1.Mongolian Traditional Medicine and Medicinal Plants.
Fumihide TAKANO ; Fumihiko YOSHIZAKI ; Shinji FUSHIYA ; Hideki HAYASAKA ; Keiji OHBA ; Javzan Batkhuu ; Chinbat Sanchir ; Badamjav Boldsaikhan
Kampo Medicine 2003;54(5):963-972
We visited Mongolia in the summer of 1999 and again in the summer of 2000, and investigated the traditional and natural medicines of this country. Mongolian traditional medicine is classified into seven categories, namely, massage, acupuncture, herbal medicine, dietary cures, aromatherapy, phlebotomy and sutra recitation. Herbal medicines, as well as acupuncture and massage, are the principal remedies. These remedies are based on Tibetan traditional medicine, which is derived from Indian traditional medicine. In both rural and urban areas, the Mongolian people use many herbs and herbal prescriptions to prevent and cure acute or chronic diseases. Important herbal plant sources, such as the Ephedra and Glycyrrhiza species, are abundant. Since the abandonment of socialism, traditional medicine has made a rapid comeback and is now a popular and important remedy in Mongolia.
2.Oral Administration of the Potato Peel Extract Affects Cytokine Production in Murine Peyer’s Patch Cells
Mari SUTO ; Suguru KATO ; Megumi IRISAWA ; Megumi ICHISAWA ; Katsuyuki ISHIHARA ; Rui SAKUMA ; Shinji FUSHIYA ; Fumihide TAKANO
Japanese Journal of Complementary and Alternative Medicine 2014;11(2):107-110
We investigated the effects of an ethanol extract of potato peel on T helper cytokines production in cultured murine Peyer’s patch cells ex vivo. Oral administration of the 70% ethanol extract at 100 mg/kg/day significantly enhanced the production of the Th1 cytokine IL-2 in response to concanavalin A. A decrease in the production of the Th2 cytokine IL-4 and the Th17 cytokine IL-17 was observed. The production of the Treg cytokine IL-10 was not affected. These results suggest that the potato peel extract stimulates Th1 immune response.
3.Acute Oral Toxicity Test of Hot Water Extract of Coix lacryma-jobi L. var. ma-yuen Stapf in Rats
Hirotaka HAYASHI ; Yasuyuki OHTA ; Takanari ARAI ; Yasuko SHIMANO ; Fumihide TAKANO ; Jeffry Michael STRONG ; Toshiki ENOMOTO ; Kazuo UEBABA ; Tomihisa OHTA ; Nobutaka SUZUKI
Japanese Journal of Complementary and Alternative Medicine 2009;6(2):105-110
Coix lacryma-jobi L. var.ma-yuen Stapf (Coix seed) is a grass crop that has long been used in traditional medicine as a nourishing food. However, high-intake safety of the extract of the husks, pellicles and astringent skin of Coix seed has rarely been evaluated. We performed a safety test of hot water extract of all parts of Coix seed (CRD extract) in rats. CRD extract showed no significant toxicity on body weight, blood analyses, urinalysis and histopathological examination in acute toxicity tests.
4.Study of Inhibitory Effect of Polyphenols from Fragaria ananassa on Fat Accumulation in Rat White Adipocyte
Tetsuro ABE ; Saki YOSHIDA ; Tetsuro KAWABATA ; Fumihide TAKANO ; Tomihisa OHTA
Japanese Journal of Complementary and Alternative Medicine 2018;15(1):1-7
On the study of polyphenols from Fragaria ananassa fruit, we reported that some polyphenols showed inhibition of metabolic enzyme, cytochrome P450. Continuous study of health effects of F. ananassa fruit, we isolated a new quercetin glycoside, flagarin, quercetin-3-O- β-glucuronyl- (2→1)- β-D-xyloside along with ten known compounds. Those compounds showed inhibitory activity of fat accumulation in rat white adipocyte. Among the isolated compounds, strictinin and the new compound, flagarin showed high inhibitory activity of fat accumulation in rat white adipocyte.