Objective To study the relationship between expression of p75 gene and apoptosis of cerebrum cells in type 2 diabetic rats.Methods Ten type 2 diabetic rats and ten natural rats were used to test the expression of brain p75 mRNA by RT-PCR technique, and the apoptosis of cerebrum cells was measured by agarose gel electrophoresis (AGA).Results The expression of brain p75 mRNA and apoptosis of cerebrum cells in type 2 diabetic rats were higher than that of the natural group.Conclusion The apoptosis of cerebrum cells in type 2 diabetic rats increases, and it is positively correlated with the expression of brain p75 gene mRNA.

Formative evaluation is a medical education evaluation form used to correct its own track in the course of activities so as to get better effect. In the medical education, it can significantly improve the medical students' ability such as active learning ability, relearning ability, ability to master and apply know l edge, ability of scientific thinking and debating, ability of innovation and analysis, ability of association and communication, and so on.

Objective To investigate the current learning status of medical students and related influencing factors, and to improve the quality of medical education. Methods The method of formative assessment and summative assessment was used. Questionnaire survey and data collection were performed among 11760 students from 11 medical colleges and universities in China to analyze their learning motivations, learning attitudes, academic record, and expectations. An analysis of variance and the t-test were used for comparison of general demographic factors. Results The overall score of learning motivations was (1.95±0.57) points (with a full score of 3 points), while there were significant differences between the colleges and universities in different regions , the colleges/universities at different levels , and different specialties (F=49.694, 12.354, and 8.094, P<0.01). The overall score of self-appraised learning attitudes was (2.68±0.78) points (with a full score of 4 points), and there were significant differences between the medical students from different regions, different types of colleges/universities, and colleges at different levels, between the medical students with different sexes, specialties, and grades, and between the military and non-military medical students (F/t=49.476, 19.241, 57.275, 11.513, 4.660, 30.177, and 42.788, P<0.01). The score of expectations for academic record was (2.14±0.95) points (with a full score of 4 points), and there were significant differences between different groups of medical students (F/t=458.503, 149.679, 553.090, 409.184, 29.584, 199.268, and 821.113, P<0.01). The score of overall academic record was (2.43±0.79) points (with a full score of 4 points), and there were significant differences between different groups of medical students (F/t=44.938, 20.305, 47.850, 45.174, 3.769, 20.819, and 81.909, P<0.01). There were significant differences in academic record between the medical students with different learning motivations , expectations , and self-appraised learning attitudes ( F/t=78 . 845 , 1146.000, and 715.012, P<0.01). Conclusion Medical students in China generally have good learning status, which is greatly influenced by general demographic factors. The academic score of medical students in China is positively correlated with learning expectations and attitudes , and learning motivations have a special effect on academic record.

Objective To investigate the diagnostic value of Enzymes linked immunosorbent assay(ELISA)detection of anti phospholipase A2 receptor antibody(anti-PLA2R)in idiopathic membranous nephropathy patients.Methods All articles published from January 2012 to April 2017 about ELISA test on anti phospholipase A2 recepeor antibody as a maker for IMN were collected, and the quality of the studies was evaluated by using the guidelines of the updated Quality Assessment of Diagnostic Accuracy Stud-ies(QUADAS-2)tool.According to the inclusion criteria and exclusion criteria,the research objects were selected and the data were extracted,and the analysis was carried out by Meta-Disc1.4 software.The results are summarized on the basis of sensitivity,speci-ficity,and summary receiver operating characteristic curve(ROC curve).Results Ten articles were selected according to inclusion criteria and 1517 cases were included in the study.The combined sensitivity was 0.68[95% CI(0.64,0.70)];the merge specificity was 0.92[95% CI(0.90,0.95)],and the subjects'working curve showed AUC 0.807 4.Conclusion The detection of anti-PLA2R by ELISA is effective in the diagnosis of idiopathic membranous nephropathy,which can be used as an effective supplement for the diagnosis of idiopathic membranous nephropathy.

Objective:Taking naval officers and soldiers who participate in military continuing education as an example, to compare the distribution of sensory learning style of learners with different personality in order to provide suggestions and references for online course teaching.Methods:By using convenient sampling method, MBTI (Myers-Briggs Type Indicator) and VARK (Visual, Aural, Read/Write, Kinesthetic questionnaire) were measured in the Navy. A total of 10 000 questionnaires were distributed and 8 124 valid ones were collected. Through analysis of SPSS 25.0 software, the personality dimensions and personality types were analyzed for personality analysis, and the main indicators of sensory learning style analysis were tendency multiplicity, the intensity and distribution of single sensory learning style, and specific sensory learning styles. The Chi-square test was adopted, with test level of α=0.05. Results:It showed statistical differences in the tendency multiplicity and intensity of single style among officers and soldiers in the three dimensions of extroversion-introversion, sensing-intuition and judging-perception ( χ 2=12.37, 18.02, 22.97, 12.57, 12.73, 24.45, P=0.005, <0.001, <0.001, =0.006, =0.005, <0.001). It showed statistical differences in the distribution of single style and the specific sensory learning styles among officers and soldiers in all the four dimensions of extroversion-introversion, sensing-intuition, thinking-feeling, and judging-perception ( χ 2=28.30, 36.96, 11.40, 41.95, 53.76, 75.48, 43.11, 77.29, P <0.001, <0.001, =0.022, <0.001, <0.001, <0.001, <0.001, <0.001). It showed statistical differences in the tendency multiplicity, the intensity and distribution of single style, and the specific sensory learning styles among naval officers and soldiers with different personality types ( χ 2=86.63, 96.22, 147.41, 363.76, all P<0.001). Conclusions:Personality dimension has influence on sensory learning style, especially for extroversion-introversion, sensing-intuition, and judging-perception dimensions. Personality type has an important influence on the tendency multiplicity, distribution type and performance intensity of sensory learning style. It is integral part of online course teaching to meet the diversified and personalized learning needs of officers and soldiers.