No abstract available.
Fentanyl ; Syringes

Effect of marcaine plus fentanyl combination for lumbar epidural anesthesia was investigated in random series of 33 patients who were undergoing lumbar discectomy. Patients received 1mg/kg marcaine with 1mcg/kg fentanyl. The volume of local anesthetic solution was calculated basing on the number of segments that needed to block: 1.5 - 1.6ml per segment. It was found that the marcaine plus fentanyl combination provided high effect (100%) on epidural anesthesia, rapid onset (7.51.8 min), long working duration (33070 min), caused milder hemodynamic changes, decreased the incidence of adverse events and produced satisfactory operating condition.
Bupivacaine ; Fentanyl ; Anesthesia, Epidural

A prospective study involved 64 patients (43 men, 21 women) aged from 20 to 62 years with lumbar disc herniation who had operated at Military Hospital 103. These patients were divided into 2 groups. Group 1 received marcaine (0.25%-0.375%) plus fentanyl, group 2 received marcaine (0.35% - 0.5%) alone for lumbar epidural anesthesia. The volume of local anesthetic solutions injected epidurally was calculated based on number of segments that had to block, with dose of 1.5 - 1.6 ml per segment. The results showed that compare with marcaine alone, the combination of marcaine and fentanyl provided better analgesic effect, faster onset and longer duration of action, caused milder hemodynamic changes, decreased the incidence of adverse effects and produced satisfactory post-operative condition
Bupivacaine ; Fentanyl ; Analgesia, Epidural

Diprivan is intravenous anesthetic agent with many advantages. 20 patients received the diprivan for abdominal fatty removal. The results have shown that the homodynamic during operation was stable. The hypotension occurred only during preanasthesics. The heart beat was also reduced due to the change of sensitivity of sensory focus and pressure reflex, this reduction was corresponded with hypotension but within allowed range. These easily controlled and were stable throughout an operation
Propofol ; Fentanyl ; surgery

No abstract available.
Amides ; Arthroplasty ; Fentanyl ; Knee

No abstract available.
Fentanyl ; Intensive Care Units ; Miliaria*

Stress cardiomyopathy is characterized by transient systolic dysfunction of the apical and/or mid segment of the left ventricle. The main pathophysiology of stress cardiomyopathy is the excessive release of catecholamine. Opioid withdrawal can initiate a surge of catecholamine and an attack of stress cardiomyopathy. In this case, we report a case of stress cardiomyopathy due to iatrogenic withdrawal from transdermal fentanyl.
Aged* ; Fentanyl* ; Heart Ventricles ; Humans ; Takotsubo Cardiomyopathy*

At the National Institute of Burn, from January 2001 to April 2003, 45 subjects (21 males, 24 females, aged 16-67 years old) were operated for burn and underwent a plastic surgery for burn on the areas of chest, abdomen, sex organs and inferior limbs. Epidural anaesthesia was performed with bupivacain 0.5% x 1.25mg/kg, fentanyl 0.01 x 1 microgram/kg, adrenaline 1% x 3 drops. Good result was reached according to Bromage clanification score. There was no case needing other method of anesthsia. Common post-operative side effects were mild headache and urine retention. This anaesthesia was a good method, simple and safer for burn surgeries.
Anesthesia ; Bupivacaine ; Fentanyl ; Therapeutics ; Surgery ; Burn

BACKGROUND: Intrathecal opioid, a useful adjunct to prolong analgesic effects, potentiates spinal anesthesia. The present study was designed to evaluate the effect of intrathecal fentanyl on the hypnotic requirements of propofol during spinal anesthesia. METHODS: Sixty patients scheduled for elective urologic surgery under spinal anesthesia were randomly assigned to one of four groups. In Group 1 (n =15), spinal anesthesia was performed with hyperbaric bupivacaine 10 mg, in Group 2 (n = 15) with hyperbaric bupivacaine 10 mg plus fentanyl 10microgram, in Group 3 (n = 15) with hyperbaric bupivacaine 10 mg plus fentanyl 20microgram, and in Group 4 (n = 15) with hyperbaric bupivacaine 10 mg plus fentanyl 30microgram. After performing spinal anesthesia, the target plasma concentration of propofol was set at 2.0microgram/ml. Effect site concentration (Ce) was measured when the BIS's reached 80 or 70. Ce was titrated to maintain a BIS of 70-80. Observer's sedation scoring (OAA/S), systolic and diastolic pressures, SpO2 and total infusion dose were measured every 10 minutes for 1 hour. RESULTS: Ce's at a BIS of 80 were 1.2+/-0.3microgram/ml (Group 1), 1.0+/-0.3microgram/ml (Group 2), 0.9+/-0.2microgram/ml (Group 3), and 0.8+/-0.2microgram/ml (Group 4), respectively. Ce's at a BIS of 70 were 1.6+/-0.2microgram/ml (Group 1), 1.5+/-0.4microgram/ml (Group 2), 1.2+/-0.3microgram/ml (Group 3), and 1.2+/-0.3microgram/ml (Group 4), respectively. Ce's of Group 3 and Group 4 at BISs of 70 and 80 were significantly lower than those of Group 1 (P<0.05), and the propofol requirements of Groups 3 and 4 to maintain a BIS of 70-80 were significantly less than those of Group 1 (P<0.05). CONCLUSIONS: These results indicate that adding more than 20microgram of fentanyl to hyperbaric bupivacaine for spinal anesthesia reduces the hypnotic requirement of propofol.
Anesthesia, Spinal* ; Bupivacaine ; Fentanyl* ; Humans ; Plasma ; Propofol*

BACKGROUND: Rocuronium bromide is a monoquaternary amino steroidal muscle relaxant. Rocuronium is structurally stable and no metabolites of rocuronium have not been observed in humans. The manufacturer recommends that rocuronium can be stored in room temperature for 12 weeks. The aim of this study was to determine if the storage temperature of rocuronium could influence the pharmacodynamics of rocuronium. METHODS: One hundred of patients with a class I or II ASA physical status were enrolled in this study. It was divided to two groups. One (Group '0', n = 50) consists of those who had intravenously administered the rocuronium which had been stored in refrigerator and the other (Group '14', n = 50) consists of those who had intravenously administered the rocuronium which had been stored in room temperature (20-29degrees C, median 25.1degrees C) for 14 days. Before an anesthesia was induced, TOF-Watch(R) was attached and calibrated. The anesthesia was induced with 1microgram/kg of fentanyl and 1.5 mg/kg of propofol intravenously. While the 0.1 Hz of single twitch was applied, 0.45 mg/kg of rocuronium, which is appointed to each group, was injected. Intubation is performed 90 seconds after injection of rocuronium and evaluated the intubating condition as excellent, good, poor, and impossible. RESULTS: There was a statistically significant difference in intubating condition at 90 seconds between two groups. The onset time to twitch depression of 0% in group '14' was prolonged compared to group '0' (P < 0.05). Clinical duration was also shortened in group '14' (P < 0.05). CONCLUSIONS: Compared with the use of rocuronium stored in refrigerator, that stored at room temperature can be expected to have unfavorable intubating condition at 90 seconds after rocuronium injection. Therefore, the storage temperature has some influences on the efficacy of rocuronium.
Anesthesia ; Depression ; Fentanyl ; Humans ; Intubation ; Propofol