Objective To observe the effect of oral minirin in postoperative transsphenoidal surgery patients with central diabetes insipidus. Methods The changes in the urine volume and osomlality after two weeks of minirin medication (0. lmg, 3 times each day) were observed in 34 patients with central diabetes insipidus underwent transsphenoidal surgery. Results After two weeks of minirin therapy,the average daily urine volume decreased from 7985.40 ±410. 36 ml to 2277. 87 ± 328. 94 ml,and the average plasmas osmolarity increased from 301. 68 ± 3. 59 ml/d to 313. 26 ±4. 87 mOsm/ kg. No adverse reaction was observed during the therapy. Conclusions Minirin is effective and safe in the therapy of postoperative transsphenoidal surgery patients with central diabetes insipidus.

Objective To investigate osteoporosis and its main associated factors in patients with type 2 diabetes (DM). Methods Bone mineral density(BMD)of lumbar vertebrae 2～4 and proximal femur in 40 type 2 diabetic patients were measured with dual energy X-ray absorptiometry and compared with control group(30～35 years old). Serum Ca, P, ALP and connective peptide in type 2 diabetes mellitus patients were measured. Results The area under the connective peptide releasing curre in osteoporosis group was lower than that of non-osteoporosis in type 2 diabetes. Conclu.sion BMD is correlated with the pancreatic islet function. The patients with pancreatic islet failure develop osteoporosis easily.

Objective To study the diagnosis and treatment of superior mesenteric venous thrombosis (MVT). Methods The clinical data of 13 MVT cases were retrospectively analyzed. Results The diagnosis of MVT in all 13 cases were comfirmed by surgery. Of them,diagnosis for 6 cases was made preoperatively, and misdiagnosed preoperatively in 7.11 patients were cured, and 2 died. Conclusions Because the symptom does not accord with physical sign in the early stage of MVT, the diagnosis of MVT is difficult . B US and CT are useful in the diagnosis of MTV.Intra and post operative coagulation treatment is the key to prevent the recurrence and to reduce the mortality.

[Objective]To explore the experiences of professor ZHENG Qizhong to use classical prescription treating the cold-heat complex pediatric diseases.[Method]By following professor ZHENG Qizhong, gathering the cases that are all treated by professor ZHENG Qizhong to treat pneumonia asthma case using Xiao Qinglong Decoction plus Shigao, abdominal pain and diarrhoea cases using Banxia Xiexin Decoction, diarrhoea and pertussis cases using Wumei pill, pneumonia asthma accompanied by diarrhea case using Mahuang Shengma decoction, analysing the mechanism of the upper prescription and the clinical experiences of treating cold -heat complex paediatric diseases. [Results] Cold -heat complex paediatric diseases are very common in paediatric acute or chronic diseases, professor ZHENG Qizhong has an original idea and in -depth study of classical prescription, and using them flexibly to treat various paediatric diseases such as pneumonia asthma, abdominal pain, diarrhea, pertussis, etc, and always acquires good results. [Conclusion]The clinical experiences of ZHENG Qizhong using the classical prescription to treat Cold-heat Complex Paediatric Diseases is effective and has the value to study, popularization and application.

Objective To investigate the application value of functional exercise pathway in enhanced recovery of patients undergoing hepatectomy.Methods Fifty primary hepatic carcinoma patients who had undergone liver resection in Anhui Province Hospital from December 2014 to August 2015 were randomly divided into experimental group (n =25) and control group (n =25).Postoperative length of hospital stay,hospitalization charges,complications,postoperative pain score,postoperative ambulation and intestinal ventilation time were compared between these groups.Measurement data with normal distribution were represented as ((x) ± s) and comprison between groups was analyzed using the t test.Comparisons of count data were analyzed by the x2 test.Results Postoperative length of hospital stay of the experimental group [(7.00 ± 2.27) days] were shorter than control group [(9.36 ± 4.58) days] (t =3.090,P =0.003),and hospitalization expense was lower in the experimental group [(28 184.57 ± 8 675.65) yuan] (t =2.281,P =0.025).Compared with control group (40％),the experimental group (20％) had lower overall complication incidence (t =4.286,P =4.286),and general complications incidence (8％) is lower than that in control group (24％),however,the incidence of operation characteristic complications had not statistical significance in two groups.Besides,the intestinal recovery time in the experimental group was shorter than control group (experimental group 36.56 hours,control group 45.24 hours,t =2.390,P =0.019).Conclusion The application of functional exercise pathway in postoperative enhanced recovery exercise of patients undergoing hepatectomy is safe and effective,which can reduce the patients' postoperative hospital stay,hospital costs,and the general incidence of complications incidence,and be helpful for the intestinal function recovery.

ABSTRACT:Objective To explore the application of comfort nursing in treatment of patients with percutaneous nephrolithotomy lithotripsy.Methods A total of 168 patients received percuta-neous nephrolithotomy lithotripsy were randomly divided into observation group and control group, 84 cases in each group.Both groups were treated with the same surgical approach.Patients in the control group received routine postoperative nursing and patients in the observation received comfort nursing additionally.The depression scores before and after nursing,comfort degree and satisfactory degree toward nursing and complications 3 days after nursing were observed.Results The comfort degree and satisfactory degree toward nursing in the observation group were significantly better than those in the control group(P <0.01),and the incidence rate of complications was obviously lower than the control group (P <0.05).The scores of Self-Rating Anxiety Scale (SAS)and Self-Rating Depression Scale (SDS)decreased when compared with those before nursing (P <0.01),and the scores of SAS and SDS in the observation group were significantly lower than the control group (P<0.01).Conclusion Application of comfort nursing in treatment of patients with percutaneous nephrolithotomy lithotripsy can increase the comfort degree and satisfactory degree toward nursing, reduce the depressive symptoms and the incidence of complications,so it is worthy of widely applica-tion in clinical practice.

Objective? To explore the status quo of nurses' dementia care-related literacy, caring behavior and career identity, to discuss the effects of caring behavior and career identity on dementia care-related health literacy, and to provide a basis for nursing management and professional training. Methods? In this cross-sectional study, totally 650 nurses from 10 Class Ⅲ Grade A hospitals in Beijing who had provided care in departments of geriatrics or neurology were selected by convenient sampling between April and November 2017, and investigated with the General Information Questionnaire, Caring Dimensions Inventory(CDI), Career Identity Rating Scale and Dementia Care-related Health Literacy Scale. Totally 650 questionnaires were distributed, and 602 valid questionnaires were collected, with a recovery rate of 92.6%. Results? The 602 nurses' total scores of dementia care-related health literacy, caring behavior and career identity were (74.79±7.96), (88.87±5.02) and (84.35±9.14), respectively. Correlation analysis showed that nurses' caring behavior and career were positively correlated with dementia care-related health literacy, respectively (P＜ 0.01). Hierarchical regression analysis showed that general information, caring behavior and career identity accounted for 74.5% of total variances of dementia care-related health literacy in which caring behavior could account for 33.2% and career identity 34.2%. Conclusions? Nurses' career identity and caring behavior were supplementary to their dementia care-related health literacy, which can enhance their career identity, standardize their caring behavior and improve their dementia care-related health literacy, thus providing better care services for patients with dementia.

ABSTRACT:Objective To explore the application of comfort nursing in treatment of patients with percutaneous nephrolithotomy lithotripsy.Methods A total of 168 patients received percuta-neous nephrolithotomy lithotripsy were randomly divided into observation group and control group, 84 cases in each group.Both groups were treated with the same surgical approach.Patients in the control group received routine postoperative nursing and patients in the observation received comfort nursing additionally.The depression scores before and after nursing,comfort degree and satisfactory degree toward nursing and complications 3 days after nursing were observed.Results The comfort degree and satisfactory degree toward nursing in the observation group were significantly better than those in the control group(P <0.01),and the incidence rate of complications was obviously lower than the control group (P <0.05).The scores of Self-Rating Anxiety Scale (SAS)and Self-Rating Depression Scale (SDS)decreased when compared with those before nursing (P <0.01),and the scores of SAS and SDS in the observation group were significantly lower than the control group (P<0.01).Conclusion Application of comfort nursing in treatment of patients with percutaneous nephrolithotomy lithotripsy can increase the comfort degree and satisfactory degree toward nursing, reduce the depressive symptoms and the incidence of complications,so it is worthy of widely applica-tion in clinical practice.

Objective. To investigate the exact mechanism of melatonin to prohibit the apoptosis of neural cells induced by various kinds of cytotoxic agents.Methods. We used the methods of phase contrast microscopy, MTT assay and hoechst dye staining to check this mechanism in SKNSH and U251 cell lines.Results. Both 2mmol/L H2O2 and 0.5 μ mol/L amyloid β- protein (Aβ) induce these two cell lines die via apoptosis. Either melatonin or glutathione can significantly protect both cell lines. The protective effect of 10 μ mol/L melatonin is as same as that of 60 μ mol/L glutathione.Conclusion. Melatonin can partly inhibit the cytotoxicity of H2O2 and Aβ through its role as a free radical scavenger.