1.The importance of ophthalmic signs in the diagnosis of suprasellar meningioma- a case report
AK Tan ; PS Mallika ; S Aziz ; T Asok ; G Intan
Malaysian Family Physician 2009;4(1):26-29
A forty-two year old lady presented with gradual, painless, progressive blurring of vision of her left eye for four months. There were no other associated ocular or systemic complaints. Examination showed decreased visual acuity in both eyes and a pale optic disc on the left side. Visual field examination revealed a temporal field defect of the right eye which aroused the
suspicion of an intracranial mass lesion. MRI of her brain revealed a suprasellar meningioma. We would like to emphasize the importance of visual field examination of both eyes in patients presenting with unilateral loss of vision.
2.Ethambutol ocular toxicity in a patient with pulmonary tuberculosis - A case report
AK Tan ; PS Mallika ; S Aziz ; T Asok ; G Intan
Malaysian Family Physician 2008;3(2):87-90
Purpose. To highlight the importance of using the Farnsworth Panel D-15 Hue test in colour vision testing in patients on ethambutol treatment.
Case Report. A 70 year-old lady received ethambutol as part of her anti-tuberculous regime. She developed blue-yellow colour defect detectable with the Farnsworth Panel D-15 Hue test, but not with the Isihara Pseudoisochromatic Plates. Ethambutol was immediately discontinued from her anti-tuberculous regime. Two months later, her colour vision returned to normal.
Conclusion. This case report illustrates the importance of regular monitoring of patients receiving ethambutol for blue-yellow colour defect using the Farnsworth Panel D-15 Hue Test.
3.PAEDIATRIC OCULAR TRAUMA IN KUCHING, SARAWAK, MALAYSIA
AK Tan ; PS Mallika ; T Asokumaran ; S Mohamad Aziz ; G Intan
Malaysian Family Physician 2011;6(2&3):68-71
Purpose: To evaluate the demography, aetiology, type and outcome of paediatric ocular trauma in tertiary centre in Malaysia.
Method: We retrospectively studied 118 eyes from 117 patients over a period of 36 months (January 2006 to December 2008).
All ocular injuries in patients aged 12 and below seen in the Ophthalmology Department for the first time were included in this
study.
Results: Mean age of patients was 6.1±3.0 years. 68 cases (58.2%) occurred in pre-school children, whereas 49 (41.9%) in
school-aged children. Boys accounted for 65.8% of cases. There was no predilection for either right or the left eye. 47% of cases
(56 patients) occurred in Malay. Most of the injuries took place at home when the children were alone (p<0.05). Sharp objects
were the commonest cause (45 cases, 38.1%). The majority of cases (103, 87.3%) were considered preventable. The
frequency of open and closed globe injury was similar. Hyphema was more common in closed globe injury compared to open
globe injury (p<0.05). Other associated injuries such as cataract, vitreous hemorrhage and retinal hemorrhage are similar
between the two groups. Visual outcome is generally poor with only 34 eyes (28.8%) had no visual impairment.
Conclusion: Ocular trauma in children is an important cause of visual loss. Most cases occurred at home and were preventable.
Prevention through education is the best approach.
4.Diabetic Retinopathy and the effect of pregnancy
PS Mallika ; AK Tan ; S Aziz ; T Asok ; SAR Syed Alwi ; G Intan
Malaysian Family Physician 2010;5(1):2-5
Pregnancy is associated with increased risk of development and progression of diabetic retinopathy (DR). Although pregnancy does not have any long term effect on DR, progression of retinopathy changes occur in 50%-70% of cases. The greatest risk of worsening occurs during the second trimester and persists as long as 12 months postpartum. The other factors found to
be associated with its progression include duration of the diabetes, severity of retinopathy at conception, hyperglycaemic control, anaemia and progression of coexisting hypertension. Because of the increased risk of progression of the disease in pregnancy, conception should be delayed till the ocular disease is treated and stabilized and laser photocoagulation should
be promptly instituted in all cases of severe non-proliferative retinopathy and should not be delayed till the patient develops early proliferative changes. Good diabetic control before and during pregnancy can help prevent this increase in the progression
and serious vision loss.
5.Comparison between the panoptic opthalmoscape and the conventional direct opthalmoscape in the detection of sight threatening diabetic retinopathy: the Kuching diabetic eye study
AK Tan ; PS Mallika ; S Aziz ; T Asokumaran ; G Intan ; HA Faridah
Malaysian Family Physician 2010;5(2):83-90
Objective: To determine the sensitivity and specificity of the conventional direct ophthalmoscope and the PanOptic
ophthalmoscope in the detection of sight threatening retinopathy, as well as the “Ease of Use” of these equipments.
Methods: 200 diabetics, newly referred from primary health physicians were examined. Fundus examinations were performed with pupil dilatation in a dark room. The examinations were performed by a single investigator using the PanOptic ophthalmoscope, the conventional direct ophthalmoscope and slit lamp biomicroscopy.
Results: The overall sensitivity in detecting sight threatening retinopathy using the conventional direct ophthalmoscope was 73.2% (95% CI: 57.1-85.8%), specificity 93.7% (95% CI: 88.7-96.9%). For PanOptic ophthalmoscope, the overall sensitivity in detecting sight threatening retinopathy was 58.5% (95% CI: 42.1-73.7%), specificity 93.7% (95% CI: 88.7-96.9%). The conventional direct ophthalmoscope was 1.38 times (95% CI: 1.17-1.61 times) as easy to use compared to the PanOptic ophthalmoscope.
Conclusion: The PanOptic ophthalmoscope is not superior to the conventional direct ophthalmoscope for the screening of
Sight Threatening Retinopathy.
6.Thyroid associated ophthalmopathy- a review
PS Mallika ; AK Tan ; S Aziz ; SAR Syed Alwi ; MS Chong ; R Vanitha ; G Intan
Malaysian Family Physician 2009;4(1):8-14
Thyroid associated ophthalmopathy is an autoimmune disorder affecting the orbital and periorbital tissues. Hyperthyroidism is commonly associated with thyroid associated ophthalmopathy, however in 5% to 10% of cases it is euthyroid. Genetic, environmental and endogenous factors play a role in the initiation of the thyroid ophthalmopathy. Smoking has been identified
as the strongest risk factor for the development of the disorder. The pathogenesis involves activation of both humoral and cell mediated immunity with subsequent production of gycoaminoglycans, hyaluronic acid resulting in oedema formation, increase
extraocular mass and adipogenesis in the orbit. The natural history of the disease progresses from active to inactive fibrotic stage over a period of years. Diagnosis is mainly clinical and almost all patients with ophthalmopathy exhibit some form of
thyroid abnormality on further testing. Treatment is based on the clinical severity of the disease. Non-severe cases are managed by supportive measures to reduce the symptomatology and severe cases are treated by either medical or surgical decompression. Rehabilitative surgery is done for quiescent disease to reduce diplopia and improve cosmesis.
7.Neonatal conjunctivitis - A review
PS Mallika ; T Asok ; Faisal HA ; S Aziz ; AK Tan ; G Intan
Malaysian Family Physician 2008;3(2):77-81
Ophthalmia neonatorum remains a significant cause of ocular morbidity, blindness and even death in underdeveloped countries. The organisms causing ophthalmia neonatorum are acquired mainly from the mother’s birth canal during delivery and a small percentage of
cases are acquired by other ways. Chlamydia and Neisseria are the most common pathogens responsible for the perinatal infection. Fortunately in most cases, laboratory studies can identify the causative organism and unlike other form of conjunctivitis, this perinatal
ocular infection has to be treated with systemic antibiotics to prevent systemic colonization of the organism. Routine prophylaxis with 1%
silver nitrate solution (crédés method) has been discontinued in many developed nations for the fear of development of chemical conjunctivitis
8.Pattern of ocular trauma in Kuching, Malaysia
PS Mallika ; AK Tan ; T Asok ; HA Faisal ; S Aziz ; G Intan
Malaysian Family Physician 2008;3(3):140-145
Objectives: To analyze the causes and characteristics of ocular injuries presenting to Sarawak General Hospital (SGH), Kuching.
Design: It is a prospective hospital-based study done for a period of 1 year.
Setting: Department of Ophthalmology, Sarawak General Hospital, Malaysia.
Participants: All ocular injury patients seen for the first time in the Eye Department during the period January 2006 to December 2006 were included in the study. Eye injury patients on follow-up and treated elsewhere were excluded.
Results: A total of 233 patients, and 257 eyes, were studied. Men had six-fold higher rates of injury than women. The average age of presentation was 30 years. The predominant age group was between 21-30 years, 26.2 % (n=61). Eye injuries related to work were seen in 36.9% of patients. There was a gross negligence in the use of personal protective devices in the work-related group. The common settings in which the injuries occurred included home 34.3% (n=80) and industrial premises 31.8% (n=74). Assault-related injuries 7.7% (n=18) were seen mostly among young men in the age between 20-30 years. The initial presenting visual acuity of the patients with blunt ocular trauma was better than penetrating
injury.
Conclusion: Ocular injuries were common in young males. Work related eye injuries were noted in a significant number of cases. Health education and preventive strategies both in the working place and at home will help to decrease the occurrence of ocular injuries.