OBJECTIVE:To study the effect of Herba Siegesbeckiae capsule on cerebral blood flow (CBF), cerebral vessel resistance (CVR), blood pressure (BP), electrocardiogram (ECG) and heart rate (HR)in anesthetized dogs. METHODS: The external carotid arteries on one side and the vertebral arteries of dogs were ligated, then the CBF of carotid arteries was measured by electromagnetic flowmeter, and the BP, EGG and HR were measured by polygraph. RESULTS: Herba Siegesbeckiae capusle could significantly increase CBF and decrease CVR; however, it has no effect on BP, ECG and HR. CONCLUSION: Herba Siegesbeckiae capsule can improve cerebral blood circulation through increasing CBF and decreasing CVR.

OBJECTIVE: To compare the protective effects of two fasudil hydroehloride injections (trade name: Yililu vs. Chuanwei) on experimental cerebral ischemia of rats. METHODS: A total of 60 SD rats were randomly divided into sham opertion group, model group, Yililu group, Chuanwei high dose group, and Chuanwei low dose group. Cerebral ischemia model was made in each group for the observation of the effects of fasudil hydroehloride injections on the neuralogical function, cerebral infarction size and the pathomorphology of brain tissues. RESULTS: As compared with model group, two kinds of the fasudil hydroehloride injections at the same dose identically decreased the score of neurological function as well as the cerebral infarction size, and lessened the degree of the pathomorphological change of brain tissues (P0.05). CONCLUSION: The two kinds of fasudil hydroehloride injections showed an equivalent protective effect on the damage of experimental cerebral ischemia.

AIM: To explore the curative effect of different ways of silicone tube catheter for the treatment of children`s lacrimal canaliculi rupture.METHODS: A retrospective analysis from January 2014 to December 2015 were taken.According to admission time sequence,42 children with lacrimal canaliculi rupture was divided into two groups.One group was treated with single silicone tube insertion,the other was treated with annular silicone tuber insertion.The treatment results were comparatively analyzed.RESULTS: There were 4 eyes in single silicone tube group occurred fall off in 2wk to 1mo after operations because of improper nursing and the second operations were taken.There was no eye with this in annular silicone tuber groups,the difference between the two groups was significant(P<0.05).In single silicone tube group,16 eyes were cured,1 eye improved,3 eyes unchanged which were the 3 eyes with fall off.Those 3 eyes were 1 patient bitten by dog,2 bombed;the effective rate was 85%.In annular silicone tuber insertion,20 eyes were cured,2 eyes improved and the effective rate was 100%,the difference between the two groups was significant (P<0.05).CONCLUSION: Children`s lacrimal canaliculi rupture should be timely given surgical treatment,reasonable surgical treatment can achieve good operation effect.Annular silicone tube has good stability,fewer complications than single silicone tube,and clinical treatment effect is good.

Objective To investigate the expression of miR-200b in lung cancer and its relationship with clinicopathological features of lung cancer.Methods The specimens of lung tumor tissue and adjacent normal lung tissue of 36 cases of lung cancer who received surgical treatment in our department were collected,and then quantitative real time PCR (qRT-PCR) was applied to determine the expression of miR-200b in lung cancer tissue and adjacent normal lung tissue.Results The expression of miR-200b in lung cancer was significantly lower than adjacent normal lung tissue (P =0.000),and in small cell lung cancer was also significantly lower than adenocarcinoma and squamous cell carcinoma (0.13 ± 0.09 vs.0.64 ± 0.33,0.75 ± 0.30) (P =0.005 and P =0.001).The expression of miR-200b in patients with positive lymph nodes,advanced stage of lung cancer and in smokers were significantly lower than those with negative lymph nodes,early stage of lung cancer and in non-smokers,respectively (0.52 ± 0.29 vs.0.87 ± 0.35,0.46 ±0.25 vs.0.90 ±0.32,0.52 ±0.27 vs.0.90 ±0.39) (P =0.004,P =0.000 and P =0.015).Conclusions Low expression of miR-200b may participate in the occurrence and progression of lung cancer,especially in small cell lung cancer,and correlates with the metastasis of lung cancer.The down-regulated expression of miR-200b may be induced by smoking.Thus,miR-200b perhaps is a new target for the treatment of lung cancer.

Biopsy ; Carcinoma, Hepatocellular ; diagnosis ; Diagnostic Errors ; Fatal Outcome ; Humans ; Liver ; diagnostic imaging ; pathology ; Liver Neoplasms ; diagnosis ; Male ; Middle Aged ; Splenectomy ; Splenic Diseases ; diagnosis ; surgery ; Tomography, X-Ray Computed

OBJECTIVE To understand the nurses′ awareness of specimen collection and explore the impact of acquisition-related factors and provide the basis for standardized training.METHODS A questionnaire was designed for specimen collection survey about microorganisms in level-3 hospital.RESULTS 90.38 percent of nurses consulted the laboratory,80.77 percent communicated with other nurses to solve the problom about microbiology specimen collection and 94.2% thought it necessary about continuing education.The ward nurses′ knowledge about microbiology specimen collection was better than these from surgical department.CONCLUSIONS It is urgent that stundard training of specimen collection should be implement in medintely due to lacking the awareness.

Objective To explore the effect of dressing techniques under Orem self-care theory on the ability of daily living of stroke patients with hemiplegia. Methods About 96 stroke patients with hemiplegia were randomly divided into an experimental group and a control group, 48 cases in each group. The patients in the experimental group received training on dressing techniques under Orem self-care theory, while those in the control group received routine training on dressing techniques.The daily life ability of both groups was comfared. Result After one month, the Barthel scores in the experimental group were higher than those of the control group (P<0.05). Conclusion Dressing techniques under Orem self-care theory can improve the ability of daily living of stroke patients with hemiplegia.

Objective To find out factors influencing voluntary blood donation activities and establish the most appropriate method for recruiting blood donors. Methods Questionnaire investigation of donors and data analysis by SPSS+ software. Results In Chengdu city, 2385 residents' knowledge on nonrenumerated blood donation was as follows: among the 2385 residents, the percentage of people who knew the government policies of blood donation was high (87.5%), but the percentage having common knowledge of blood donation was only 29.4%, of risk behavior was 32.5%. Among the 1349 participants who had donated blood, the percentages having common knowledge of blood donation and risk behavior were 33.4% and 38.1% respectively, compared to the 1036 participants who never donated (24.2% and 25.1%, respectively)(P

Breast cancer is one of the most common malignant tumours in women. It threatens the health and life of women. The imaging technology of breast electrical impedance scanning based on the dielectric properties of breast tissues develops a new aspect of early detection and auxiliary diagnosis of the breast cancer. The dielectric properties of human breast tissues reflect the pathological and physiological state of breast tissues and the measurement of these properties serves as the basis for electrical impedance scanning(EIS) technology. In this paper, the measurements and results of dielectric properties of human breast tissues are discussed, and the problems of measurement and the application perspective of the EIS are also explored.

Varicella zoster virus (VZV) is a widespread human herpesvirus which causes chickenpox (varicella). VZV infection can produce a broad spectrum of neurologic disorders including multiple cranial nerve palsies. Among the cranial nerves, trigeminal and facial nerves are the most commonly involved. However, multiple lower cranial nerve palsies caused by VZV infection is very rare. It is a diagnostic dilemma for VZV infection if there are no skin or mucosa lesions, which are characteristic signs of VZV infection. We report the case of a 54-year-old man with sudden right hearing loss, sore throat, odynophagia, hoarseness, dysphagia and vertigo. Pure tone audiometry revealed right sensorineural hearing loss and laryngoscopy proved that there were paralyses of the right upper pharyngeal constrictor muscle and vocal cord. These findings were consistent with acute unilateral vestibulocochlear, glossopharyngeal and vagus nerve palsies. There were no skin or mucosa lesions noted in our patient. The diagnosis was assisted by the existence of anti-VZV serum IgM even if the polymerase chain reaction result was negative. The symptoms of the patient improved after receiving anti-viral therapy. We emphasize the role of VZV infection in multiple cranial nerve palsies and the importance of serologic test.
Herpesvirus 3, Human ; Cranial Nerve Diseases