No abstract available.
Fentanyl ; Syringes

Effect of marcaine plus fentanyl combination for lumbar epidural anesthesia was investigated in random series of 33 patients who were undergoing lumbar discectomy. Patients received 1mg/kg marcaine with 1mcg/kg fentanyl. The volume of local anesthetic solution was calculated basing on the number of segments that needed to block: 1.5 - 1.6ml per segment. It was found that the marcaine plus fentanyl combination provided high effect (100%) on epidural anesthesia, rapid onset (7.51.8 min), long working duration (33070 min), caused milder hemodynamic changes, decreased the incidence of adverse events and produced satisfactory operating condition.
Bupivacaine ; Fentanyl ; Anesthesia, Epidural

A prospective study involved 64 patients (43 men, 21 women) aged from 20 to 62 years with lumbar disc herniation who had operated at Military Hospital 103. These patients were divided into 2 groups. Group 1 received marcaine (0.25%-0.375%) plus fentanyl, group 2 received marcaine (0.35% - 0.5%) alone for lumbar epidural anesthesia. The volume of local anesthetic solutions injected epidurally was calculated based on number of segments that had to block, with dose of 1.5 - 1.6 ml per segment. The results showed that compare with marcaine alone, the combination of marcaine and fentanyl provided better analgesic effect, faster onset and longer duration of action, caused milder hemodynamic changes, decreased the incidence of adverse effects and produced satisfactory post-operative condition
Bupivacaine ; Fentanyl ; Analgesia, Epidural

No abstract available.
Amides ; Arthroplasty ; Fentanyl ; Knee

Diprivan is intravenous anesthetic agent with many advantages. 20 patients received the diprivan for abdominal fatty removal. The results have shown that the homodynamic during operation was stable. The hypotension occurred only during preanasthesics. The heart beat was also reduced due to the change of sensitivity of sensory focus and pressure reflex, this reduction was corresponded with hypotension but within allowed range. These easily controlled and were stable throughout an operation
Propofol ; Fentanyl ; surgery

No abstract available.
Fentanyl ; Intensive Care Units ; Miliaria*

BACKGROUND: We designed this study to find the appropriate dose of fentanyl for the prevention of emergence agitation in pediatric tonsillectomy patients under sevoflurane anesthesia. METHODS: Sixty pediatric patients receiving sevoflurane anesthesia for tonsillectomy was assigned to 3 groups. Fentanyl 0.5microgram/kg (group 1), 1.0microgram /kg (group 2), or 1.5microgram/kg (group 3) was administered intravenously 10 min before the end of surgery. Agitation score was checked at the postanesthesia care unit. RESULTS: The results showed a lower incidence of severe agitation in groups 2 and 3 than in group 1. There was no difference between groups 2 and 3. CONCLUSIONS: For preventing emergence agitation after sevoflurane anesthesia, we recommend using fentanyl in a dose of more than 1.0micrgram/kg.
Anesthesia* ; Dihydroergotamine* ; Fentanyl* ; Humans ; Incidence ; Tonsillectomy*

BACKGROUND: This study compared the efficacy of intravenous fentanyl with lidocaine as a pretreatment for the prevention of a withdrawal response after a rocuronium injection. METHODS: Eighty patients were divided into four groups according to the drugs used for pretreatment as follows: group I: normal saline, group II: lidocaine 0.5 mg/kg, group III: lidocaine 1.0 mg/kg, group IV: fentanyl 1microgram/kg. Twenty seconds after inducing anesthesia, each pretreatment drug was injected. After twenty seconds, rocuronium was injected. The incidence and severity of the withdrawal responses was assessed. The BIS value and heart rate was recorded at each point (T0: baseline, T1: pretreatment drug injection, T2: 10 seconds after pretreatment drug injection, T3: rocuronium injection, T4: 10 seconds after rocuronium injection, T5: 20 seconds after rocuronium injection). RESULTS: The incidence of withdrawal movement was significantly lower in groups II and III than in groups I and IV (P = 0.002). The BIS was significantly lower in group IV than in groups I, II and III at T2 and group I at T3 (P < 0.05). The heart rate at T4 was significantly lower in group IV than in group II (P < 0.05). An assessment of BIS at the withdrawal movements showed a significantly higher value in the severe group than in the none and mild groups at T5 (P < 0.05). CONCLUSIONS: A pretreatment with 0.5 mg/kg or 1.0 mg/kg of lidocaine effectively reduced the incidence of a withdrawal response by the rocuronium injection. However, 1.0 mg/kg of lidocaine most effectively prevented the withdrawal response without causing any significant changes in heart rate.
Anesthesia ; Fentanyl* ; Heart Rate ; Humans ; Incidence ; Lidocaine*

The influence of clonidine on the analgesic effect of epidural fentanyl was investigated in 45 patients who underwent total abdominsl hysterectomy by epidural admistration of fentanyl 100 g alone, clonidine 150ug alone, or in combination of the two drugs. Changes in the mean arteral pressure and pulse rate were observed after drug administration, and the analgesic effects was assessed by measuring analgesic duration, pain score, sedation score, and side effects. Analgesic duration was prolonged with improved quality by adding 150 ug of clonidine to 100 ug of epidural fentanyl. Mean arteral pressure and pulse rate were decreased more in fentanyl plus clonidine group than each drug alone group. But these changes were restored rapidly by injection of small dose of vasopressor. The clonidine alone group showed the least analgesic effect among three groups indicatings that clonidine would not be a sole analgesic agent and would be used as an adjunct to other opiate such as fentanyl.
Clonidine* ; Fentanyl* ; Heart Rate ; Humans ; Hysterectomy

BACKGROUND: Intrathecal opioid, a useful adjunct to prolong analgesic effects, potentiates spinal anesthesia. The present study was designed to evaluate the effect of intrathecal fentanyl on the hypnotic requirements of propofol during spinal anesthesia. METHODS: Sixty patients scheduled for elective urologic surgery under spinal anesthesia were randomly assigned to one of four groups. In Group 1 (n =15), spinal anesthesia was performed with hyperbaric bupivacaine 10 mg, in Group 2 (n = 15) with hyperbaric bupivacaine 10 mg plus fentanyl 10microgram, in Group 3 (n = 15) with hyperbaric bupivacaine 10 mg plus fentanyl 20microgram, and in Group 4 (n = 15) with hyperbaric bupivacaine 10 mg plus fentanyl 30microgram. After performing spinal anesthesia, the target plasma concentration of propofol was set at 2.0microgram/ml. Effect site concentration (Ce) was measured when the BIS's reached 80 or 70. Ce was titrated to maintain a BIS of 70-80. Observer's sedation scoring (OAA/S), systolic and diastolic pressures, SpO2 and total infusion dose were measured every 10 minutes for 1 hour. RESULTS: Ce's at a BIS of 80 were 1.2+/-0.3microgram/ml (Group 1), 1.0+/-0.3microgram/ml (Group 2), 0.9+/-0.2microgram/ml (Group 3), and 0.8+/-0.2microgram/ml (Group 4), respectively. Ce's at a BIS of 70 were 1.6+/-0.2microgram/ml (Group 1), 1.5+/-0.4microgram/ml (Group 2), 1.2+/-0.3microgram/ml (Group 3), and 1.2+/-0.3microgram/ml (Group 4), respectively. Ce's of Group 3 and Group 4 at BISs of 70 and 80 were significantly lower than those of Group 1 (P<0.05), and the propofol requirements of Groups 3 and 4 to maintain a BIS of 70-80 were significantly less than those of Group 1 (P<0.05). CONCLUSIONS: These results indicate that adding more than 20microgram of fentanyl to hyperbaric bupivacaine for spinal anesthesia reduces the hypnotic requirement of propofol.
Anesthesia, Spinal* ; Bupivacaine ; Fentanyl* ; Humans ; Plasma ; Propofol*