1.Comparability research on blood glucose results among different kinds of detection systems
Fudong LUO ; Xianzhang HUANG ; Junhua ZHUANG
International Journal of Laboratory Medicine 2006;0(02):-
Objective To discuss the comparability of blood glucose(Glu)results with different detection systems.Methods Six different kinds of biochemistry detection systems were used to detect plasma Glu concentrations at 2 levels of Randox quality controls and 48 clinical plasma according to EP9-A file.The collected data were treated with statistical analysis.Results Analysis of variance showed Glu results from different control and patients plasma had significant difference between various detection systems (P
2.Clinical evaluation of delayed open reduction and internal fixation with anatomic plate for fracture of distal tibia and fibula
Huizhong ZHANG ; Fudong HUANG ; Xiao LIANG
Chinese Journal of Primary Medicine and Pharmacy 2006;0(05):-
Objective To analyze the results of distal tibia and fibula fracture treated with delayed open reduction and internal fixation with anatomic plate.Methods 24 fracture of distal tibia and fibula were stabilized temporanrily by application of plaster splint or calcaned traction immediately after injury.The definitive internal fixations were performed on an average of 8 days(range 7 to 10 days) after injury as soon as the soft tissue recovered.Results All patients were available for follow-up at an average of 2.6 years(range,1 to 4.5 years) after surgery.All fracture headed at an average of 15.4 weeks(range,12 to 29 weeks) postoperatively.There were 16 excellent,6 good,1 fair,and 1 poor results.The excellent and good rate was 92%.Conclusion This two-stage treatment protocol for fracture of distal tibia and fibula leads to the best long-term outcomes.
3.Comparison of Therapeutic Effects Between Ear Point Seed Embedding Method and Acupuncture in the Treatment of Female Menopause Syndrome
Dongmei SUN ; Qiuhua SHAN ; Fudong WU ; Guoqi HUANG
Journal of Acupuncture and Tuina Science 2004;2(4):29-32
To observe and compare the therapeutic effects of treating female menopausal syndrome with auricular-point-pressing therapy and acupuncture, 86 patients were randomly divided into auricularpoint pressing group and acupuncture group, the comparative observation was conducted according to a modified Kupperman index. Statistical analysis showed that there's no significant difference between the therapeutic effects of the two groups. Auricular-point-pressing therapy and acupuncture were both effective in treating female menopausal syndrome, while auricular-point-pressing had the advantages of easy operation and acceptance.
4.Aerobic exercise modulates changes in cardiac function due to simulated weightlessness through the AMPK/ULK1/Beclin1 pathway
Yequn LIU ; Jianjun YANG ; Min YANG ; Hongli LI ; Fudong GAO ; Yuxuan HUANG ; Shuling ZHANG ; Junzhi SUN
Space Medicine & Medical Engineering 2024;35(4):235-240
Objective To explore the possible mechanisms of myocardial injury induced by simulated weightlessness in space flight and the recovery of myocardium in rats by aerobic exercise intervention.Methods The body weight of rats was weighed using an electronic balance;the cardiac function indexes of rats in each group were detected using echocardiography and isolated cardiac perfusion;and the expression of proteins related to the AMPK/ULK1/Beclin1 pathway in the myocardial tissues of rats in each group was detected using Western Blot.Results(1)When compared with the C1 group,the T1 group not statistically significant in body weight(P?>?0.05),and the wet weight of the flounder muscle,the wet weight-to-weight ratio of the flounder muscle,and the heart weight were all significantly decreased(P?0.01).(2)After 4 weeks of tail suspension and 4 weeks of aerobic exercise,significant changes in cardiac function-related indexes occurred,with a significant increase in the expression levels of AMPK and p-ULK1 in the T1 group(P?0.01),a significant increase in the expression of p-AMPK(P?0.05),and a slight,but not statistically significant,increase in the expression of ULK1 and Beclin1(P?>?0.05).After 4 weeks of aerobic exercise,when compared to group C2,group R showed a significant rise in the expression of AMPK and ULK1(P?0.05),a decrease in the expression of p-AMPK and p-ULK1,but not statistically significant(P?>?0.05),and a rise in the expression of Beclin1,but not statistically significant(P?>?0.05);and group A showed a slight increase in the expression of AMPK,ULK1 and Beclin1 expression decreased slightly but not statistically significant(P?>?0.05),p-AMPK expression decreased significantly(P?0.05)and p-ULK1 expression decreased significantly(P?0.01)in Group A.When compared with group R,group C2 showed a significant decrease in the expression of cardiac protein AMPK(P?0.05),a slight increase in the expression of p-AMPK and p-ULK1,a statistically insignificant decrease in the expression of Beclin1(P?>?0.05),and a significant decrease in the expression of ULK1(P?0.01);and group A showed a significant decrease in the expression of AMPK,ULK1(P?0.01);the expression of p-AMPK and Beclin1 decreased slightly but not statistically significant(P?>?0.05);the expression of p-ULK1 decreased significantly(P?0.05).Conclusion(1)After 4 weeks of tail suspension,it was found that the wet weight,and wet weight to body weight ratio of the flounder muscle of rats were significantly reduced,the weight of the heart and cardiac function related indexes were also significantly reduced,and the expression of AMPK,p-AMPK,ULK1,p-ULK1 and Beclin1 increased;(2)After 4 weeks of aerobic exercise,it was found that the morphology of the myocardium of the rat with tail suspension,the myocardial ultrastructure and cardiac function related indexes increased,and cardiac function was improved.function-related indexes rose,cardiac function was somewhat improved,and the expression of AMPK,p-AMPK,ULK1,p-ULK1,and Beclin1 declined;(3)he damage and improvement of cardiac function were associated with the regulation of related proteins through the AMPK/ULK1/Beclin1 pathway,and the regulation of the expression of AMPK,p-AMPK,ULK1,p-ULK1,and Beclin1.
5.A time-series study on the impact of air pollution on the death of permanent residents in Yancheng City
Liancheng HUANG ; Jie LI ; Fudong LIU ; Yonghong LI ; Quan TANG
Journal of Public Health and Preventive Medicine 2020;32(4):18-22
Objective To investigate the effects of air pollution on non-accidental death of residents in Yancheng City. Methods Data of daily air pollutions (PM2.5, PM10, NO2, SO2 and O3), average temperature, average relative humidity, and daily death information during 2014-2019 were collected. The time series semi parametric generalized additive model was used to analyze the impact of short-term exposure of air pollutants on non-accidental death in Yancheng City. Results The average daily non-accidental deaths of the entire population, respiratory system, and circulatory system were 154, 25, and 51, respectively. With the increase of 10 µg/m3 SO2, the risk of the estimated non-accidental death and respiratory death was increased by 1.19% (95%CI: 0.26%-2.12%) and 2.37% (95%CI: 0.65%-4.12 %), respectively. With the increase of 10 µ g/m3 NO2, the risk of the estimated non-accidental death, circulatory system death and respiratory death was increased by 1.50%(95%CI:0.94%-2.05%), 1.11%(95%CI:0.08%-2.16%), and 1.53%(95%CI:0.71%-2.36%), respectively. With the increase of 10 µg/m3 O3, the risk of the estimated non-accidental death, circulatory system death and respiratory death was increased by 0.64%(95%CI: 0.25%-1.04%), 0.81%(95%CI: 0.04%-1.58%), and 0.78%(95%CI: 0.18%-1.37%), respectively. Conclusion The short-term exposure of air pollutants affects the non-accidental death of the residents in Yancheng, and there are lag effects, of which NO2, SO2 and O3 have a greater impact.