1.Therapeutic Observation of Abdominal Acupuncture plus Moxibustion for Cervical Spondylosis of Vertebral Artery Type
Fuying GONG ; Huan SU ; Jing JIN
Shanghai Journal of Acupuncture and Moxibustion 2015;(11):1085-1087
Objective To observe the clinical efficacy of abdominal acupuncture plus moxibustion in treating cervical spondylosis of vertebral artery type.Method A hundred patients with cervical spondylosis of vertebral artery type were randomized into a treatment group and a control group, 50 cases in each group. The control group was intervened by abdominal acupuncture plus electroacupuncture; while the treatment group was by moxibustion in addition to the treatment given to the control group. After a treatment course, the onset and remission time of vertigo was observed, and the clinical efficacies were compared between the two groups.Result The total effective rate was 96.0% in the treatment group versus 93.8% in the control group, and the difference was statistically significant (P<0.05). There was a significant difference in comparing the onset and remission time of vertigo between the two groups (P<0.05). In comparing the relapse rates 3, 6, and 12 months after the intervention between the two groups, the difference were statistically significant (P<0.01).Conclusion Abdominal acupuncture plus moxibustion is an effective approach in treating cervical spondylosis of vertebral artery type.
2.Relaxation Therapy for the Injured and Disabled Patients after Earthquake
Songhuai LIU ; Zhifeng LIANG ; Fuying JIN ; Changfeng QI ; Layan ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2008;14(7):677-679
The relaxation therapy is a common method in the psychological rehabilitation in the injured and disabled patients,which can release the negative emotions,improve the quality of sleep,decrease the pain of the injured and disabled parts of the body and build up the confidence of life of the patients after the earthquake.After the long-term practice of the psychological rehabilitation in the injured and disabled patients and the experience of the psychological rehabilitation in the injured and disabled patients after the 5·12 Earthquake,the author thinks during the relaxation training psychotherapy of the injured and disabled patients after the earthquake,the choice of technique and procedure of the relaxation therapy should depend on the specific situation of the patients.The author introduces a idiographic method of the relaxation therapy and some suggestions of the implied treatment after the relaxation which is suitable for the injured and disabled patients.
3.Predictive efficacy of miR-27b-3p combined with miR-215 in the recurrence of early gastric cancer after endoscopic submucosal dissection
Jin LI ; Fuying ZHU ; Ya XU ; Yuntong LAN
Journal of Clinical Surgery 2024;32(8):830-834
Objective To investigate the efficacy of micrornas(miR)-27B-3P combined with miR-215 in predicting the recurrence of early gastric cancer after endoscopic submucosal dissection(ESD).Methods A total of 122 patients with early gastric cancer admitted to the hospital from January 2021 to February 2022 were selected.All patients received ESD surgery and were followed up for 10~15 months,average(12.57±1.83)months.Patients with early gastric cancer were divided into recurrence group and non-recurrence group according to whether they had recurrence after ESD surgery.The relative expression levels of miR-27b-3p and miR-215 and clinical data of the two groups were compared to analyze the factors affecting the recurrence of early gastric cancer patients after ESD surgery,and analyze the relative expression levels of miR-27b-3p and miR-215 and the predictive value of their combination for the recurrence of early gastric cancer patients after ESD surgery.Results After 10~15 months,average(12.57±1.83)months of follow-up,3 cases of 122 patients were lost to follow-up,the follow-up rate was 97.54%,of which 12 cases relapsed,and the remaining 107 cases did not relapse.The miR-27b-3p in the relapsed group was lower than that in the non-relapsed group(P<0.05),and the relative expression of miR-215 in the relapsed group was higher than that in the non-relapsed group(P<0.05).The proportion of patients with lesion size ≥3 cm and infiltration depth of SM2-SM3 in recurrence group was higher than that in non-recurrence group(P<0.05),and the proportion of patients with R0 resection in recurrence group was lower than that in non-recurrence group(P<0.05).Logistic multivariate regression analysis showed that the lesion size was ≥3 cm and the depth of invasion was SM2-SM3,the relative expression level of miR-27b-3p,the relative expression level of miR-215 were the influential factors for recurrence of early gastric cancer patients after ESD operation(P<0.05).The relative expression levels of miR-27b-3p and miR-215 and their combined prediction of the area under the curve(AUC)of ESD postoperative recurrence in early gastric cancer patients were 0.783,0.845 and 0.935,respectively.Conclusion miR-27b-3p and miR-215 can be used to predict the recurrence risk of early gastric cancer patients after ESD surgery,and the combination of Mir-27B-3P and Mir-215 has higher predictive value.
4.Effect of Anshen Navel Plaster on Spontaneous Activities And Levels of GABA, 5-HT in Insomnia Rats Caused by PCPA
Fuying JIAO ; Guoxin LI ; Jin MA ; Zhaoqing MU ; Yu GAN ; Min QIAO ; Tie QIAO
World Science and Technology-Modernization of Traditional Chinese Medicine 2017;19(12):2012-2016
This experiment was aimed to mainly observe the effect of Anshen navel plaster on autonomic activities and to compare neurotransmitter gamma-aminobutyric acid (GABA) and monoamine neurotransmitter (5-HT) contents change of insomnia rats.The rats were treated by P-chlorophenylalanine (PCPA),which can make healthy rats lose sleep.The rat model of insomnia was prepared by intraperitoneal injection of PCPA.The healthy SD rats were randomly divided into the blank control group,model control group,low dosage of Anshen navel plaster group,high dosage of Anshen navel plaster group and Tongren Anshen pill group according to the random number table.EthoVision were used to record the rat's autonomic activities.Content changes of 5-HT and GABA of rats in each group were measured by enzyme-linked immunosorbent assay (ELISA).The results showed that rat's autonomic activities were decreased in the Anshen navel plaster group and Tongren Anshen pill group,which indicated that the Anshen navel plaster had a good sedative effect.Intraperitoneal injection of PCPA can remarkably change rat's serum neurotransmitter expression levels,especially GABA and 5-HT.After the intervention of experimental drugs,compared with the model group,the expression levels of GABA and 5-HT were increased significantly.It was concluded that Anshen navel plaster has obvious sedative effect.It can regulate the contents of sleep factors such as GABA and 5-HT.