Objective To study the effect of motivational interview on health education to patients with diabetes.Methods Fifty patients with diabetes were randomly divided into the control group and the intervention group by using random digit table.The control group was given routine health education and the latter motivational interview.The two groups were compared in terms of self-efficacy and fasting blood sugar and glycated hemoglobin indexes.Result The self-efficacy,fasting blood sugar and glycated hemoglobin indexes in the intervention group were all better than those of the control group(P<0.01).Conclusion Motivational interview can effectively improve the patients’self-efficacy,do good for controling blood sugar level and meanwhile improve the quality of health education.

BACKGROUNDTo evaluate the diagnostic values of multiple tumor marker protein biochip detective system for lung cancer.

METHODSThe serum levels of 12 tumor markers, including CA199, NSE, CEA, CA242, CA125, CA153, AFP, ferritin, free-PSA, PSA, β-HCG and HGH, were measured in 108 lung cancer patients, 48 patients with benign pulmonary lesion and 145 healthy by the detective system.

RESULTSThe positive rates were 83.33% (90/108), 52.08% (25/48) and 28.97% (42/145) in lung cancer, benign pulmonary lesion and healthy groups, respectively. The lung cancer group had significantly higher positive rate than that of the controls (Chi-Square=16.75 and 73.32, both P < 0.001); There was significant difference of positive rate in various clinical stages of lung cancer (Chi-Square=7.89, P=0.048), but not in different pathologic classification. Serum CA199, CEA and CA242 levels were closely correlated with clinical staging (F=2.84, P=0.041; F= 3.49, P=0.018; F =5.22, P=0.002). The positive rate of CEA in adenocarcinoma was higher, but no significant difference was observed (Chi-Square=0.71, P=0.07). NSE in small cell lung cancer had the highest positive rate (Chi-Square=19.03, P < 0.001). Combined measurement of the twelve markers had higher sensitivity (Chi-Square= 368.58, P < 0.001), but less specificity (Chi-Square= 369.87, P < 0.001).

CONCLUSIONSCombined measurement of various serum tumor markers using protein biochip can significantly increase the diagnostic sensitivity for lung cancer. Meanwhile, it is also significant for defining clinical stage, identificating pathologic classification, as well as monitoring therapeutic efficacy. As its specificity and positive predictive value are lower, it is more suitable to be used as a surveying tool for symptomless people, especially for high risk people for lung cancer.