OBJECTIVE:To probe into the status quo and the tendency of the utilization of the anti-osteoporosis drugs in hospitals along the Yangtze valley. METHODS: The utilization of the anti-osteoporosis drugs in 177 hospitals of 6 cities along the Yangtze valley during 2004～2008 was analyzed statistically in respect of the orders of consumption sum and defined daily dose (DDD). RESULTS: The total amount of the drugs used for osteoporosis in the hospitals of the Yangtze valley showed year-on-year increase,and its proportion in the total remained at around 1.16% on the consumption sum list. The consumption sum of Diphosphonates showed sharp increase,many of its subcategories had forced into the top 10 places on the list of consumption sum and their rankings were moving forward steadily. Alfacalcidol and Calcitonin dominated the first two places over the 5 years. The top 10 manufacturers in terms of the sales sum of the drugs for osteoporosis were mainly foreign investment manufacturers and joint ventures. CONCLUSION: With the aging of the population and the strengthening of public awareness on health,the drugs used for osteoporosis enjoy a potential market,especially to domestic products and domestic manufacturers.

Humans ; Inlays

The expression of genes have an important effect to gastric cancer chemotherapy.Some genes are related the therapeutic efficacy of drugs,some genes are related the untoward effects of drug,and some genes are related the sensitivity of the tumor to drug.Chemotherapy related genes may play an important guiding role to improve the curative effect of chemotherapy patients.In recent years,the gastric cancer chemotherapy related genes have made great progress,especially in platinum,fluorouracil,paclitaxel and targeted medicine related genes.

This research applied the theory of customer satisfaction model in the evaluation of the clinical information system. By means of qualitative and quantitative methods, it made validity and reliability measurement on the measurement tools in use. In addition, it extracted the structure validity of the factor regulating scale via a factor analysis, and developed the scale for clinical information system measurement These efforts provided the hospitals with the useful measurement tool to improve their information system, promoting positive and practical hospital informationziation.

Child ; Child, Preschool ; Humans ; Hypersensitivity, Immediate ; prevention & control ; Infant ; Primary Prevention

Anti-Asthmatic Agents ; therapeutic use ; Asthma ; diagnosis ; drug therapy ; Emphysema ; Female ; Humans ; Male

Advisory Committees ; Humans ; Long QT Syndrome ; prevention & control ; therapy ; Practice Guidelines as Topic

Asthma ; diagnosis ; therapy ; Child ; Chronic Disease ; Cough ; diagnosis ; therapy ; Humans

Asthma ; diagnosis ; therapy ; Child ; Humans

OBJECTIVE:To study the release characteristics of Evening primrose oil microspheres in vitro. METHODS:UV spectrophotometry was adopted to determine the accumulated release of microspheres under different media,and the drug release behaviors in vitro were fitted using zero-order,first-order and Higuchi equations. RESULTS:The accumulated release of microspheres in the gastrointestinal liquid (within 6 h) was up to(92.84?0.35)%;under the media of artificial gastric juice,the release of drug conformed to Higuchi equation:Q=5.941t1/2—11.083(r=0.991 7); under the media of artificial intestinal juice,the release of drug was in line with first-rate equation:ln(100—Q)=—0.487 4t+4.588(r=0.996 4). CONCLUSION:This method is simple,accurate and reproducible,and it can be used for the determination of the release rate of the Evening primrose oil microspheres.