1.Advances in the research of microRNA in Orchidaceae.
Zihan XU ; Yue CHEN ; Fengrong HU
Chinese Journal of Biotechnology 2022;38(1):66-76
As a class of small non-coding RNAs, microRNA (miRNA) is widely present and plays important regulatory roles in plant growth, development and stress response. Based on the mechanism of miRNAs in plants, we review the identification of miRNAs in some genera of Orchidaceae, the specific functions of several miRNAs and other relevant studies on miRNAs in the last decade, in order to provide a reference for better understanding function and regulatory network of small RNAs in orchids.
MicroRNAs/genetics*
;
Orchidaceae/genetics*
;
Plants/genetics*
2.Genetics of Branchal Asthma.
Tuberculosis and Respiratory Diseases 2006;60(4):391-396
3.Genetics of Epilepsy.
Journal of Korean Epilepsy Society 2003;7(2):91-95
4.Moleculan Genetics of Glucocorticoid Remediable Aldosteronism.
Journal of Korean Society of Endocrinology 1997;12(3):341-345
No abstract available.
Genetics*
;
Hyperaldosteronism*
6.Genetics of Atopy and Asthma.
Pediatric Allergy and Respiratory Disease 1999;9(4):343-350
7.Genetics in Epilepsy.
Journal of the Korean Child Neurology Society 1999;6(2):205-214
8.The current status and future prospects of DNA computing.
Shan YANG ; Jinyu LI ; Yujun CUI ; Yue TENG
Chinese Journal of Biotechnology 2021;37(4):1120-1130
As the demand for high-performance computing continues to grow, traditional computing models are facing unprecedented challenges. Among the many emerging computing technologies, DNA computing has attracted much attention due to its low energy consumption and parallelism. The DNA circuit, which is the basis for DNA computing, is an important technology for the regulation and processing of the molecular information. This review highlights the basic principles of DNA computing, summarizes the latest research progress, and concludes with a discussion of the challenges of DNA computing. Such integrated molecular computing systems are expected to be widely used in the fields of aerospace, information security and defense system.
DNA/genetics*
9.Online and offline mixed teaching mode of medical genetics.
Gang SU ; Jiong LI ; Hua WU ; Peiqiang LI ; Xiaodong XIE
Chinese Journal of Biotechnology 2021;37(8):2967-2975
Online courses are an indispensable part of medical teaching in the new era. Online courses have good prospects, although also with certain problems in practice. As an important basic medical course, medical genetics has both basic theoretical knowledge and clinical cases, involving basic principles and the latest developments. A single online course or offline teaching model cannot meet the needs of subject development and training a new generation of medical professionals. Therefore, actively exploring the online and offline hybrid teaching model is one of the important topics in the current medical teaching reform.
Genetics, Medical
10.Genotypic profiles of virulent genes detected among the Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa isolated from swiftlets in Borneo
Sui Sien Leong ; Samuel Lihan ; Hwa Chuan Chia
Malaysian Journal of Microbiology 2020;16(4):275-284
Aims:
The occurrence of multiple pathogenic Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa
are important nosocomial and hazardous infection clinically challenge worldwide. Thus, the aim of this study was to
screen for the virulent genes profiles to ascertain their prevalence in swiftlets in Borneo.
Methodology and results:
The Enterococci, E. coli and P. aeruginosa bacteria were isolated from the swiftlets’ faeces
and air inside swiftlet houses, which located in the Southern, Central and Northern regions of Borneo. The isolates were
identified to the species level by 16S rRNA sequencing assay. Specific primers were designed for detection of the
potential virulence genes in E. faecalis (ace, AS, efaA and gelE), E. coli (stx) and P. aeruginosa (oprL) by PCR assay. A
total of 38 Enterococci, 26 of E. coli and 2 of P. aeruginosa fecal and airborne bacteria were identified. Sixty-seven
percent of E. faecalis isolates were detected positive for four virulence genes, 27% possessed three (AS, efaA, gelE)
genes and 6% possessed two (ace, AS) genes. There were no stx genes detected among all the E. coli isolates. The
oprL gene was detected in all the P. aeruginosa isolates.
Conclusion, significance and impact of study
Virulence genes are important in the pathogenesis of both clinical and
avian infections which considered to be a serious public health threat. The high incidence of virulence genes detection in
E. faecalis and P. aeruginosa indicates these genes were widely disseminated among the bacteria found in swiftlet
houses, suggesting the important issues in the pathogenesis of infections and diseases which may cause potential
health risks to humans.
Virulence--genetics