1.The development of the research in the bodysurf ace mapping area
International Journal of Biomedical Engineering 2001;24(2):64-70
Body surface mapping is introduced in this paper. The research of bodysurface mapping involves two main aspects :data acquiring system and data processing methods. The recommended design applies the virtual instruments concept and high speed open bus standard. The data processing methods involve qualitative and quantitative methods. Dynamic and static mapping techniques are introduced as the qualitative methods. Statistical methods,inverse calculation and principle component analysis are introduced as the quantitative methods.
2.The Differences of CT Appearance in Single Vertebral Tuberculosis and Metastasis
Journal of Practical Radiology 2001;0(06):-
Objective To investigate the morphological difference of spinal single vertebral tuberculosis and metastasis by means of CT.Methods CT features of 16 cases of single vertebral tuberculosis and 17 cases of single vertebral metastasis which were proven by clinically and/or pathology, were retrospectively analyzed,and then the CT differential criteria of the two categories of diseases was recommended.Results The reliable CT findings for vertebral tuberculosis were as follows: involvement of anteriomedial potion of vatebral body,presence of sequstra in lesion ,marginal sclerosis in the edge of lesion,calcification within paravertebralmass or abscesses ,only edge enhancement of more of paravertebralmass.Metastasis was characterized by involvement of posteriomedial portion of vertebral bone,absence of sequestra within lesion ,no calcification within paravertebralmass.Both of them had normal intervertebral disc.Conclusion The different CT features of the single vertebral tuberculosis and metastasis are helpful in differerntiating diagnosis ,the morphological change of intervertebral discs is not helpful in differerntiating diagnosis .
3.THE STUDY OF PATHOGENIC BACTERIA AND WHOLE CELL VACCINE ON SPARUS LATUS VIBRIO DISEASE
Microbiology 1992;0(02):-
Physiological and biochemical characteristics,drug sensitivity of pathogenic bacteria isolated from the diseased Sparus latus in Zhanjiang,Guangdong,and inactivated whole cell vaccine were studied.The results show that the isolated strain is Vibrio alginolyticus and is highly sensitive to tetracycline,gentamycin,chloramphenicol,and so on.But it is not sensitive to erythromycin and penicillin K.It also shows that the pathogen is inactivated more easily at pH6.0 than at pH8.4 when formalin is used.The whole cell vaccine can strengthen Sparus latus's immuno function and lessen their death rate when fish are infected by the Vibrio alginolyticus.
5.Variation of the human leptin receptor gene in obese Chinese population
Gang CHEN ; Min LUO ; Wei DING
Chinese Journal of Endocrinology and Metabolism 2001;0(05):-
Objective To investigate the relationship between the genetic variation of leptin receptor and obesity in Chinese population. Methods Genomic DNA was extracted from 50 obese subjects 〔Body mass index (BMI)≥30 kg/m 2〕 and 50 normal individuals (BMI
6.Interferon gamma enhances the cytotoxicity of 5′-deoxy-5-fluorouridine and 5-fluorouracil against human bladder cancer cells
Gang LI ; Yuanfang ZHANG ; Qiang DING
Chinese Journal of Urology 2001;0(07):-
Objective To investigate the regulative effect of interferon gamma (INF?) on the expression of platelet-derived endothelial cell growth factor / thymidine phosphorylase (PD-ECGF/TP) and its relation with the anti-cancer effect of 5′-deoxy-5-fluorouridine (5'DFUR) and 5-fluorouracil (5FU) in T24 bladder cancer cells. Methods PD-ECGF/TP mRNA and protein expressions were determined by RT-PCR and Western blot,respectively.Cytotoxicity of 5′DFUR,5FU or mitomycin C (MMC) against T24 cells was evaluated by MTS assay. Results The expressions of PD-ECGF/TP mRNA and protein were concomitantly elevated in T24 cells after INF? treatment.And INF? decreased IC 50 s of 5′DFUR [from (16.0? 3.6 )mmol/L to (6.2?0.9)mmol/L,( P
7.Comparison of tooth profile in Chinese, Caucasian and Japanese with normal occlusion
Jia GANG ; Ding YIN ; Wang FENG
Journal of Practical Stomatology 2000;0(05):-
Objective: To study the difference in tooth profile among Chinese,Caucasian and Japanese with normal occlusion.Methods: The data of the measurments of Chinese,Caucasian and Japanese with normal occlusion were collected from published studies.Crown angulation,crown inclination and crown convex were used in the comparation among the peoples. Results: Tooth profile in Chinese was significantly different from that of Caucasian but was similar to that of Japanese. Conclusion: The orthodontic appliances should be modified when we use the straight wire appliances that is suitable for Caucasian and Japanese.
8.EFFECTS OF ANGⅡ/IFN-? ON EXPRESSION OF TGF-?R TYPE I OF RAT VSMC
Gang DING ; Zhiming ZHU ; Zuoq ZHANG
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
Transforming growth factor ?1 (TGF ?1) promotes the formation of extracellular medium(ECM).This study was designed to investigate the effects of angiotensinⅡ(AngⅡ) and Interferon ?(IFN ?) on expression of TGF ? Receptor type I(T?R I) in rat vascular smooth muscle cell(VSMC). We observed the changes of T?R I expression after 24h stimulation with AngⅡ(10 -7 M) and IFN ?(500U/ml) by Western blotting, and found that AngⅡ markedly stimulated expression of T?R I from 62 24?4 39 in control group to 103 06?9 34 in AngⅡ group (expressed in OD, P
9.Lack effect of metabotropic glutamate receptors on neurotoxicit y of PC12 cells induced by 6-OHDA
Changhong MENG ; Jianhua DING ; Gang HU
Chinese Journal of Clinical Pharmacology and Therapeutics 2000;0(03):-
AIM: To explore if metabotropic glutamate receptors (mGluRs) i nduces neuroprotection against 6-hydroxydopamine (6-OHDA) neurotoxicity in PC1 2 cells. METHODS: The alteration of the glutamate in extracellul ar fluid of PC12 cells was detected by high performance liquid chromatography (H PLC) with a fluorescent detector. The cytotoxic activity of PC12 cells was assay ed by means of MTT colorimetric method. RESULTS: 6-OHDA dose-d ependently increased glutamate release and decreased cell activity of PC12 cells , and the mGluRs ligands had no significant effect on that. CONCLUSION: The mGluR3 ligands has no protective effect on neurotoxicity of PC12 cel ls induced by 6-OHDA.
10.Survey and analysis of nutrient support drug utilization in cancer patients
Chinese Journal of Hospital Administration 1996;0(09):-
Objective To find out nutrient support drug utilization in cancer patients in our hospital. Methods An analysis was made by means of drug utilization research into the structure and rationality of nutrient support drug utilization in our hospital through an investigation into the detailed records of the dispensary from 1999 to 2002 and into 1 014 medical records from 2002. Results The variety, quantity, and cost of nutrient support drug utilization in the four years rose respectively by 58.82%, 71.66% and 28.16%. 49.30% of the cancer patients whose medical records were surveyed used such drugs. The quantity and person time ratio of PN and EN drug utilization was respectively 14∶1 and 13∶1, with malnourished patients accounting for 19.80%. Of the PN drugs whose DDD value could be determined, most had a DUI value that was greater than 1 whereas most of the EN drugs had a DUI value which was smaller than 1. Conclusion The variety, quantity, and cost of nutrient support drug utilization in the four years rose rapidly. The quantity and person time of PN drug utilization were much higher than those of EN drug utilization. Doubts could be cast in the handling of indications for nutrient support drug utilization in some patients and the doses of some nutrient support drugs prescribed were not so rational. Further explorations need to be made into the rational application of nutrient support treatment.