Objective To investigate the clinical value of laparoscopically assisted vaginal hysterectomy(LAVH).Methods A total of 125 cases of benign uterine diseases were freely divided into two groups: 65 cases was given LAVH(LAVH Group) and 60 cases was given traditional total abdominal hysterectomy(TAH Group).Results The operation time was 127?4.1 min in the LAVH Group and 70?1.7 min in the TAH Group(t=99.669,P=0.000).The blood loss was 80?23.1 ml in the LAVH Group and 190.8?53 ml in the TAH Group(t=-15.339,P=0.000).The incidence of postoperative complications was 30.8%(20/65) in the LAVH Group and 58.3%(35/60) in the TAH Group,with significant difference between the two groups(?~2=9.621,P=0.002).Conclusions LAVH has advantages of micro-invasion,little blood loss,and quick recovery,being an ideal procedure.

The migration of two potential contaminants, formaldehyde and acetaldehyde, from two paper materials into food simulant Tenax was studied. A rapid and simple one-step extraction-derivatization method combined with ultra high performance liquid chromatography was established for the determination of formaldehyde and acetaldehyde in paper packaging materials and food stimulants. The linear correlation coefficients (R2) were greater than 0. 9999 in the range of 0. 14-35. 7 mg/m2 for both formaldehyde and 0. 20-49. 1 mg/m2 for acetaldehyde, with detection limits of 0. 03 mg/m2 for formaldehyde and 0. 04 mg/m2 for acetaldehyde. The recoveries were 90. 1%-108. 6% for paper sample and Tenax. The migration behaviors of formaldehyde and acetaldehyde at different temperatures and migration times were investigated. Both for formaldehyde and acetaldehyde, the amount of migration gradually increased with time first, then decreased, finally reached a steady value. The migration rates of formaldehyde and acetaldehyde were differently influenced by temperature. After reaching a steady value, the maximum migration rate for formaldehyde was at 30℃, and for acetaldehyde was at 70℃ and 50℃. The migration rates of formaldehyde and acetaldehyde greatly varied, and the migration rate of acetaldehyde was far more than the migration rate of formaldehyde when reaching a steady value.

Objective:To explore the effect of a Chinese medicinal composition ( Xiadanqi) on the prevention of radon exposure induced injuries of lung in vitro and in vivo. Methods:Mice were randomly divided into three groups of blank control group, radon-exposed group alone and radon-exposed group intervened with Chinese medicinal composition. The pathological changes of lung tissues in each group after 120 WLM were observed by HE and Masson staining, and the expressions of α-SMA protein and Vimentin protein in lung tissues were detected by immunohistochemistry staining. The levels of oxidative stress in lung tissue of each group were detected with SOD and MDA kits. At the same time, a radon exposed cell model and a radon exposure + Xiadanqi intervention cell model were constructed using an ecological radon chamber. The cell adhesion abilities of different groups were detected by an adhesion kit. The cell migration ability of each group was determined by the transwell migration experiment. The expression of E-cadherin and Vimentin protein was detected by Western blot. Results:Compared with the radon exposure group, the concentration of MDA was decreased ( t=4.43, P<0.05), the activity of SOD was increased ( t=3.22, P<0.05), and α-SMA and Vimentin protein expressions were decreased ( t=3.08, 7.57, P<0.05) in lung tissue of mice intervened with 2 mg/g Xiadanqi. In vitro, compared with radon exposure group, the migration ability was reduced ( t=4.78, 13.01, P<0.05), the cell adhesion property was enhanced ( t=3.41, 12.55, P<0.05), the expression of E-cadherin protein was increased ( t=2.96, 19.57, P<0.05), and the expression of Vimentin protein was obviously reduced ( t=21.00, 33.32, P<0.05) in radon-exposed cells with the treatment of Chinese medicine (150 μg/ml and 200 μg/ml). Conclusions:The Chinese medicinal composition ( Xiadanqi) has a certain radioprotective effect on radon exposure induced injury by reducing oxidative stress, attenuating EMT and fibrosis, and thus it may be applied as a protective agent for radon induced injury.