apoptotic ratio was increased.The phosphorylation of c-Jun and c-Jun NH2-terminal kinase(JNK)activity increased with time within 4 h compared with that of control.The expression of caspase-3 positive cells was increased.But all the above could be partly inhibited by pre-treatment with SP600125(5 ?mol?L-1)for 2 h.Conclusion G-Rh2 can decrease cell viability by inducing apoptosis and the process may be associated with the activation of JNK transduction pathway and expression of caspase-3.
10.Analysis and classification of functional dyspepsia
Hong TIAN ; Hanjian ZHOU ; Lan GE
Clinical Medicine of China 2000;0(11):-
Objective To investigate the proportions of the functional dyspepsia (FD) subgroups and to explore theri relationship with Helicobacter pylori (HP).Methods 186 cases with FD received questionaires about their condition and were typed according to their symptom.HP was detected through urease test,spear technique and cultivation.Results The proportion and HP-positive rate of the subgroup were 11.29%,14.24% in reflux-type dyspepsia,13.98%,46.15% in ulcer-type dyspepsin,48.39%,41.11% in dysmotility-type dyspepsia and 26.34%, 38.78% in complex dyspepsia,respectively.The total HP-positive rate of FD is 38.17%.Conclusion Dysmotility-type dyspepsia is most common.Some subgroups are overlapping with each other.There is no relationship between FD and HP.The HP-positive rate of the reflux-type dyspepsia is lower.This observation suggests that HP may have protective effects on esophagus.