1.Estimation of interventional radiology worker's effective dose by using three kinds of double-dosimetry algorithms
Qiang WANG ; Qiang FU ; Lin LIN
Chinese Journal of Radiological Medicine and Protection 2016;36(12):935-939
Objective To compare three kinds of double-dosimetry algorithms used in estimating interventional radiology worker's effective dose.Methods TLDs were put in the Alderson Radiation Therapy Phantom (ARTP) dressed with lead apron,lead cap and lead collar.TLDs were put on the front left chest inside the lead apron and on the left outside lead collar,respectively.Radiation scattering models,intensity-modulated radiotherapy body model at one time and CT dose detection model at another time,were put on the operating table.The ARTP was set at the major operator's position exposed to the Xray,mimicking the real interventional radiology operation.Effective doses were estimated on the basis of organ absorbed doses.Effective doses were also obtained by the use of three kinds of double-dosimetry algorithms.The later three effective doses were compared with the first one.Results Two groups of effective doses were obtained,with each including four data.For intensity-modulated radiotherapy body model,effective doses were 0.138 mSv for phantom method,0.097 mSv for NCRP algorithm,0.161 mSv for Niklason's algorithm and 0.173 mSv for Boetticher's algorithm,respectively.For CT dose detection model,effective doses were 0.018,0.013,0.019 and 0.026 mSv,respectively.The result obtained by using the Niklason's algorithm was the closest to that by using phantom method.Conclusions Niklason's algorithm is more accurate and more practical in eatimating interventional radiology worker's effective dose.
2.Factors influencing the quality of life of spouses of spinal cord injury patients
Jinying FU ; Yuanjiao WANG ; Jian LIN
Chinese Journal of Physical Medicine and Rehabilitation 2011;33(10):759-761
Objective To explore quality of life (QOL) of spouses of spinal cord injury patients,as well as its influencing factors.Methods Sixty-eight spouses of spinal cord injury patients were recruited as an observation group.At the same time,another 70 healthy married people who had no serious chronic diseases in the family but were matched in gender,age,occupation and education were chosen as a control group.The QOL of all the subjects in both groups was investigated by way of a questionnaire survey.The results of both groups were compared and factors that influenced their QOL were explored.Results The QOL of spouses of spinal cord injury patients,including total QOL ( 3.22 ± 0.37 ),physiological function ( 60.57 ± 14.22 ),psychological state ( 60.09 ± 8.06 ),social relations (63.37 ± 8.10 ) and the living environment (66.86 ± 11.26 ) were significantly lower than in the control group (4.62 ± 0.75 ; 82.48 ± 10.92 ; 86.02 ± 8.75 ; 85.94 ± 10.13 and 83.23 ± 9.54,respectively).The QOL of spouses of spinal cord injury patients was closely related to the patient's injury type,injury position,the treatment protocol,as well as their own gender,vocation and education.Conclusion The QOL of spouses of spinal cord injury patients is significantly lower than that of normal people,and closely related with the patients' injury type,injury position and treatment,as well as their own gender,vocation and education.
3.Promotion of disequilibrium of cell proliferation and apoptosis of BID as a potential mechanism of IgAN
Lin MA ; Shuxia FU ; Lin YANG ; Jianrong WANG
Basic & Clinical Medicine 2006;0(02):-
Objective To explore the expression of BID protein and the relation ship of cell proliferation with apoptosis at different stages of IgAN.Methods The expression of BID protein、PCNA and FN in renal tissue was detected by immunohistochemistry,TUNEL and light microscopy were used to detect apoptotic cells.Results With the progress of IgAN,the expression of BID protein、PCNA、the number of apoptotic cells and FN increased gradually(P
4.The clinical effect of dexmedetomidine in early psychosis prevention after liver transplantation
Zhi FU ; Xin WANG ; Yuanyuan ZHANG ; Lu WANG ; Dongdong LIN
Chinese Journal of Primary Medicine and Pharmacy 2015;(11):1648-1650
Objective To investigate effects and safety of dexmedetomidine on the prevention of abnormal mental in patients after liver transplantation.Methods 160 patients after liver transplantation were randomly divided into the two groups using the drawing method:midazolam group(n =80),dexmedetomidine group(n =80),compared the two groups of patients with general,mental abnormality and the occurrence of adverse reactions.Results There were no significant differences in the general situation (gender,age,postoperative ventilator time,ICU stay time,oper-ation time,blood FK506 concentration,APACHEII score 24 hours after operation)of the two groups of patients (P >0.05),the spirit of the abnormal rate of the observation group was lower than that of the control group (P =0.009), incidence of hypotension and hypertension in the observation group was higher than that in the control group (P =0.035,0.029).Conclusion Dexmedetomidine can effectively reduce the postoperative mental disorders in patients in the early stage after liver transplantation.
5.The clinical significance of anomalous origination of right gastric artery in interventional treatment for hepatocellular carcinoma
Zhidong LIN ; Chongpei WEN ; Kong FU ; Banghao WANG
Journal of Interventional Radiology 1992;0(01):-
Objective To discuss the clinical significance of anomalous origination of right gastric artery in interventional treatment for hepatocellular carcinoma(HCC).Methods The dynamic enhanced CT scanning of the liver with a 64-slice spiral CT unit was performed in 72 HCC patients.In arterial phase,maximum intensity projection(MIP) and volume reconstruction technique(VRT) were used to observe the origin of the right gastric artery and its relationship with the hepatic artery.The findings were compared with the angiographic results.Results Of the total 72 cases,the anomalous origin of the right gastric artery was found in 43(59.8%).The anomalous origins of the right gastric artery included proper hepatic artery(n=19),left hepatic artery(n=17),gastroduodenal artery(n=4),right hepatic artery(n=2) and common hepatic artery(n=1).The results obtained from three-dimensional reconstruction were in good accordance with angiographic findings.Conclusion The anomalously originated right gastric artery most commonly originates from the left hepatic artery.Three-dimensional reconstruction obtained from the 64-slice spiral CT scans can provide the clear and reliable images of the right gastric artery,which is very helpful for the interventional procedure.
6.Multi-slice spiral CT 3D reconstruction of extrahepatic feeding arteries in hepatocellular carcinoma:its clinical applications
Zhidong LIN ; Chongpei WEN ; Kong FU ; Banghao WANG
Journal of Interventional Radiology 2006;0(08):-
Objective To discuss the feasibility of displaying the extrahepatic feeding arteries in hepatocellular carcinoma with the help of multi-slice spiral CT 3D reconstruction and to assess the clinical value of this technique. Methods Triple-phase enhanced CT scanning with a 64-slice spiral CT scanner was performed in 89 patients with advanced primary hepatocellular carcinoma (HCC). Three-dimensional reconstruction techniques,including maximum intensity projection (MIP) and volume rendering (VR),with arterial phase images,were used to display the origination and course of both the intrahepatic and extrahepatic supplying arteries of HCC. The results were compared with the angiographic findings. Results Of 59 cases with massive type HCC,extrahepatic supplying arteries were found in 33. In 21 cases of diffuse type HCC four showed extrahepatic supplying arteries,and in nine cases of nodular type HCC only one had extra-hepatic supplying arteries. The HCC could get their extrahepatic blood supply via eight pathways. A total of 44 extrahepatic supplying arteries were detected,and 19 anomalously originated hepatic arteries were found. Conclusion The extrahepatic supplying arteries in hepatocellular carcinoma are common findings and their supplying pattern are extremely varied,which may be associated with the type and location of the tumors. Three-dimensional reconstruction technique with the help of triple-phase enhanced CT scanning on a 64-slice spiral CT scanner can provide excellent images as vivid and ideal as angiography can afford. Therefore,the times of angiography examination,the use of contrast media as well as the dose of radiation to both the patients and the physicians can be reduced as far as possible. The detailed information about extrahepatic blood supply is very useful for improving the therapeutic result of HCC.
7.Effect of low dose radiation on apoptosis of transplantation tumor cells of human glioma(U251)-bearing nude mice
Hongyu JIANG ; Jun FU ; Jinghan YANG ; Zhenhua LIN ; Guanju WANG
Journal of Jilin University(Medicine Edition) 2006;0(05):-
0.05). While in D_2 and D_1+D_2 groups, the AI (0.54?0.05,0.64?0.04,0.63?0.04,0.65?0.11, 0.67?0.07) were increased, and the latter was more obviously. There were significant differences compared with sham-irradiated group(P
8.Advances in biomarkers of ARDS
Xuan FU ; Jinle LIN ; Wenwu ZHANG ; Lijun WANG
Chinese Critical Care Medicine 2017;29(7):656-661
Acute respiratory distress syndrome (ARDS) is a common diseases in critical ill patients, which is an acute-onset hypoxic condition with radiographic bilateral lung infiltration. And it can be divided into two phases in pathophysiology: an acute exudative phase combining diffuse alveolar damage and lung edema followed by a later fibro proliferative phase. The early prediction and risk assessment of patients with ARDS is still very poor in the clinical. In recent years, researchers gradually focus their research on exploration of biomarkers of ARDS. The article mainly aims to sum up the development of biomarkers exploration.
9.Application and research progress of starch in polymer materials
Zhifen WANG ; Lin FANG ; Kexi ZHANG ; Xin FU
Chinese Journal of Tissue Engineering Research 2008;12(19):3789-3792
Starch a natural polymer that is characterized by cheap, regenerative, and good biodegradation is generally mixed with low density polyethylene, high density polyethylene, polypropylene, and polystryrene to prepare degradable materials. In order to relieve "white pollution" due to undegradability of plastic materials, starch is mixed with polyvinyl alcohol, polylactic acid, poly-hydroxybutyric acid, polycaprolactone, chitosan, derivatives, and other degradable polymers to prepare fully degradable biomaterials. With gradual exhaustion of petroleum and progressive depravation of environmental quality, starch that is regarded as a reinforcing agent is widely used in rubber industry. Starch is characterized by hydrophilicity, difficulty in processing, and poor compatibility to plastic materials, rubber, and other polymers, so starch is firstly modified and then mixed with polymers to make starch. This study was designed to summarize the application of starch in plastic materials, rubber, and other polymer blends and to investigate the latest research progresses of starch in polymer materials.
10.The clinical application of CT-guide percutaneous biopsy in the pulmonary nodules
Jinsong LIN ; Fu RONG ; Liuer ZUO ; Hao WANG
Chinese Journal of Primary Medicine and Pharmacy 2008;15(2):283-284
Objective To explore the diagnosis value of CT-guide percutaneous biopsy in the pulmonary nodules.Methods A total of 101 cases of the pulmonary nodules with unknown causes who underwent Germany-made auto-spring-gun spiral CT-guide percutaneous pulmonary biopsy were studied.Results The accuracy of centesis was 100%.97 cases were succeeded in getting diagnosis,the diagnosis rate was 96.0%.Among them,there were 61 cases of lung cancer,4 cases of malignant pleural mesothelioma,10 cases of metastatic carcinoma,16 cases of tuberculosis,6 cases of inflammatory pseudotumor.Pneumothorax occurred in 8 cases,hemoptysis occurred in 3 cases.The rate of complication was 10.9%.Conclusion CT-guide percutaneous biopsy to the pulmonary nodules is a safe and effective diagnostic means,which has a high diagnosis raze with few complication.