Objective To discuss the skills, safety and feasibility of the long stent implants in the middle cerebral artery in brain. Methods One 58-year-old female patient suffered from recurrent right limb dysfunction was chosen as the subjective. The cerebral angiography showed long stenosis lesions (90%-95% )in left middle cerebral artery from M1 to M2, with the length of 13 - 14 mm and the vascular diameter of 2. 5mm. Under local anesthesia a 2. 5 mm × 15.0 mm rapamycin-eluting stent was implanted into left middle cerebral artery. Results The stent was successfully implanted with no residual stenosis, and with TIMI 3 level blood flow. The patient had no adverse events during 14-month follow up. Conclusion With good implanting skills,long stent implantation in middle cerebral artery is safe and feasible.