Eighteen cases(20 ears) of sudden Sensorineural Hearing Loss in children had been reviewed. The results showed that the course of disease was longer before the patients receieved treatment. There may be a relationship between sudden Sensorineural Hearing Loss in children and viral infection of upper respiratory or parotitis. The effect of treatment was similar to adults. DF-521 was effective and safe for sudden Sensorineural Hearing Loss in children.