1.Investigation on Mobile Phone Based Thermal Imaging System and Its Preliminary Application.
Fufeng LI ; Feng CHEN ; Jing LIU
Chinese Journal of Medical Instrumentation 2015;39(3):173-176
The technical structure of a low-cost thermal imaging system (TIM) lunched on a mobile phone was investigated, which consists of a thermal infrared module and mobile phone and application software. The designing strategies and technical factors toward realizing various TIM array performances are interpreted, including sensor cost and Noise Equivalent Temperature Difference (NETD). In the software algorithm, a mechanism for scene-change detection was implemented to optimize the efficiency of non-uniformity correction (NUC). The performance experiments and analysis indicate that the NETD of the system can be smaller than 150 mK when the integration time is larger than 16 frames. Furthermore, a practical application for human temperature monitoring during physical exercise is proposed and interpreted. The measurement results support the feasibility and facility of the system in the medical application.
Algorithms
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Body Temperature
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Cell Phone
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Humans
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Infrared Rays
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Mobile Applications
2.Auricular application press fit of dietary intervention in the treatment of perimenopausal syndrome
Zhihong YU ; Xiufang CAO ; Weihong LIU ; Fufeng LIU
Chinese Journal of Primary Medicine and Pharmacy 2016;23(3):364-367
Objective To explore the auricular application pressure added dietary intervention of perimeno-pausal syndrome (PS)the influence of women's sex hormone levels.Methods Research subjects were randomly divided into two groups.The observation group was given auricular application pressure to add dietary intervention, control group was given dietary intervention alone.Before and after six months of follow -up,sex hormone levels in the blood were monitored.Results After the intervention,the estrogen level of the observation group was (272.93 ± 15.71)pmol/L,progesterone was (3.14 ±0.47)nmol/L,which of the control group was (186.32 ±12.80)pmol/L, (2.86 ±0.34)nmol/L;After the intervention,the follicular thorn hormone content of the two groups were decreased, which of the observation group was (12.88 ±1.50)U /L,which of the control group was (21.35 ±4.70)U /L;The perimenopausal symptoms were reduced,Kuppermun score in the observation group were (9.36 ±1.41 )points, (10.43 ±1.63)points,the difference between the two groups were statistically significant (t =40.15,4.52,3.82, 4.65,all P <0.01)for the control group.Conclusion Auricular application press fit dietary intervention for patients with perimenopausal syndrome sex hormone regulation of metabolic disorders has obvious effect,can significantly improve the patients'symptoms of the menopausal transition,it is worthy of further research on intervention measures.
3.Feature extraction and recognition of traditional Chinese medicine pulse based on hemodynamic principles.
Rui GUO ; Yiqing WANG ; Haixia YAN ; Fufeng LI ; Jianjun YAN ; Zhaoxia XU ; Guoping LIU
Journal of Integrative Medicine 2010;8(8):742-6
Abstract: In this paper, factors contributing to the formation of pulse wave were analyzed based on hemodynamic principles. It is considered that formation of pulse wave was related to its propagation and reflection characteristics. Propagation of the pulse wave was characterized by pulse wave velocity, and reflection of the pulse wave was characterized by reflection coefficient. Pulse wave velocity and reflection coefficient were proposed as the eigenvectors of pulse wave in pulse diagnosis of traditional Chinese medicine, and support vector machine (SVM) was used to recognize slippery pulse, stringy pulse and plain pulse. Pulse wave velocity and reflection coefficient of the slippery, stringy and plain pulses in healthy people were calculated in this study, and SVM with Gaussian radial basis function was used for classifying. Results showed that pulse wave velocity and reflection coefficient with physiological and pathological significance had advantages in distinguishing slippery pulse, stringy pulse and plain pulse, which offered a new idea for recognizing pulse condition.
4.Visualized Analysis of Tongue and Face Diagnosis Image Feature Extraction,Segmentation and Classification Based on Complex Network
Huilin LIU ; Ji HAN ; Fufeng LI
World Science and Technology-Modernization of Traditional Chinese Medicine 2024;26(5):1336-1343
Objective To summarize and analyze relevant literature on image feature extraction,segmentation,and classification of tongue and facial diagnosis,we explore the research hotspots and development trends in this field and provide ideas for future research on image processing of tongue and facial diagnosis.Methods China National Knowledge Infrastructure was used as the data source,and 439 papers were included according to the exclusion criteria,the inclusion criteria,and the search strategy.Finally,Gephi software was applied to visualize and analyze the co-word network of authors,research institutions,and keywords of relevant literature.Results The overall number of articles issued is low as seen in the annual volume,but the overall trend is steadily increasing.The research team is mainly represented by the team of Li Fufeng,Zhang Xinfeng,Xu Jiatuo,Wang Yiqin,and Wang Hongwu.Most of the research institutes are regional medical-industrial crossover collaborations.Conclusion Hot research trends gradually toward deep learning for image processing.Meanwhile,teamwork across regions and institutions needs to be strengthened.It is recommended to further promote the development of multidisciplinary cross-fertilization and intelligent and objective quantification of Traditional Chinese Medicine diagnosis(tongue and face diagnosis).
5.Development and evaluation of an inquiry scale for diagnosis of heart system syndromes in traditional Chinese medicine.
Guoping LIU ; Yiqin WANG ; Ying DONG ; Naiqing ZHAO ; Zhaoxia XU ; Fufeng LI ; Haixia YAN ; Peng QIAN ; Rui GUO ; Xiaodan ZHANG ; Dan DI
Journal of Integrative Medicine 2009;7(1):20-4
To develop an inquiry scale for diagnosis of heart system syndromes, and to discuss the provisional standardization of the inquiry method in traditional Chinese medicine (TCM).
6.Application of modified indwelling catheterization method for the prevention of urethral injury
Fufeng? LIU ; Zhihong YU ; Lingqiu MA ; Jinmei XU
Chinese Journal of Modern Nursing 2015;21(5):605-606
Objective To study the effect of modified indwelling catheterization method for the prevention of urethral injury. Methods A total of 136 cases of urethral catheterization were randomly divided into two groups. The observation group had 68 cases using the conventional catheterization method, and the control group had 68 cases using the modified indwelling catheterization method, respectively. The time of inserting catheter, indwelling catheter time, removal time of the catheter, and the incidence of blood urine were compared between two groups. Results The time of inserting catheter, indwelling catheter time, removal time of the catheter, and the incidence of blood urine were significantly of the observation group were significantly lower than those of the control group (χ2 =6. 81,3. 89,8. 38,28. 57, respectively; P<0. 05). The incidence of leakage of urine had no significant difference (P>0. 05). Conclusions The modified indwelling catheterization method can reduce the occurrence of hematuria traumatic urethral and it is worthy of application in clinical environment.
7.Engineering the plastic degradation enzyme Ple629 from marine consortium to improve its thermal stability.
Yipei ZHAO ; Hao WANG ; Pan WU ; Zhishuai LI ; Fufeng LIU ; Qun GU ; Weidong LIU ; Jian GAO ; Xu HAN
Chinese Journal of Biotechnology 2023;39(5):2040-2052
Petrochemical-derived polyester plastics such as polyethylene terephthalate (PET) and polybutylene adipate terephthalate (PBAT) have been widely used. However, the difficulty to be degraded in nature (PET) or the long biodegradation cycle (PBAT) resulted in serious environmental pollution. In this connection, treating these plastic wastes properly becomes one of the challenges of environment protection. From the perspective of circular economy, biologically depolymerizing the waste of polyester plastics and reusing the depolymerized products is one of the most promising directions. Recent years have seen many reports on polyester plastics degrading organisms and enzymes. Highly efficient degrading enzymes, especially those with better thermal stability, will be conducive to their application. The mesophilic plastic-degrading enzyme Ple629 from the marine microbial metagenome is capable of degrading PET and PBAT at room temperature, but it cannot tolerate high temperature, which hampers its potential application. On the basis of the three-dimensional structure of Ple629 obtained from our previous study, we identified some sites which might be important for its thermal stability by structural comparison and mutation energy analysis. We carried out transformation design, and performed expression, purification and thermal stability determination of the mutants. The melting temperature (Tm) values of mutants V80C and D226C/S281C were increased by 5.2 ℃ and 6.9 ℃, respectively, and the activity of mutant D226C/S281C was also increased by 1.5 times compared with that of the wild-type enzyme. These results provide useful information for future engineering and application of Ple629 in polyester plastic degradation.
Plastics/metabolism*
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Polyethylene Terephthalates/metabolism*
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Biodegradation, Environmental
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Metagenome