Objective To analyze the epidemiology of patients with diseases to be treated by internal medicine physicians present in the emergency department.Methods A retrospective analysis of the data of patients under observation in the emergency department of the affiliated hospital of Inner Mongolia Medical University admitted from Jan.1 2014 through Jan.1 2015 was carried out.The records including patients' name,age,gender,type of diseases,time required for complete resolution of the disease and outcome of patients were kept.The data were analyzed with SPSS 17.0 version software,and x2 test was used to compare the difference in incidence.Results There were a total of 13842 patients with 53％ male and (58.21 ± 17.43) years of average age.The highest proportion of patients kept in emergency room for observation was in 60-74 years old group.The number of patients paying a visit to the doctor peaked during 12-24 o'clock and there were two max-peaks at 18,and 22 o'clock.There was a significant increase in number of patients in March,April and Dec.with the highest number in March and the lowest number in July.Respiratory diseases,cardiovascular disease and neurological diseases were the major prevalence diseases in the seasonal spectrum accounting for 64.56％ of the total number.Between July and August,a large number of patients suffering from outbreak of allergic asthma were flocking to hospital after a shower of heavy rain.Conclusion A more attention should be paid to the middle-aged people of this kind.According to the prevalence features of the diseases,the appropriate and reasonable arrangements of medical workers & medical resources should be planned out so as to increase the survival rate of emergency patients.

The construction of campus culture is all-around systemic project with quite abundant content.However,medical morality is indispensable in the construction of campus culture.This article concretely analyzes status of medical morality,expatiates on effect of medical morality in the construction of campus culture.Further,a discussion on the approach of medical morality which combines medical morality and the construction of campus culture is given.

Objective The metabolomics methods were applied to discover the serum differences metabolites in patients with lupus nephritis (LN),and to establish the diagnostic model and study the metabolic pathways change due to the interference of LN and explore the pathogenesis of LN.Methods Positive and negative ions mode of ultra high performance liquid chromatography-high resolution mass spectrometry (HPLS-HRMS) were used to analyze the serum samples of 38 LN patients and 35 healthy controls,respectively.Both univariate and multivariate data analysis were performed with SPSS software (V17.0,Chicago,USA) and SIMCA-P+ package (V12.0,Umetrics,Sweden),respectively.A supervised pattern recognition method,orthogonal partial least squares-discriminant analysis (OPLS-DA),was employed to study the metabolomics differences between control group and LN patients group.The metabolic pathways were analyzed by Metabo Analyst 3.0.Results LN patients and healthy controls could be well separated by OPLS-DA model Q2 of 0.583.Eighteen compounds (theophylline,oxidized glutathione,capric acid,norvaline,hippuric acid,sphingosine,sorbitol,cortisol,pyrrole-2-carboxylic acid,deoxycholic acid,tryptamine,5-aminolevulinic acid,glucose 6-phosphate,riboflavin,cortisone,taurine,creatinine,glycerophosphocholine) were initially identified as potential serum metabolic markers to distinguish LN patients from healthy people.Alternated metabolism pathways included citrate metabolism,pyrimidine metabolism and amino acid metabolism.Conclusion Through analysis of the metabolic pathways of different metabolites,the significant impact of LN on citrate metabolism,pyrimidine metabolism and amino acid metabolism pathways are identified.Some of the different metabolites are involved in the process of immunization.These results will benefit the early intervention and treatment of LN and the research of the mechanism of pathogenesis.

This paper summarize the perioperative nursing of 12 newborns with thyroglossal cyst. The preoperative nursing measures focused on prone position,gastric tube feeding,close monitoring of vital signs and tracheal intubation as needed. If the TeSO2 was normal,oxygen therapy was not recommended. After the operation,continuously monitoring vital signs,respiratory care and use of sedatives as needed were carried out. As a result,all of the 12 infants recovered and discharged.

Objectives:The purpose of this study is to explore the teaching effect in flipped classroom stragety of nursing ethics curriculum based on learning ability,so as to provide reference for cultivating ethical thinking of nursing students and promoting their learning ability.Methodts:This study used flipped classroom stragety based learning ability in nursing research ethics section of nursing ethics curriculum,nursing students had a quiz last 10 minutes in class,and evaluated the teaching effect by filling in the scale developed by ourselves in the end of term.Restults:Fourty students in total were involved in this study,The average score of classroom quiz was 9.87 (total score was 10),the total average score of teaching effect evaluation was 4.10,the dimension average score of curriculum design evaluation was 4.30,the dimension average score of improving ability was 4.29,the dimension average score of mastering nursing research knowledge was 3.70.Conclussions:It is feasible that using flipped classroom stragety based on learning ability in nursing ethics curriculum,and could improve the learning ability of nursing students and the teaching effect.

Objective To explore the mechanism of epinephrine in down-regulating intraocular pressure.Methods The third passage bovine trabecular meshwork cells were divided into control group and epinephrine treated groups in random fashion.Different dosages of epinephrine(10-4、10-5 and 10-6mol/L) were added in cultures and incubated for 14 days.AQP1 expressions was stained by immunocytochemistry method,and the cell area was measured by computer image analytical system.Results The expressions of AQP1 and cell areas in epinephrine treated groups was significantly lower than control group(P

AIM: To evaluate the response of obstructive sleep apnea hypopnea syndrome (OSAHS) to fluoxetine. METHODS: After a baseline polysomnography (PSG) and Epworth Sleepiness Scale (ESS) documented OSAHS, 10 patients were treated with fluoxetine (20 mg?d -1 ) for four weeks, a repeating PSG and ESS was performed to evaluate the action of fluoxetine. RESULTS: After 4 weeks fluoxetine treatment, the proportion of REM sleep time was decreased by 9.2 %, and the assessment of ESS was significantly decreased (P 0.05 ). The apnea/hypopnea index (AHI) fell in average 24.84 per hour,the mean SaO 2 and minimum SaO 2 significantly increased by 3.2 % and 16.6 %, respectively, and desaturation event index significantly decreased 18.24 per hour (P 0.05 ). The treatment efficiency of fluoxetine to OSAHS was 50%. CONCLUSION: Short term use of fluoxetine in patients with OSAHS is associated with better sleep quality, improvement in oxygenation,and reduction of episodic apneas or hypopneas.

Objective To study the expression of IL 1?,TNF ? and nitric oxide (NO) in the cervical intervertebral disc and their roles in the pathogenesis of cervical spondylotic myelopathy (CSM). Methods Fifteen cervical discs were obtained from patients of CSM undergoing anterior disc surgery. Six cervical discs specimens were obtained in the surgical operation with patients with traumatic cervical injury served as the control. The specimens were analyzed for IL 1?、TNF ? by use of ELISA method, NO was measured by optical density assays. Results The contents of IL 1?,TNF ? and NO in disc of CSM patients increased significantly when compared with the control group. Conclusion The results of the present study indicated that IL 1?,TNF ? and NO may be involved in the pathogenesis of CSM.

Three known compounds have been isolated from the marine sponge Gel-liodes spinosella in the South China Sea. The crude ethanol extract was partitioned between ethyl acetate and water, and then between w-butanol and water. The butanol fraction was chromatographed on silica gel column to obtain thymidine(1l) ,phenylacetic acid(2)and L-(-)-3-phenylanine(3). Their structures were determined by UV,IR,1HNMR,and 13CNMR data.

Two compounds were isolated from the hard coral Pavona frondifera Lamarck collected from the South China Sea by chromatographied on gel colum and recrystallization. Their structures were determined by UV,IR,MS,1HNMR and 13CNMR data. It first reported about the chemical compounds of the hard coral Pavona frondifera Lamarck.