Objective: To research on the design and development of the Oncology Follow up System base on Oncology Information System. Methods: To analyze the workflow of follow up. Design the architecture of the system software. Discuss the development of the important modules such as the interface, the follow up reminder, the follow up recorder and the follow up searcher. Results:To develop the follow up system of the radiotherapy department, including the interface for oncology information system, the follow-up remind module, the follow-up input and the follow-up query module. Conclusion:Through building the follow up system of the radiology department, can provide great help to doctor’s clinical work, improve the doctor’s working and researching efficiency, and improve the patients’ satisfaction.

To study the efficacy of CAG regimen used in 35 cases of newly diagnosed acute myeloid leukemia in elder-ly patients. Methods:Totally 35 cases of elderly patients with acute myeloid leukemia were randomly divided into two groups. The pa-tients in the control group (15 cases) were treated with standard chemotherapy treatment, while the CAG regimen group (20 cases) was treated with CAG regimen (cytarabine, aclarubicin and granulocyte colony-stimulating factor). After one treatment course, the chemotherapy efficacy was observed, and the neutrophil and platelet recovery time and the incidence of adverse reactions in the two groups were compared. Results:The treatment efficacy of the CAG regimen group was 90%, which was higher than that of the control group (60%, P<0. 05). The neutrophil and platelet recovery time of the CAG regimen group was significantly shorter than that of the control group (P<0. 05). The incidence of adverse reactions in CAG regimen group was much lower than that of the control group(P<0. 05). Conclusion:The efficacy of CAG regimen used in the 35 cases of newly diagnosed acute myeloid leukemia in elderly pa-tients is promising, which can effectively control the progression of the disease and accelerate blood cell recovery with high safety.

Objective To understand the current situation of medical postgraduates'!honesty edu-cation, find the weak point and explore new ways of the honesty education. Methods The honesty educa-tion survey questionnaire was designed and conducted to the postgraduates of Grade 2014 in Peking University Health Science Center. The research contents included the basic information of postgraduates, honesty cognition, clean and self-discipline, honesty education, the recommendation of honesty education and the application of honesty education carrier. 1 038 questionnaires of a total of 1 142 questionnaires were recovered and the recovery rate was 90.9%. EPIData3.0 software was used for double entry and database establishment, and SPSS 19.0 software for statistical treatment. Results 82.3% (854) of the postgraduates recognized the work of clean government, but only 62.1% (644) of the postgraduates concerned about it. 78.3% (813) of the postgraduates expressed hatred for the dishonest behavior and hoped to eliminate it. 77.6%(806) postgraduates often paid attention to honest education content which was pushed by the new media. 16.5% (171) postgraduates thought that the new media was very important to the honest cognition. Conclusions We should pay more attention to medical postgraduates'!honesty education, find its weak points according to the investigation and make full use of the network and new media. And at the same time we should combine the actual environment to establish a hierarchy of honesty education system, and carry out honesty education through total environment which contains the school administrators, instructors/head teachers and tutors.

Many genetic events have been described to be involved in the development of tumor,but a lot of recent researches proved that epigenic events also played an important role in it.DNA methylation is one of the common modification of epigenic events,the binding of methyl-CpG binding domain proteins has been shown to lead to transcriptional repression of many tumor repressor genes.

OBJECTIVE To investigate the protective effect and its frequency selection of dopamine on the inner cell in cochlea when exposed to white-noise;In order to offer an important step on understanding of negative protective modulation of dopamine in the cochlear auditory afferent nerve. METHODS Forty guinea pigs were randomly divided into 4 groups and whole intracochlear perfusions were performed. ① exposed to the 100dB white-noise; ② perfused with artificial perilymph solutions; ③exposed to the white-noise and perfused with artificial perilymph solutions; ④exposed to the white-noise and perfused with Artificial perilymph solutions containing 1mmol/L dopamine. Compound action potential(CAP)evoked by different frequencies tone pip, and cochlear mirophonics(CM)evoked by 4kHz tone burst were recorded from the round window of guinea pigs before and 2h after perfusion. RESULTS In the groups exposed to the white-noise, the CM amplitude and the linearity of input-output function both significantly decreased at 2h(P

Objective To investigate the sensitivity of Heidelberg Retina Tomography (HRT-Ⅱ)parameters on the early optic nerve change of glaucoma head. Design Cross-sectional study. Participants Twenty-one patients (36 eyes) with big cupped disc(C/ D≥0.7) and twenty-seven patients (31 eyes) with early glaucoma (C/D≥0.7, MD≤3dB) were studied. Methods All patients underwent visual field and HRT-Ⅱ examination to get parameters of optic nerve head. T test was used to compare the parameters of optic disc between big cupped disc and early glaucoma. Main Outcome Measures HRT Ⅱ parameters included disc area, cup area, rim area, cup volume, rim volume, C/D area ratio, mean cup depth, maximum cup depth, cup shape measure, height variation contour, mean RNFL thickness and RNFL cross sectional area. Results Statistics analysis with T test (t=2.247-3.714, P=0.000-0.028) showed there were significant differences of rim area, rim volume, mean retinal nerve fiber layer thickness, sectional area of retinal nerve fiber layer between big cupped disc and early glaucoma. Conclusions We can pay attention to those parameters with HRT- Ⅱ to distinguish patients with big cupped disc and early glaucoma.

Objective:Through the construction of the Bank-Hospital connecting project, the enduring problems in clinic such as the long waiting time at registration, check out, payment, and other non-clinic issues are solved. Meanwhile, the clinic medication procedure is further regulated, which provides a faster medical assistance service for patients and elevates the ability to apply medical informationization.Methods:Based on the current HIS platform, the banking and mobile systems connected as a whole network and constructed the banking-medication platform. Results: The waiting time of patients is largely reduced by expanding the channels of registration, applying multiple cards as medication card, and introducing local charging, self-payment systems at every floor, and mobile intelligent platform.Conclusion: The Bank-Hospital connecting project brings convenience to patients and increases our efficiency.

Academic ethics is closely related to the construction of the world class disciplines,the academic ethics of university mentors and their graduate students are especially important to the development of disciplines and Universities.This article was based on a survey which used two-way evaluation conducted at Peking University Health Science Center,investigated the cognition,current status,misconduct and possible causes,as well as related trainings of academic ethics between mentors and mentees,furthermore,this article also analyzed the application of mentor-mentee two-way evaluation in the academic ethics trainings for post graduate students.

Objective: To construct a core competency training indicator system for high-level public health talents using the Delphi method, so as to provide insights into optimization of high-level public health talents training. Methods: Based on review of publications pertaining to core competency training for high-level public health talents, in combination with public health priorities and development needs in China, a preliminary indicator system was constructed. Twenty public health experts were invited for two rounds of Delphi expert consultation. Indicators were screened based on the frequency of full marks, mean score and coefficient of variation (CV), and the weight of indicators was determined using the Entropy weight method. The effectiveness of the Delphi expert consultation was evaluated using the active degree, authority coefficient and the consistency degree. Results: Twenty experts participated in the consultation, including 12 men, and there were 6 experts at ages of 30 to 39 years, 8 at ages of 40 to 49 years, and 6 at ages of 50 years and older. There were 17 experts with an educational level of master and above, 19 with senior professional titles and all experts had working experiences for 10 years and longer. The active degrees were 95.24% and 100.00% for two rounds of consultations, and the overall authority coefficient was 0.87. Following two rounds of consultations, all CVs were reduced to below 0.25, and the coordination coefficients were all statistically significant (P<0.05), with a higher coordination coefficient in the second round of consultation than in the first round. The constructed core competency training indicator system for high-level public health talents included four primary indicators, including health protection, health service improvement, health promotion, and essential quality, with weights of 0.388, 0.310, 0.122 and 0.180, 11 secondary indicators, with high weights seen for protection of human health from threats (0.178), monitoring and assessment of health service utilization (0.157) and promotion of health service quality and access (0.112), and 70 tertiary indicators, with high weights seen for Chinese writing (0.038), capability for health policy suggestions (0.034) and global perspective (0.030). Conclusion The core competency training indicator system for high-level public health talents constructed in this study may provide insights into training of high-level public health talents.