Objective To observe the clinical efficacy of percutaneous minimally invasive plate osteosynthesis(MIPPO) in treatment of senile proximal humeral fractures(SPHF).Methods The clinical data of 41 SPHF patients treated by MIPPO were analyzed retrospectively.The effect of surgery was evaluated by Neer scoring system.Results 41 patients were follow-up for 5 to 19 months (mean 11.6 months).Based on the Neer scoring criteria:the turn of excellent,good,fair or poor were 25 cases,12 cases,3 cases,1 case,the excellent rate was 90.2％.Never happened avascular necrosis of the humeral head,plate and screw fracture,nerve injury,fractures unhealed or delay healing and other negative phenomena.Conclusion The application of MIPPO in treatment of SPHF is easy to operate,little nerve damage,good fixed performance,high reliability,which is worthy of clinical application.

The anti-thyrotropin antibody (TSHab) in 29 normal subjects and 58 patients with Graves' disease (GD) with 125I-TSH as tracer. The TSHab indices were 0.85?0.22 in normal subjects, 1.47?0.35 (P0.05) in GD treated by antithyroid drugs. The result of staphylococus aureus Cowan I precipitation test showed that the antibodies binding to TSH belong to IgG. The existance of TSHab in GD suggested that the reaction of idiotype/anti-Jdiotype was involved in autoimmune mechanism of GD.

Enhancers are cis-acting elements of DNA which can enhance the transcription activity of promotors.Emerge of Bioinformatics brings great convenience for enhancers investigation.The utilization of tumor-specific promotors modified by enhancers to make the expression of theoretical gene or effector in specified organisms or cells,and to implement targeted therapy of tumor,is a significant and potential gene therapy method.

In order to study the influencing factors of clinical teaching quality,students studying in non-affiliated hospitals,clinical teachers,teaching management personnel in hospitals and university were investigated as study subjects with Delphi Method.Suggestions were put forward that non-affiliated hospitals should improve the construction of the teaching staff,emphasize the teaching management,and strengthen students' education and management for improving clinical teaching quality in non-affiliated hospitals.

Objective To evaluate the clinical effects of ray protective agent which prevented radiation dermatitis in head carcinoma patients.Methods 112 patients which prevented radiation dermatitis in head carcinoma patients were divided into the two groups by the single-blind random method.The treated group of 60 patients received the spray of ray protective agent on the radiated skin area 30 min prior and after the radiation exposure with health education,and the control group of 52 patients without any treatment for protection,except health education.The radiation-induced skin damage was observed and the incidence of skin damage was assessed.Results The incidence of 2 and 3 degree skin reaction of the treated group were 15 cases(25.0％) and 4 cases(6.7％),and the incidence of 2 and 3 degree skin reaction of the control group were 21 cases(40.4％) and 28 cases(53.8％),the difference between the two groups had statistical significance(x2 =48.902,24.113,all P ＜ 0.05).Conclusion Ray protective agent is an effective way in reducing the degree of radiation dermatitis,which can relieve pain and improve the quality of life.

The significance of strengthening the construction of teaching staff in non-affiliated hospitals was discussed. Combined with the problems in strengthening the construction of teaching staff, some countermeasures were put forward, such as emphasizing on teaching, enhancing teaching awareness, improving teaching institutions and teaching rules, selecting teaching staff with high standards, strengthening teacher's teaching ability, establishing teaching quality guarantee system and teaching stimulating mechanism.

TraumaistheNo .1causeofdeathinpersonsundertheageof 4 5andtheNo .3causeof alldeaths .Manytraumapatientsdieofmultipleorganfailure(MOF) ,inducedbysystemicinflammatoryre sponsesyndrome(SIRS) .Thispaperreviewstherelationsoftraumaticshockwithsystemicinflammation . [

Objective:To compare the caries removal efficiency of Carisolv with that of drilling in deciduous teeth.Methods:Thirty-two children,aged from 6 to 9 years,with symmetric coronal medium or deep caries in deciduous teeth,were involved in the clinical study.According to a split-mouth design,in each patient,caries tissue was removed by using a round bur on one side,and Carisolv on the other side.After caries removal,the teeth were restored with composite resin.Patients were asked to fill in a postoperative questionnaire,including patient acceptance of technique preference.6 months after operation the restorations were checked.Results:The time(min) for Carisolv caries removal and for drilling method were 4.33?1.25 and 2.58?0.82 respectively(P0.05).Conclusion:Carisolv is a time-consuming technique,but the majority of patients accepte Carisolv because of less pain.Carisolv may have no effect on the incidence of marginal microleakage and secondary caries.

Objective] To summarize the clinical experience to treat threatened abortion with Zhejiang Chen Mushan Gynecology calming fetus. [Method] By analyzing the understanding of Chen’s Gynecology to etiology and pathogenesis of threaten abortion, to review typical cases and summarize its characteristic of treatment, to sum up the clinical experience of threatened abortion. [Result]The etiology of threaten abortion of Chen ’s Gynecology is due to fetus fire flaring up, qi and blood deficiency, spleen and kidney insufficiency, therefor causing fetus yuan qi not solid, fetus unease and/or threatened abortion. The paper introduces Chen’s miscarriage prevention and proposes to treat threatened abortion by focusing on tonifying qi and blood, strengthening kidney and spleen, clearing heat and cooling blood, integrating prevention with treatment, emphasizing in harmonizing in the treatment. [Conclusion] Chen’s treating method for threatened abortion by calming fetus has accumulated rich clinical experiences with strong characteristics, it is worth to inheritance and popularizing.

Objective To explore the regularities in clinical application of acupoints in acupuncture treatment for ovulatory disorder infertility and provide guidance for clinical treatment of this disease.Methods China National Knowledge Infrastructure, Wanfang Database, VIP Chinese Scientific Journal Database and China Biomedical Literature Database were searched to retrieve clinical literature on acupuncture treatment for ovulatory disorder infertility published from 1996 to 2015 and analyze the application frequency of main acupoints statistically, acupoint meridian tropism and regions, and regularities in acupoint selection.Results A total of 98 articles were included, involvng 58 main acupoints, 608 frequencies of using main acupoints and 11 meridians to which the main acupoints were related. The four most frequently used acupoints were Guanyuan, Sanyinjiao, Zigong and Zhongji. The meridians of which the main acupoints were used at the first five highest frequencies were in order the Ren meridian, the spleen meridian, the stomach meridian, the bladder meridian and the kidney meridian.Conclusions Guanyuan, Sanyinjiao, Zigong and Zhongji are the most frequently used acupoints in modern acupuncture treatment for ovulatory disorder infertility. The principles of acupoint selection are based on visceral and meridional syndrome differentiations. Acupoint selection along the meridian and local acupoint selection are the main methods and acupoint selection according the experience is an auxiliary method.