1.EFFECTS OF LYCIUM BARBARUM POLYSACCHARIDE ON CYTOKINE EXPRESSION IN HUMAN MONOCYTES
Acta Nutrimenta Sinica 1956;0(01):-
Objective: To explore the effects of Lycium barbarum polysaccharide (LBP-X) on IL-2 and TNF-? gene expressions in human peripheral blood mononuclear cells. Methods: RT-PCR (reverse transcription-polymerase chain reaction) was used to detect the gene expressions of IL-2 and TNF-?. Results: LBP-X at 5-40 mg/L upregulated the levels of IL-2 and TNF-? mRNA in human peripheral blood mononuclear cells after optimal time culture. Conclusion: The immunoenhancing effect of Lycium barbarum polysaccharide may be associated with its stimulation of IL-2 and TNF-? gene expressions.
2.Different Theoretical Perspectives in Coping Research
Chinese Journal of Clinical Psychology 2001;0(03):-
For decades, coping has undergone intensive investigation through different theoretical lens. In this paper, three theoretical standings in coping research were proposed:namely,the process theory, the trait theory and the situation theory. Relevant research and measurements were introduced. In the end, different perspectives were reevaluated and implication for further research was discussed.
3.Effect of Perfectionism on Depression and A Moderating Role of Personality
Chinese Journal of Clinical Psychology 2000;0(04):-
Objective: To explore the effect of perfectionism on depression using anxiety as a controllng variable,and to find possible personality moderators.Methods: 407 undergraduate students from 8 universities in Beijing and Xi'an completed a battery of questionnaires,including Frost Multidimensional Perfectionism Scale(FMPS),Beck Depression Inventory(BDI),Personality Adjective Checklist(PACL) and Self-rated Anxiety Scale(SAS).Results: Hierarchical Regression Analysis confirmed the effects of two negative perfectionism dimensions hesitating over actions and concerning over mistakes,on depression after controlling anxiety.The effect of organization on depression was moderated by the personality trait of cooperation.Conclusion: Dimensions of perfectionism have diverse effects on depression.Psychological intervention should be carried out according to individual characteristics.
4.The Theoretical and Empirical Study on the Demand of Rural Medical Services Based on Gravity Model
Chinese Health Economics 2014;(1):14-16
Objective: To study the influencing factors of the rural medical service demand. Methods: The gravity model of medical service demand was derived based on Individual utility function and profit objective function of medical institutions, and the data regression examine model of some county-level and district-level hospital were used. Results: According to the research, the main factors influenced the quantity of medical services come from medical supplies. With the increase of resident disposable income, the elasticity of demand for medical services decreased, while visiting distance of elasticity of demand for medical services increased. Conclusion: To increase the accessibility of medical service, it needs to set meeting the resident’s personal demand as the center, to promote the development of private hospitals. The scale of large hospitals should be limited so as to lead large-scale hospitals to separate low value-added medical services and to promote effective implementation of the treatment classification system.
5.EFFECT OF LYCIUM BARBARUM POLYSACCHARIDE ON ANTITUMOR ACTIVITY AND IMMUNE FUNCTION
Lu GAN ; Shenghua ZHANG ;
Acta Nutrimenta Sinica 1956;0(02):-
Objective: To study the antitumor effect of Lycium barbarum polysaccharide (LBP X) and its immunity regulating effect on S 180 bearing mice. Methods: S 180 bearing mice were used as animal model. The effect of LBP X on tumor weight and immune function was observed. Results: LBP X could inhibit the growth of S 180 effectively and increase thymus index, the macrophage phagocytic function, anti SRBC antibody secreted by the spleen cells, lymphocyte proliferation and CTL activity and decrease LPO markedly in S 180 bearing mice. Conclusion: The mechanism of tumor inhibition by LBP X was due to enhance the immune function.
6.Symptoms and causes of insomnia in amyotrophic lateral sclerosis
Chinese Journal of Neurology 2021;54(5):519-522
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease characterized by progressive loss of upper and lower motor neuron. Insomnia is one of the widespread but underappreciated non-motor symptoms in ALS patients, which may not only seriously affect patients′ quality of life, but also reflect the lesions of central nervous system in ALS. This review summarizes the insomnia symptoms reported in current ALS studies, and summarizes the somatic factors and central nervous system changes associated with insomnia in ALS patients, so as to provide ideas for the development of effective intervention measures and future research.
7.The Reliability and Validity of MBI-SS and Academic Characteristics Affecting Burnout
Ying ZHANG ; Yiqun GAN ; Yiwen ZHANG
Chinese Journal of Clinical Psychology 2000;0(04):-
Objective: To examine the reliability and validity of MBI-SS and discuss the academic characteristics that affect burnout. Methods: 353 undergraduate students were administrated MBI-SS and Academic Characteristic Survey. Results: Confirmatory factor analyses showed that the expected three-factor structure of the adapted versions of the MBI- Students Survey (including Exhaustion, Cynicism, and Reduced Efficacy) fitted to the data. Exploratory factor analyses showed that the Academic Characteristic Survey includes six dimensions. The result of Regression showed that 44.4% variance of student burnout can be explained by Academic Characteristics. Conclusion: Student burnout includes three dimensions: Exhaustion, Cynicism and Reduced efficacy. Academic self-efficacy,academic stress,relationship with teachers and relationship with fellow students are significant predictors for student burnout.
8.Application of monoclonal antibody pool against Bacteroides fragilis and Clostridium perfringens in rapid diagnosis in surgical infection
Yaping ZHANG ; Lu GAN ; Shan CHANG
Journal of Third Military Medical University 2001;23(2):224-226
Objective To prepare monoclonal antibody (McAb) pool against Bacteroides fragilis and Clostridium perfringens and evaluated its effect in rapid diagnosis in surgical infection. Methods After the preparation of monoclonal antibodies against B. fragilis and C. perfringens, 191 specimens collected from infectious patients was detected with indirect immunofluorescent antibody (IFA) and enzyme labeled antibody (ELA). The results were compared with routine cultural method (CM). Results Among the 191 specimens, 53 (27.7%), 55 (28.8%) and 25 (13.1%)strains of B. fragilis were detected with IFA, ELA and CM respectively, and for C.perfringens, 12(6.3%), 11(5.8%), and 6(3.1%) strains were found. The detectable rate of anaerobic bacteria by IFA and ELA was higher than by CM, but no difference was found between these 2. Conclusion The self-made McAb pool against B.fagilis and C.perfringens might be a rapid, specific, sensitive and simple McAb pool for detecting B.fragilis in surgical infection and C.perfringens in wartime.
9.Psychological Training of Self Consistency and Congruence in Army Men
Jingli GAN ; Wanheng ZHANG ; Yanan ZHAO
Chinese Mental Health Journal 1991;0(05):-
Objective:To explore the effect of psychological training on self consistency and congruence of army men. Methods:532 army men were tested by Self Consistency and Congruence Scale(SCCS)、EPQ、simplified coping style questionnaire(SCSQ)and SCL-90. Results:There were significant difference in score of SCCS between army men group and norm.There were significant correlation between factor scores of SCCS and scores of EPQ,SCSQ and SCL-90. After psychological training,the study group had higher score in flexibility than that of norm. The study group had higher score in flexibility and positive coping style than control group,and lower scores in P and N of EPQ,total score,obsessive-compulsive,interpersonal sensitivity,anxiety,hostility,paranoid ideation and psychoticism of SCL-90 than control. Conclusion:Self consistency and congruence level of army men were associated with personality, coping style and mental health. The psychological training has effect on balancing personality,facilitating self consistency,improving coping style and the psychological status of army men.
10.Effects of Mental health education on mental health of middle school students
Jingdong LIU ; Xiaodong ZHANG ; Shouyun GAN
International Journal of Traditional Chinese Medicine 2011;33(1):31-32,62
Objective To explore the effects of psychological health education on mental health status of middle school students. Methods All middle school students were randomly divided into 2 groups by cluster sampling, a interventional group and a control group. 28 students in the intervention group received group psychological consultation for two months, 30 students in the control group received no therapies.Changes of active respond and negative response subscales(ARNRS), communication anxiety scale (IAS),accommodate others scale(AOS), self-rating depression scale(SDS)were compared before and after the intervention in both groups. Results After group counseling, ARNRS, IAS, AOS, SDS in the interventional group was significantly changed compared with both pre-counseling and the control group, with P<0.05~0.0001 and P<0.05~0.0001, respectively. Conclusion Community mental health education can enhance middle-school student's psychological health level.