Objective To identify the risk factors for early postoperative cognitive dysfunction (POCD) in the elderly patients undergoing spinal surgery.Methods One hundred and fifty ASA Ⅱ or Ⅲ patients,aged ≥65 yr,undergoing elective spinal surgery under general anesthesia,were studied.Venous blood samples were taken at 1 day before operation and 7 days after operation to determine the concentration of serum S-100B protein.Cognitive function was assessed by Mini-Mental State Examination (MMSE) at 1 day before operation and 7 days after operation.The patients were diagnosed as having POCD if MMSEpre-MMSEpost ≥ 3.The patients were divided into POCD group and non-POCD group.Age,body weight,sex,education,type of operations,complications,preoperative TCM syndrome type,MMSE score at 1 day before operation and 7 days after operation,duration of operation,emergence time,and intraoperative blood loss,cardiovascular events,and amount of fluid infused per hour were recorded.The risk factors for POCD were analyzed using multivariate logistic regression analysis.Results Thirty-eight patients developed early POCD (25.3％).The resuhs of logistic regression analysis showed that age ≥ 70 yr,elementary education or below,duration of operation ≥5 b,and the number of hypotension occurred during operation≥3 were the risk factors for early POCD.Conclusion Age≥70 yr,elementary education or below,duration of operation ≥ 5 h,and the number of hypotension occurred during operation ≥ 3 are the risk factors for early POCD in the elderly patients undergoing spinal surgery.

Objective To observe the efficacy of oral short-acting contraceptives after abortion surgery. Methods A to-tal of 200 cases who were voluntarily requested termination of pregnancy in our hospital were randomly divided into the observation group (100 cases) and the control group (100 cases). Antibiotics and Motherwort particles were given to the control group. Marvelon, antibiotics and Motherwort particles were given to the observation group after abortion. Thera-peutic effect of two groups was observed and compared. Results The observation group postoperative recovery was sig-nificantly better than the control group, the difference was statistically significant (P<0.05). The incidence of adverse reaction was significantly lower than that of the control group, the difference was statistically significant(P<0.05). Con-clusion Oral short-acting contraceptives after abortion surgery not only can promote postoperative recovery, reduce ad-verse reaction, beneficial to the women's physical and mental health.