1.Wandering humeral head mimicking a breast mass.
Gerald J S Tan ; Andrew G S Tan ; Wilfred C G Peh
The Medical journal of Malaysia 2008;63(2):164-5
A 74-year-old woman was incidentally found to have a left breast mass. The mass could not be adequately compressed to be visualized on mammography. Ultrasonography showed a heavily-calcified rounded mass in the left axillary tail of the left breast. Chest radiograph confirmed that the mass was a migrated humeral head. Remotely-displaced fracture-dislocations of the humeral head are very rare and to our knowledge, displacement into the breast, clinically mimicking a breast mass, has not been previously described.
Mass in breast
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Head
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Mass, NOS
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Wandering
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Breast
2.The efficacy of oral Micronized Progesterone versus Medroxyprogesterone Acetate in the control of mild to moderate abnormal uterine bleeding - ovulatory Dysfunction (AUB-O) in adolescents: An open label randomized controlled trial
Angeline G. Santos ; Mary Carmona-Tan ; Ma. Socorro C. Bernardino
The Philippine Children’s Medical Center Journal 2023;19(2):75-86
Objectives:
To determine the efficacy of micronized oral progesterone (OMP) versus
Medroxyprogesterone Acetate (MPA) in the control and regulation of mild to moderate abnormal
uterine bleeding in adolescents with ovulatory dysfunction.
Materials and Methods
This is an open labelled Randomized Controlled Trial. Fifty
patients with mild to moderate abnormal uterine bleeding were randomized to treatment with
Medroxyprogesterone Acetate or Oral Micronized Progesterone.
Medroxyprogesterone Acetate
3.Evaluation of DNA and RNA Extraction Methods
C S Edwin Shiaw ; M S Shiran ; Y K Cheah ; G C Tan ; A R Sabariah
The Medical Journal of Malaysia 2010;65(2):133-137
This study was done to evaluate various DNA and RNA
extractions from archival FFPE tissues. A total of 30 FFPE
blocks from the years of 2004 to 2006 were assessed with
each modified and adapted method. Extraction protocols
evaluated include the modified enzymatic extraction
method (Method A), Chelex-100 extraction method (Method
B), heat-induced retrieval in alkaline solution extraction
method (Methods C and D) and one commercial FFPE DNA
Extraction kit (Qiagen, Crawley, UK). For RNA extraction, 2
extraction protocols were evaluated including the
enzymatic extraction method (Method 1), and Chelex-100
RNA extraction method (Method 2). Results show that the
modified enzymatic extraction method (Method A) is an
efficient DNA extraction protocol, while for RNA extraction, the enzymatic method (Method 1) and the Chelex-100 RNA extraction method (Method 2) are equally efficient RNA extraction protocols.
4.Two cases of Ex utero intrapartum treatment (EXIT) in UP-PGH.
Catabijan Carlo G. ; Simon Edgard M. ; Gumintad Gina O. ; Tan Maria Lucresia A. ; Marcial Karmi Margaret G. ; Castillo June Cathleen C.
Acta Medica Philippina 2016;50(2):104-109
The survival rate and prognosis for neonates with airway obstruction is poor if not managed immediately after delivery. Ex utero intrapartum treatment (EXIT) is indicated for cases in which airway obstruction is anticipated. The procedure establishes the fetal airway prior to complete delivery while maintaining an intact uteroplacental circulation. Maintaining uteroplacental circulation, ensuring uterine relaxation, and temporizing placental detachment during the EXIT procedure are achieved by administering a higher dose of inhalation anesthetic and intravenous nitroglycerine. However, this can lead to maternal hypotension and compromised feto-placental perfusion, reduced fatal cardiac output and acidosis. It is therefore essential that these be managed using vasopressors and inotropes. This paper reports the first institutional experience with the EXIT procedure in the Philippines, presenting two cases of neonates with large cystic hygroma. One case was performed as an elective procedure, the other as emergency treatment.
Human ; Female ; Adult ; Acidosis ; Airway Obstruction ; Anesthetics, Inhalation ; Cardiac Output ; Emergency Treatment ; Fetus ; Hypotension ; Infant, Newborn ; Lymphangioma, Cystic ; Philippines ; Placental Circulation ; Pregnancy ; Prognosis ; Survival Rate
6.Successful management of uterine arteriovenous malformation by laparoscopic bilateral uterine artery ligation.
Matundan Katherine R. ; Nano Nerissa Gracia G. ; Tan Cardoso German C.
Philippine Journal of Obstetrics and Gynecology 2016;40(4):29-33
Arteriovenous Malformations are vascular disorders where there is an abnormal communication between an artery and vein. It can occur anywhere in the body not even sparing the uterus. Uterine Arteriovenous Malformations (AV Malformation) is a rare occurrence with less than 100 cases reported in literature. It can cause significant bleeding leading to anemia and even hypovolemic shock. It may be acquired from previous uterine manipulation such as dilatation and curettage and previous uterine surgeries. Diagnosis is made by angiography or doppler ultrasonography. Definitive treatment is hysterectomy however a less invasive, fertility preserving are uterine vascular occlusion techniques, of which the treatment of choice is Uterine Artery Embolization (UAE). We present our experience with 24 year-old G2P2 (1101) with scarred uterus suffering from recurrent profuse vaginal bleeding suspected to have uterine arteriovenous malformation. Laparoscopic bilateral uterine artery ligation, an alternative, more economical, relatively safe and available treatment option was given to the patient.
Human ; Female ; Adult ; Uterine Artery Embolization ; Arteries ; Veins ; Patients ; Curettage ; Dilatation ; Diagnosis ; Angiography ; Ultrasonography, Doppler ; Hysterectomy
7.Accuracy of fine needle aspiration cytology and frozen section histopathology for lesions of the major salivary glands.
Lincoln G L TAN ; Mark L C KHOO
Annals of the Academy of Medicine, Singapore 2006;35(4):242-248
INTRODUCTIONIdentifying malignancy either preoperatively or intraoperatively can have a significant impact on the management of salivary gland tumours. We review our experience with fine needle aspiration cytology (FNAC) and frozen section (FS) for salivary gland lesions. We analyse the accuracy of both modalities and their influence on management.
MATERIALS AND METHODSRetrospective review of 114 patients who underwent salivary gland surgery, 91 with intraoperative FS and 68 with preoperative FNAC. Both sets of results were compared against each other and the final histopathological diagnosis.
RESULTSThe accuracy of FS was 92.3%, with a sensitivity and specificity of 62.5% and 100%. Histologic concordance was 92.4% for benign lesions, and 100% for malignant tumours. The accuracy of FNAC was 89.7%, with a sensitivity and specificity of 100%. The non-diagnostic rate was 10.3%. Histologic concordance for FNAC was inferior to that for FS, with only 64.2% of benign lesions and 50% of malignant tumours correctly identified. FNAC did not alter the management of benign disease even when a correct diagnosis was obtained.
CONCLUSIONOur results suggest that FNAC and FS are complementary in usefulness for malignant tumours. However, FNAC does not influence the management of benign lesions and routine FNAC for every patient may not be cost-effective.
Biopsy, Fine-Needle ; standards ; Frozen Sections ; Humans ; Intraoperative Care ; Retrospective Studies ; Salivary Gland Neoplasms ; diagnosis ; pathology ; Salivary Glands ; pathology ; Sensitivity and Specificity ; Specimen Handling
9.Idiopathic intracranial hypertension, empty sella turcica and polycystic ovary syndrome--a case report.
K G Au EONG ; S HARIHARAN ; E C CHUA ; S LEONG ; M C WONG ; P S TSENG ; V S YONG
Singapore medical journal 1997;38(3):129-130
Permanent visual loss is a well established major sequela of idiopathic intracranial hypertension (IIH). It is often insidious and frequently unnoticed by patients with IIH. It is vital to monitor these patients with serial perimetric and visual acuity tests because visual loss can be halted and occasionally reversed if treatment is begun early. We report a case of IIH with an empty sella turcica and polycystic ovary syndrome who developed visual field loss over ten years. This report illustrates the importance of close ophthalmic monitoring and detailed neurological and endocrinological evaluation to prevent complications in such patients.
Adult
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Chronic Disease
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Empty Sella Syndrome
;
complications
;
diagnosis
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Female
;
Humans
;
Polycystic Ovary Syndrome
;
complications
;
diagnosis
;
Pseudotumor Cerebri
;
complications
;
diagnosis
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Vision Disorders
;
diagnosis
;
etiology
10.Clinics in diagnostic imaging (139). Displaced medial meniscus bucket-handle tear.
Wei Yang LIM ; Nor Azam MAHMUD ; Wilfred C G PEH
Singapore medical journal 2012;53(4):283-quiz 288
A 58-year-old man presented with knee pain and swelling, following a previous injury. A displaced bucket-handle tear of the medial meniscus was diagnosed on magnetic resonance (MR) imaging and subsequently confirmed by arthroscopy. MR imaging is accurate in diagnosing bucket-handle tears. The different MR imaging signs of bucket-handle tears include the double posterior cruciate ligament sign, displaced fragment in intercondylar notch sign, absent bow-tie sign, anterior flipped meniscus sign and coronal truncation sign. Specificity is increased when a combination of the different imaging signs is present. Understanding the meniscal anatomy and potential mimics of the bucket-handle tear is important in order to ensure an accurate diagnosis and appropriate management.
Humans
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Knee Injuries
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diagnosis
;
Knee Joint
;
pathology
;
Magnetic Resonance Imaging
;
Male
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Menisci, Tibial
;
pathology
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Middle Aged
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Tibial Meniscus Injuries