The purpose of this study is to investagate the meaning of systolic time intervals (STI) in evaluating cardiac functional condition of athletes.1. STI and step test were examined on 13 sprinters, 8 jumpers, 5 throwers and 5 distance runners during early, middle and the last phases in summer training season.No significant changes of the left ventricular ejection time (LVET), the pre-ejection period (PEP) and PEP/LVET ratio were found from examinations on athletes in the three different phases.The cases were divided into two groups of PEP/LVET ratio increased more than 0.05 (N=8) and PEP/LVET ratio decreased more than 0.05 (N=10) by the different of PEP/LVET ratio between linked phases examinations. Athough two of PEP/LVET ratio of each group were different evidently (P

In this study, the cardiac structure and function in 102 athletes with high voltage of left ventricle inECG were examined by echocardiogtaphy, apexcardiography, systolic time intervals, X-ray cardiac measure-ment and physical work capacity tests. The parameters obtained were compared with those of 110 athletes withnormal voltage of left ventricle. Results showed no significant difference between these two groups either in cardiac structure (LYID,PWT, IYST) or in catdiac function (STI's, SV, EF, Vcf, PWV). The results of this study may be ofpractical value to the work of medical supervision and physical training.

Apexcardiogram (ACG) was applied clinically to evaluation of hemodynamics and cardiac functicn. especially diastolic function. So far no information in this field is available. 193 athletes engaged in different types of training --- including 118 males with an average age of 22.4 and training period of 4.5 years and 75 females with an average age of 21.4 years and training period of 5.2 years --- were examined with ACG in left lateral decubitus position. A/H ratio, rapid filling wave (RFW), slow filling wave (SFW) and SFW/RFW ratio were calculated.1. The sex difference was significant in RFW (P

Objective: To discuss the entry point of clinical pharmacists for providing pharmaceutical care in clinics. Methods:Clinical pharmacists participated in making drug treatment regimen for one child with nephritic type NS combined with hypertension,and provide pharmaceutical care and medical education for the patient. Results: According to the situation of the patient, the treatment regimen was made out, evaluated and adjusted, and ADR was dealt with in time, therefore, the individualized treatment showed obvious effect, and the child was discharged with an improved condition. Conclusion: Clinical pharmacists can participate in clinical treatment with pharmaceutical professional knowledge to ensure safer and more effective drug use in child patients.

Objective:To explore the possibility of repairing partial nasal alar defects with individualized design of localized skin flaps.Methods:The clinical data of 38 patients with nasal alar region tumor from October 2015 to June 2019 in Dalian Municipal Central Hospital were retrospectively analyzed, including 5 cases with intradermal nevus, 8 cases with junction nevus, 21 cases with basal cell carcinoma, 3 cases with trichoepithelioma, and 1 case with nasal alar sulcus fistula combined with infection. Surgical treatment with local anaesthesia was applied, and intraoperative freezing pathology was used to confirm the diagnosis and determine the safe margin. There was no nasal alar cartilage infiltration in all patients. The defect areas after resection of nasal alar lesions ranged from 1.0 cm × 1.0 cm to 3.0 cm × 2.5 cm. Local skin flap was aesthetically designed in accordance with the location and size of the nasal alar defect to primarily repair the defect. Among them, 15 cases were repaired with pedicled nasolabial groove flap, 10 cases with modified rhomboid flap, 6 cases with rotatory nasolabial groove flap, 5 cases with V-Y push flap, and 2 cases with double lobe flap.Results:One case had blood transportation obstacle after operation caused by compression and bandaging, 1 case had postoperative infection. Healing of the two cases delayed after treatment, and other patients healed properly. All the flaps survived without facial deformity, and the cosmetic effect was good.Conclusions:The primary repair of the nasal alar defect needs to follow the aesthetic requirements of the nose and face, which varies with diseases and experience of doctors. Flap selection should be individualized to achieve both the purpose of repairing defects and beauty.

In order to determine the pathophysiologic significance of electrocardiographic ventricular hypertrophy in athletes (LVH ath), echocardiographic measurements of left ventricular mass (LVM) were performed on 50 LVH ath. and 50 non-LVH matched ath. They were members of National Teams of track and field, swimming, football and cycling, with an average age of 20.74?3.3 years. Anatomic validation of the method was used for calculation of LVM in this study. Comparisons of LVM were made between LVH ath. and non-LVH ath., and between non-LVH ath. and the untrained:LVM=1.04?[(LVID+PWT+IVST)~3-(LVID)~3]-14Results showed no significant difference of LVM between LVH ath. and non-LVH ath. while LVM of non-LVH ath. were considerably greater than that of the untrained (P

Objective:To investigate the effect of chronic alcohol consumption on both left ventricular myocardial collagen and diastolic function in rats,and their relationship thereof.Methods:Twenty-four male Wistar rats were randomly divided into 2 groups:control group(n=12)and ethanol group(n=12).The changes in cardiac diastolic function were evaluated by echocardiography and tissue Doppler imaging(TDI).The value of myocardial hydroxyproline content was determined by hydroxyproline reagent kit.The expressions of collagen Ⅰ and collagen Ⅲ mRNA were detected by RT-PCR analysis.Results:It was found that mitral E and mitral annulus Ea were decreased,mitral annulus Aa was increased,and isovolumic relaxation time(IVRT)was prolonged in the ethanol group compared with those in control group(P＜0.05).The value of Ea/Aa ratio was greater than 1 in control group and less than 1 in ethanol group(P＜0.01).It was found that myocardial hydroxyproline content,collagen Ⅰ,collagen Ⅲ mRNA expression and their ratio significantly increased in ethanol group compared with those in the control group(P＜0.01).There was positive correlation between hydroxyproline content,collagen Ⅰ,collagen Ⅲ mRNA expression,and collagen Ⅰ /collagen Ⅲ mRNA ratio with IVRT(P＜0.05),and negative correlation between hydroxyproline content,collagen Ⅰ,collagen Ⅲ mRNA expression,and collagen Ⅰ /collagen Ⅲ mRNA ratio with the Ea/Aa ratio(P＜0.01).Conclusion:Chronic ethanol consumption can induce increase in left ventricular myocardial collagen synthesis and impairment in diastolic function in rats.Left ventricular diastolic dysfunction correlates with increase in myocardial collagen synthesis positively.

Objective To explore the value of high-resolution MRI in in the preoperative evaluation of children with type Ⅰ focal cortical dysplasia (FCD). Methods The MRI and related clinical data of 52 children with FCD Ⅰ confirmed by pathology were retrospectively analyzed,Compare the detection rates of major MRI signs of type Ⅰ FCD (focal demarcation of gray and white matter,focal cortical structure abnormalities,abnormal white matter signal lesions,and local atrophy / hypoplasia) of high-resolution imaging and conventional MRI sequences,and comparisons in the assessment of lesion extent,borders,and completeness were perfomed. Results The detection rate of high-resolution imaging for blurring of gray-white matter boundaries,focal cortical structural abnormalities,and abnormal white matter abnormalities was higher than that of conventional sequences (P<0.05),there was no significant difference in the detection rate of local atrophy/dysplasia (P>0.05). 3D-T1WI showed the range and boundary of the lesion better than the conventional T1WI sequence,3D-T2FLAIR was more complete than the conventional T2FLAIR sequence. Conclusion The high-resolution MRI could improve the detection rate of various major signs of type Ⅰ FCD,could more fully display the lesion and accurately assess the scope and boundary of the lesion,and was the preferred MRI imaging sequence before surgery.