1.Observation of detection of serum calcitonin original (PCT) in the diagnosis of pediatric infectious pneumonia
Chinese Journal of Primary Medicine and Pharmacy 2017;24(13):2052-2054
Objective To observe the serum calcitonin original (PCT) detection in the diagnosis of children with infectious pneumonia.Methods From March 2014 to April 2015,96 children with infectious pneumonia were selected,including bacterial pneumonia in 43 cases,26 cases of viral pneumonia,27 cases of Mycoplasma pneumonia.50 healthy children were selected as control group.All children received serum calcitonin original test,PCT test was applied in the diagnosis of children with infectious pneumonia.Results The PCT level in children with bacterial pneumonia group was(3.84±3.57)μg/L,which was obviously higher than (0.12±0.03)μg/L of healthy children,(0.74±0.13)μg/L of children with viral pneumonia and (1.07±0.08)μg/L of pure chlamydia pneumonia patients(F=6.120,P=0.013).Before treatment,the level of serum PCT in children with bacterial pneumonia was significantly higher than that in normal children[(3.84±3.57)μg/L vs.(0.12±0.03)μg/L,t=6.987,P=0.000].After treatment,the results of PCT detection in serum of children with bacterial pneumonia was significantly lower[(3.84±3.57)μg/L vs.(0.16±0.03)μg/L,t=6.978,P=0.000)].Conclusion Serum calcitonin original detection can effectively help the differential diagnosis of pediatric infectious pneumonia,has clinical application value.
2.Pharmaceutical Care for One Case of Subclinical Hypothyroidism Complicated with Anemia and Haemor-rhoids during Pregnancy
China Pharmacist 2017;20(9):1607-1609
Objective:To discuss the effective therapeutic regimen and the thoughts of pharmaceutical care for subclinical hypothy-roidism complicated with anemia and hemorrhoids during pregnancy. Methods:During the drug treatment process, clinical pharmacist provided pharmaceutical care for the patient,and the results were summarized and analyzed. Results: Clinical pharmacist performed pharmaceutical care for the treatment process of hypothyroidism, anemia and hemorrhoids during pregnancy, and when the oral iron treatment of hemorrhoids was with poor efficacy, clinical pharmacist analyzed and discussed the reasons and put forward reasonable sug-gestions. Conclusion:Subclinical hypothyroidism complicated with anemia and hemorrhoids during pregnancy treated with iron agent and wheat cellulose particles must pay attention to the drug interactions. The administration time of levothyroxine sodium and that of i-ron preparations and wheat cellulose particles should be staggered at least 2 hours. Because hypothyroidism can cause iron malabsorp-tion, intravenous iron therapy may be considered when oral iron supplementation shows poor effect.
3.Quality Standard of Tibet Medicine Wugen Powder
China Pharmacy 2007;0(33):-
OBJECTIVE: To establish the quality standard of Tibetan medicine Wugen powder.METHODS: The component Pleurospermum hookeri in the formulation was qualitatively identified by TLC,and the content of ferulic acid in P.hookeri was determined by HPLC.RESULTS: The TLC spots of the P.hookeri were distinctive and well-separated.The linear range of ferulic acid was 0.089 92~0.449 6 ?g(r=0.999 8) and its recovery rate was 99.42%(RSD=1.01%,n=6).CONCLUSION: The established standard is applicable for the quality control of Tibetan medicine Wugen powder.
4.Quantitative analsysis of astragaloside A and ginsenoside R_(g1) in Jiuweixinnaokang Capsules
Chinese Traditional Patent Medicine 1992;0(03):-
Objective: The active components in Radix Astragali and Radix Panacis quinguefolii of Jiuweixinnaokang Capsules: astrogaloside A and ginsenoside R g1 were determined synchronously. Methods: The dual wavelength TLC scanning was used. Results: The average recovery was 97.65% for astragaloside A (RSD=1.57%) and 97.34% for ginsenoside R g1 (RSD=2.11%).Conclusion: This method is sensitive, accurate and reproducible and can be used for the quality control of this preparation.
5.Clinical observation of sertraline in treatment of child emotional disorder
Chinese Journal of Postgraduates of Medicine 2011;34(19):16-18
Objective To explore the efficacy, safety,time of drug taking effect and therapeutic dosage of sertraline in treatment of child emotional disorder. Method One hundred and forty-seven patientswith child emotional disorder were treated by sertraline and the efficacy rate, therapeutic dosage, the time of drug taking effect and adverse reaction was analyzed retrospectively. Results One hundred and thirty-seven patients were regular visited under supervision of a physician. Two months after treatment, the efficacy rate was 80.3%(110/137) and the rate of adverse reaction was 5.8%(8/137). The therapeutic dosage of sertraline was (47.9 + 19.0) mg/d. The time of drug taking effect was (20.4±13.2) d. The therapeutic dosage of sertraline in obsessive-compulsive disorder [(58.7±26.2) mg/d] was significantly higher than that in depression[(43.6±14.0) mg/d],anxiety disorder[(44.4±10.6) mg/d] and phobia[(43.5±15.5) mg/d](P < 0.01 ). The time of drug taking effect in depression[( 14.0±6.1 ) d] was significantly shorter than that in obsessive-compulsive disorder[(26.6±16.3) d,anxiety disorder [(22.3±13.9) d] and phobia [(21.4±12.8) d] (P <0.01). Conclusions Sertraline is an efficient and safe medicine in treatment of child emotional disorder. Its adverse reaction is slight and most patients can tolerate. But it takes higher therapeutic dosage in obsessive-compulsive disorder and the time of drug taking effect is earlier in depression than in other disorder.
6.Observations on the Efficacy of Stiletto Needle Acupuncture plus Conventional Acupuncture in Treating Cervical Vertigo
Shanghai Journal of Acupuncture and Moxibustion 2015;(6):553-555
Objective To investigate the clinical efficacy of stiletto needle acupuncture plus conventional acupuncture in treating cervical vertigo. Method Sixty patients with cervical vertigo were randomly allocated to treatment and control groups. The treatment group of 30 patients received stiletto needle acupuncture plus conventional acupuncture and the control group, conventional acupuncture alone. An assessment was made using the modified Cervical Vertigo Symptom and Function Evaluation Scale in both groups before and after treatment. Result After two courses of treatment, the total efficacy rate was 93.3% in the treatment group and 73.3% in the control group; there was a statistically significant difference between the two groups (P<0.05). There was a statistically significant pre-/post-treatment difference in the symptom score in the two groups and post-treatment difference in the symptom score between the two groups (P<0.01). Conclusion Stiletto needle acupuncture plus conventional acupuncture has a definite therapeutic effect on cervical vertigo. Its therapeutic effect is superior to that of conventional acupuncture alone.
7.Epidemiology Survey Should Pay More Attention to Ethics
Chinese Medical Ethics 1995;0(03):-
The informed consent right of people who are investigated should be respected during the epidemiology survey,and there're many ethical problems about the way of inquiry,the fund of investigation,the protection of personal secrets and the compensation to people who are investigated.We should strengthen the training of investigators in order to promote the development of epidemiblogy survey.
8.Outcome of Housebound Seniors: 5 Years Follow-up
Chinese Journal of Rehabilitation Theory and Practice 2013;19(11):1087-1089
Objective To investigate the outcome of community seniors after 5 years of housebound, and the factors related with the outcome. Methods The housebound seniors confirmed 5 years ago in 5 communities in Tangshan were investigated with self-designed questionnaire and elderly depression rating scale again. Results 42.1% of the 147 housebound seniors remained housebound. There was significance between the seniors housebound and non-housebound in the factors of population sociology, such as age, spoused, economic income, housing floor, relationship with their children and social communication, and physical and psychological factors, such as health self-evaluation, loneliness and depression. Conclusion Seniors housebound in community may be reversible with some approaches of intervention.
9.Quality Standard of Erkening Misture
China Pharmacy 2005;0(24):-
OBJECTIVE: To establish the quality stangard of Erkening misture.METHODS:Raphanus sativus and Fritillaria thunbergii were identifided by TLC, and the content of the Baicalin in Erkening misture was determinated by HPLC. RESULTS: The TLC spots of Raphanus sativus and Fritillaria thunbergii were distinctive. The linear range of Baicalin was 0.319~2.64 ?g (r=0.999 3). The average recovery was 99.56%, and RSD was 0.83% (n=9). CONCLUSION: This established standard can be used for the quality control of the Erkening misture.
10.The ethical requirement of the placebo-controlled clinical study
Chinese Medical Ethics 1994;0(06):-
Placebo-controlled clinical study is the ethical issue being debated all over the time.The ethics committee plays an important role in the assurance of the scientificalness of clinical research without violation of ethics.This article introduces the main points considered in the placebo-controlled clinical study in Medical Ethics Committee of Guang'anmen Hospital of China Academy of Traditional Chinese Medicine.These points are as follows,the benefit of the subject greater than the risk,considerations on the benefit / risk of the subjects,the disposal of compensation measures and adverse events in research program and fully informed consent as well as the model of final resolution.