1.Effects of rapid weight reduction on the body water and nitrogen balance in wrestlers.
YUMI MUKASA ; KAYOKO KANEKO ; GORO KOIKE ; KOJI SAKURAMA ; RYOHEI YURUGI
Japanese Journal of Physical Fitness and Sports Medicine 1986;35(3):152-160
Six wrestlers, whose body weights should be reduced 4-11% in relatively short period of time to be acknowledged for intercollegeate 62 kg class competition, were selected and their daily food intakes in regulation, reduction through recovery period of body weights were estimated. Simultaneously, the weights of whole urine and feces were estimated, and some urine components were analysed.
Nutrients intake except calsium and iron were maintained allowance level in regulation period, and reduced through reduction period. On third day of recovery period, the body weights were recovered to their own level, but through the period, only the intake of energy, water, sodium and vitamin A were recovered to the level of regulation period. Personal deviations in their intakes of vitamin B complex and C were distinkt, and the iron intake was under level through all period.
The average body water contents was 68%, estimated by D20 method. Negative water and nitrogen balance through regulation and reduction period turned to positive in recovery period, but not completely recovered to their nomal level.
2.NUTRITIONAL AND PHYSIOLOGICAL STUDIES ON THE RAPID WEIGHT REDUCTION IN WRESTLERS
MICHIKO WATANABE ; YUMI MUKASA ; HISANO SUZUKI ; KAYOKO KANEKO ; GORO KOIKE ; KOJI SAKURAMA ; HIDEO FUJIMOTO ; SEIJI IKAWA ; ITSUO SASABUCHI ; HIROMASA KITA ; RYOHEI YURUGI
Japanese Journal of Physical Fitness and Sports Medicine 1984;33(1):40-51
Seven wrestlers, whose body weights should be reduced about ten per cent in relatively short period of time to be acknowledged for intercollegeate competition, were selected, and their daily food intakes in reduction through recovery period of body weight were estimated. Simultaneously, some blood and urine components were analysed, performance capacities (grip and back strength power) were measured, and gross balances of nitrogen and potassium were calculated as the difference between their intakes and urinary outputs, to discuss the influence of rapid weight reduction.
For several days of the last stage of reduction period, the average intakes per kg body weight per day were about 20 kcal for energy, about 1.7 g for protein, about 20 g for food moisture and drinking water, total intakes per day were about 2 g for sodium and about 1 g for potassium respectively.
During about seven days of recovery period, these intakes were increased to higher level, which were as average about 60 kcal for energy, about 2 g for protein, 46-73 g for food moisture and drinking water per kg body weight, about 5 g for sodium and about 3 g for potassium per day, respectively.
During reduction period, the negative balances of nitrogen and potassium, slight reduction of performance capacities and dehydration symptoms in blood components (Ht value, and contents of Hb, plasma protein plasma urea nitrogen) were observed.
During recovery period, the body weights were recovered rapidly to normal level, nitrogen and potassium were turned to positive balance, but some components (Ht value, plasma protein) were not completely recovered to their normal level.
As far as the average food composition in recovery period was concerned, not so remarkable deficiency was observed, but the personal deviations in their intakes were distinct. From these results, it is suggested that by better balanced combination of food intake, personal body conditions of these young sportsmen with high physical strength would recover to their normal level more quickly and more completely.
3.Albumin-Bilirubin Score Predicts Tolerability to Adjuvant S-1 Monotherapy after Curative Gastrectomy
Takashi MIWA ; Mitsuro KANDA ; Chie TANAKA ; Daisuke KOBAYASHI ; Masamichi HAYASHI ; Suguru YAMADA ; Goro NAKAYAMA ; Masahiko KOIKE ; Yasuhiro KODERA
Journal of Gastric Cancer 2019;19(2):183-192
PURPOSE: Due to adverse events, dose reduction or withdrawal of adjuvant chemotherapy is required for some patients. To identify the predictive factors for tolerability to postoperative adjuvant S-1 monotherapy in gastric cancer (GC) patients, we evaluated the predictive values of blood indicators. MATERIALS AND METHODS: We analyzed 98 patients with pStage II/III GC who underwent postoperative adjuvant S-1 monotherapy. We retrospectively analyzed correlations between 14 parameters obtained from perioperative routine blood tests to assess their influence on the withdrawal of postoperative adjuvant S-1 monotherapy, within 6 months after discontinuation. RESULTS: Postoperative adjuvant chemotherapy was discontinued in 21 patients (21.4%) within 6 months. Univariable analysis revealed that high preoperative albumin-bilirubin (ALBI) scores had the highest odds ratio (OR) for predicting the failure of adjuvant S-1 chemotherapy (OR, 6.47; 95% confidence interval [CI], 2.08–20.1; cutoff value, –2.696). The high ALBI group had a significantly shorter time to failure of postoperative adjuvant S-1monotherapy (hazard ratio, 3.48; 95% CI, 1.69–7.25; P=0.001). Multivariable analysis identified high preoperative ALBI score as an independent prognostic factor for tolerability (OR, 10.3; 95% CI, 2.33–45.8; P=0.002). CONCLUSIONS: Preoperative ALBI shows promise as an indicator associated with the tolerability of adjuvant S-1 monotherapy in patients with pStage II/III GC.
Chemotherapy, Adjuvant
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Drug Therapy
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Gastrectomy
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Hematologic Tests
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Humans
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Odds Ratio
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Retrospective Studies
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Stomach Neoplasms