1.Prognostic evaluation of the tongue carcinoma surgery with preservation of the integrity of mandible and dentition
Chongqing Medicine 2015;(2):215-217
Objective To evaluate the prognosis of tongue carcinoma surgery with preservation of the integrity of mandible and dentition .Methods Sixty four cases of tongue carcinoma surgery from January 2009 to January 2011 were randomly collected (sev‐en missed ,57 enrolled) .Through retrospective case‐control study on retention of mandibular dentition and mandible rectangle radi‐cal operation of tongue carcinoma radical operation of tongue cancer resection were analyzed the clinical data including the survival rate ,reoccurrence rate and post‐operation life quality .The questionnaire was conducted by fourth edition of UW‐QOL .Results There were no significant difference in survival rates of the two groups of patients between retaining the mandible and dentition and resection of mandible rectangle (P>0 .05) .Two different types of surgical procedures for treatment of jaw had no correlation with the reoccurrence rate (P>0 .05) .The quality of life in retaining the mandible and dentition was significantly higher than the rectan‐gular groups (P<0 .05) .Conclusion Under a strict choice of surgical indications ,preserving radical operation of tongue carcinoma of the mandible and dentition could achieve good results of surgical treatment ,and can significantly improve patients′quality of life after operation .
2.Adverse events related to bevacizumab and the management principles in non-small cell lung cancer.
Chinese Journal of Lung Cancer 2010;13(6):563-567
Angiogenesis Inhibitors
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adverse effects
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Antibodies, Monoclonal
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adverse effects
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Antibodies, Monoclonal, Humanized
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Bevacizumab
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Carcinoma, Non-Small-Cell Lung
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drug therapy
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Hemorrhage
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chemically induced
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Humans
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Hypertension
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chemically induced
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Lung Neoplasms
;
drug therapy
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Proteinuria
;
chemically induced
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Thromboembolism
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chemically induced
4.Changes about joint injuries caused by train in recent years
Chinese Journal of Orthopaedic Trauma 2002;0(04):-
Objective To analyze the recent changes in features of joint injury caused by the fast running railroad train. Methods 1279 joint injuries o f the 10214 cases of train injury after the speeding up of the railway services from 1997 to 2003 were analyzed to find out their particular causal conditions, the severity of the injury, and the classification of the injuries, the correlat ion between which and recovery was also tested by AIS-ISS grading. Results Afte r the speeding up of the railway services, the incidence of joint injuries rose from 33.54% to 34.12%,the mortality rose from 22.88% to 30.33%,the multipl e joint severances rose from 19.84% to 34.19%,the open joint injury rose from 31.71% to 63.15%,and the mortality caused by multiple joint severances rose from 21.19% to 49.07%. Conclusions The incidence of multiple traumas resulted from the train is much higher than those resulted from other causes. Multiple t raumas caused by train are very difficult to deal with. The multiple organ dysfu nction syndrome (MODS) is a main factor to cause the death.
5.Microendoscopic discectomy for lumbar intervertebral disc herniation
Journal of Medical Postgraduates 2004;0(02):-
Objective:To investigate the operation technique and the effect of the posterior microendoscopic discectomy (MED) system on lumbar intervertebral disc hermiation (LIDH). Methods: We retrospectively reviewed and analyzed 25 cases of LVDH treated with the MED system from March 2004 to August 2005. Results: All the patients were ambulant 20 hours to 7 days (mean 2.4 days) after the operation, with a mean hospital stay of 5.2 days. And all were healed within the first stage except 1 case of infection. The patients were followed for 2-15 months (mean 6 months). Excellent results were achieved in 18 cases, good results in 5 and fairly good results in 2, the first two groups making up 92%. Conclusion: The key to successful MED with no complications is familiarity with the equipment, proper choice of indication, exact surgical location and skilful operation.
6.Observation of the Effect of the Fire and Leopard-spot Needling on Ankle Sprain
International Journal of Traditional Chinese Medicine 2009;31(1):52-
Objeetive To observe the effect of the fire and leopard-spot needling therapy in treating ankle sprain.Methods We randomly selected 59 ankle sprain cascs and divided them into 2 groups,with one contained 30 cases treated hy fire and leopard-spot needling therapy as the treatment group,and another contained 29 cases treated by computerized multa-function therapy apparatus as the control group.After 7 days'treatment,we observed the effects of each group.Results The results snowed that the effect of the treatment group was much better than the control group.Conclusion With the features of collateral vessel pricking and warming and activating meridians,fire and leopard-spot needling therapy can remove swelling and relieve pain rapidly.
7.Tissue engineered artificial nerves repair sciatic nerve defect in rats:an evaluation using horseradish peroxidase retrograde tracer technique
Chinese Journal of Tissue Engineering Research 2014;(29):4658-4662
BACKGROUND:We have previously prepared acellular nerve graft and implanted bone marrow mesenchymal stem cells into the graft, to successful y construct tissue engineered artificial nerves.
OBJECTIVE:Horseradish peroxidase nerve retrograde tracer technique was used to evaluate protective effects on sensory neurons fol owing sciatic nerve defect bridging with tissue engineered artificial nerves constructed by acellular nerve graft and bone marrow mesenchymal stem cells in rats.
METHODS:Adult, clean, healthy, male Sprague-Dawley rats were randomly assigned to three group:(1) Experimental group:Rat sciatic nerve detect was bridged by acellular nerve graft combined with bone marrow mesenchymal stem cells;(2) Blank control group:Rat sciatic nerve defect was bridged by acellular nerve graft;(3) Autologous nerve control group:Rat sciatic nerve defect was bridged by autologous nerve transplantation. Regeneration of sensory neurons in the spinal dorsal root ganglia was assessed using horseradish peroxidase nerve retrograde tracer technique at 12 weeks fol owing surgery.
RESULTS AND CONCLUSION:Sensory neuron regeneration in the spinal dorsal root ganglia at 12 weeks fol owing surgery was better in the experimental group compared with blank control group. No significant difference was detected between experimental group and autologous nerve control group. S-100 immunohistochemical staining in plantar skin showed brown positive reaction in each group. These findings indicate that tissue engineered artificial nerves constructed by acellular nerve graft and bone marrow mesenchymal stem cells have protective effects on sensory neurons in the spinal dorsal root ganglia, and can promote the recovery of sensory function and repair sciatic nerve defect in rats.
8.Common causes of headache and the treatment
Chinese Journal of Practical Internal Medicine 2001;0(06):-
Headache is a common clinical symptom.Some headache disorders belong to secondary category.Many intracranial disorders,such as head trauma,cerebral vascular diseases,intracranial tumors and inflammation,can lead to headache due to mass effect,inflammation reaction,stimulation of vasoactive substances and decreased intracranial pressure.Furthermore,many drugs and other substances,disorders of eyes,nose,ear,mouth,neck and other systemic disorders can also cause headache.Many headache disorders can be determined by detailed case history and physical examination.Blood test,lumber puncture,CT,MRI and other imaging examinations are necessary methods for finding the causes and the treatment of diseases.
9.Comparison of Clinical Efficacy of Amiodarone and Cedilanid in the Treatment of Paroxysmal Atrial Fibrillation with Intravenous Administration
China Pharmacy 2005;0(20):-
OBJECTIVE:To compare amiodarone and cedilanid in the treatment of paroxysmal atrial fibrillation(AF) with intravenous administration and control of heart rate.METHODS:47 AF patients were randomly given 150~600 mg amiodarone(amiodarone group,n=24) and 0.2~0.6 mg cedilanid(cedilanid group,n=23) intravenously.The outcome,change of heart rate and adverse drug reaction of 2 groups were observed.RESULTS:Effective rate of amiodarone group was significantly higher than that of cedilanid groups(P
10.Advances of study on tumor multi-drug-resistance and reversal agents
Chinese Pharmacological Bulletin 1986;0(06):-
The multi drug resistance(MDR) of tumor cells has become a difficult problem in the chemotherapy of tumor, meanwhile, the mechanism of MDR are various:relevant drugs with reversal effects have been discovered. This review will provide the most impossible mechanisms of MDR and some prospecting reversal drugs.