1.The influence of pre-infarction angina on ventricular function and prognosis of first acute myocardial infarction in old people
Wei ZHAO ; Yunyun QI ; Fuzhen OUYANG
Chinese Journal of Interventional Cardiology 2001;9(2):67-69
Objective To observe the influence of pre-infarction angina on ventricular function and prognosis of first acute myocardial infarction in old people. Methods 76 first acute myocardial infarction old patients was divided into two groups: angina pectoris group (n=42); no angina pectoris group (n=34). Global left ventricular function was assessed by echocardiography, arrhythmia, cardiogenic shock, heart failure, post-infarction angina and mortality was observed in hospital. Results The rate of cardiogenic shock and heart failure and mortality was lower in angina pectoris group (33.3% vs 58.8%; 2.4% vs 23.5%), LVEF and E/A was higher in angina pectoris group (0.52±0.056 vs 0.45±0.03,0.86±0.29 vs 0.54±0.35), P<0.05. Conclusion pre-infarction angina possesses the protecting effects on ventricular function of first acute myocardial infarction in old people, and can improve the prognosis of first acute myocardial infarction in old people.
2.Interventional treatment for hemorrhage following hepatic biliary and pancreatic surgery
Jiasheng HUANG ; Fuzhen QI ; Jinsheng WU ; Xuan WANG ; Wei CHEN
Chinese Journal of General Practitioners 2012;11(5):362-364
Interventional management was performed in 10 patients with hemorrhage following hepatic biliary and pancreatic surgery.The super-selection arterial embolization was performed in 9 patients using gelfoam pledgets (n =6 ) or metal coils (n =3 ),the procedure was combined with local infusion of reptilase; 1 case was managed by local infusion of reptilase alone.Selective angiography revealed the pseudoaneurysm in 3 cases,contrast media extravasation in 6 cases; in 1 case no obvious bleeding site was found The interventional treatment was successful and hemorrhage stopped in all patients,including one case with reptilase alone with a successful rate of 10/10.The results indicate that interventional treatment is a safe and effective method for hemorrhage following hepatic biliary and pancreatic surgery.
3.Protective effect of selenium on damaged PC12 cells induced by microwave irradiation
Qianfen GONG ; Xuesen YANG ; Guangbin ZHANG ; Fuzhen WEI ; Zhengpin YU
Journal of Third Military Medical University 2003;0(24):-
Objective To observe the damaging effect of microwave on neurons and the protective effect of selenium on damaged neurons after exposure to microwave. Methods In vitro cultured PC12 cells were exposed to 65 mW/cm 2 microwave. The survival rate, SOD activity, GSH-Px activity, and MDA concentration of PC12 cells were detected. The effects of selenium on PC12 cells after exposure to microwave were reflected by these markers. Results Survival rate, activity of superoxide dismutase (SOD), and glutathione peroxidase (GSH-Px) activity of PC12 cells decreased, but malondialdehyde (MDA) concentration of PC12 cells increased after microwave radiation. These changes weakened when PC12 cells were exposed to microwave after pretreatment with selenium. This effect was more significant after pretreatment with selenium at the high dose. Conclusion PC12 cells can be damaged by microwave through peroxidation. Selenium pretreatment can promote the antioxidation and protect PC12 cells from damages induced by microwave.
4.A case report of primary renal fibrosarcoma
Liang LIU ; Helong XIAO ; Shoubin LI ; Yufeng QI ; Junjiang LIU ; Tao YANG ; Liuxiong GUO ; Shouyi GU ; Gang WANG ; Dong WEI ; Fuzhen SUN
Chinese Journal of Urology 2021;42(2):149-150
A patient with intermittent right lumbar pain for more than one month and aggravating for one week was reported. The right laparoscopic radical nephrectomy was performed, and fibrosarcoma of the right kidney was diagnosed. The patient refused further radiotherapy or chemotherapy and was discharged on the 11th after surgery. One year after operation, the patient underwent chest CT, and subdural tumor of right lobe of liver was detected. A surgery was performed in another hospital, and liver metastasis from right renal fibrosarcoma was diagnosed. He was alive four months after operation.
5.A case report of renal leiomyoma with concurred eosinophilic adenoma
Helong XIAO ; Junjiang LIU ; Ting WANG ; Bo GAO ; Gang WANG ; Shouyi GU ; Dong WEI ; Fuzhen SUN ; Tao YANG ; Shoubin LI
Chinese Journal of Urology 2022;43(4):296-298
A female patient who was admitted to the hospital on March 4, 2020 due to the right kidney mass for 4 days by physical examination. Ultrasound examination revealed a single space-occupying lesion in the right kidney, and further examination of the abdominal enhanced CT and three-dimensional reconstruction showed two lesions in the right kidney. The retroperitoneal laparoscopic partial nephrectomy was carried out. The pathological diagnosis were renal leiomyoma and renal eosinophiloma, respectively. After 1 year follow-up, no recurrence or metastasis was found.
6.Comparison of antibody persistence after primary immunization with 5 μg and 10 μg recombinant hepatitis B vaccine among newborns with normal and high response: a five-year following-up
Li ZHANG ; Wei ZHANG ; Jingjing LYU ; Jijuan ZHANG ; Jiaye LIU ; Bingyu YAN ; Yi FENG ; Xiaofeng LIANG ; Fuqiang CUI ; Fuzhen WANG ; Guomin ZHANG ; Aiqiang XU
Chinese Journal of Epidemiology 2017;38(9):1156-1160
Objective To compare the antibody persistence 5 years after primary immunization with 5 μg and 10 μg recombinant hepatitis B vaccine (HepB) among newborns with normal and high response.Methods Newborns who completed three doses of 5 μ g HepB made by recombinant dexyribonucleic acid technique in Saccharomyces (HepB-SC) or 10 μg HepB made by recombinant dexyribonucleic acid technique in Hansenula polymorpha (HepB-HP) were recruited.Standardized questionnaire was used and blood samples were collected 1-6 months (T0) and five years (T1) after the third dose respectively.The titer of anti-HBs was detected by chemiluminescence microparticle imunoassay (CMIA).Those who achieved normal or high antibody response (anti-HBs titer ≥100 mIU/ml) were included in the study and the positive rate (≥ 10 mIU/ml) and titer of anti-HBs at T1 were compared between 5 μg HepB group and 10 μg HepB group.Multivariable analysis was conducted to identify the independent factors associated with the antibody persistence.Results The positive rate of anti-HBs at T1 was 49.92% (943/1 883) and 75.92% (1 135/1 495) respectively in 5 μg HepB group and 10 μg HepB group,the difference was significant (x2=237.75,P<0.001).The anti-IBs geometric mean concentrations at T1 were 10.23 mIU/ml (95%CI:9.38-11.16) and 28.91 mIU/ml (95%CI:26.65-31.35) in the two groups respectively,the difference was also significant (F=280.36,P<0.001).Among those whose anti-HBs titer was < 10 mIU/ml at T1,the distributions of anti-HBs titer were significantly different between 5 μg HepB group and 10 μg HepB group (x2=39.75,P< 0.001).The multivariable analysis showed that dosage of HepB was independently associated with both positive rate and titer of anti-HBs at T1 after excluding the other factors [P<0.001,OR=1.44(95% CI:1.20-1.73);P<0.001,β =0.27 (95% CI:0.14-0.40)].Conclusion Five year anti-HBs persistence after primary immunization with 10 μg HepB might be better than that after primary immunization with 5 μg HepB among infants who achieved normal or high anti-HBs response after primary HepB immunization.
7.Two cases report of segmental testicular infarction
Liang LIU ; Shoubin LI ; Bo GAO ; Junjiang LIU ; Helong XIAO ; Liuxiong GUO ; Shouyi GU ; Gang WANG ; Dong WEI ; Fuzhen SUN ; Tao YANG
Chinese Journal of Urology 2020;41(3):229-230
The segmental testicular infarction rate is extremely low, usually showing acute testicular pain, which needs to be distinguished from testicular tumor, testicular torsion, etc. Only a few cases were reported. In this study, two cases were presented. Case one, a 13-year-old boy, was admitted to hospital due to right testicular swelling and pain for 3 days. Presenting with vomiting once on May 5, 2017.He underwent right scrotum exploration and testicular fixation. Testicular pain was disappeared and discharged on the five days operation. There was no obvious abnormality in color doppler ultrasound after one year after operation. Another patient, a 26-year-old man, was admitted to hospital due to left testicular swelling and pain for 6 on March 15, 2018. He was treated with Xue Saitong, natra heparin calcium and Maizhiling tablets. After seven days of treatment, the testicular pain improved and were discharged. One month after discharge, the patient had no pain or discomfort, and the color Doppler ultrasound showed that the left subtesticular polar-like low-isoecho, and a small amount of star-like blood flow signal around.
8. Sero-epidemiological characteristics of hepatitis E in population aged 1-29 years in China, 2014
Fuzhen WANG ; Xiaojin SUN ; Feng WANG ; Jianhua LIU ; Guomin ZHANG ; Hui ZHENG ; Ning MIAO ; Shuang ZHANG ; Wei ZHANG ; Shengli BI ; Fuqiang CUI ; Liping SHEN ; Xiaofeng LIANG
Chinese Journal of Epidemiology 2019;40(11):1426-1431
Objective:
To analyze the epidemiological characteristics of hepatitis E Virus antibody (anti-HEV) in people aged 1-29 years in China in 2014.
Methods:
Based on database of the national serologic survey of hepatitis B in people aged 1-29 years in China, in 2014, the sample size was estimated. The serum samples of the people surveyed were randomly selected to detect anti-HEV IgG by using enzyme- linked immunosorbent assay (ELISA). Statistical software SAS 9.1.3 was used to calculate the positive rate of anti-HEV and 95